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The map label for this gene is ileS

Identifier: 15888029

GI number: 15888029

Start: 680863

End: 683766

Strand: Direct

Name: ileS

Synonym: Atu0686

Alternate gene names: 15888029

Gene position: 680863-683766 (Clockwise)

Preceding gene: 15888028

Following gene: 159184419

Centisome position: 23.96

GC content: 61.47

Gene sequence:

>2904_bases
ATGAGCGACACCGCAGAAAAACTGGACTATTCCACCACCCTCTATCTGCCGCAGACGGATTTTCCGATGCGTGCCGGCCT
GCCGCAGAAAGAACCGGAAACGGTGAAGCGCTGGCAGGATATGGGCCTCTACAAGAAGCTGCGCGCTTCCGCCGCCGGCC
GCGAGAAATTCGTGCTGCATGACGGCCCGCCCTATGCCAACGGCAACATCCACATCGGCCATGCGCTGAACAAAATCCTG
AAGGACGTCATCACCCGCTCGTTCCAGATGCGCGGTTTCGACGCCAATTACGTGCCCGGCTGGGATTGCCACGGCCTGCC
GATCGAATGGAAGATCGAGGAAGCCTACCGCGCCAGGGGCAAAAACAAGGACGAGGTTCCGGTCAACGAATTCCGTAAGG
AATGCCGTGACTTCGCGGCCGGCTGGATCAAGGTTCAGTCGGAAGAGTTCAAGCGTCTCGGCATCGAGGGCGACTTCGAA
AACCCCTATACGACGATGAACTTCCACGCCGAAGCCCGCATCGCCGGTGAACTCCTGAAGATCGCCCGGAGCGGCCAGCT
TTATCGCGGTTCCAAGCCCATCATGTGGTCGGTGGTCGAGCGCACGGCGCTGGCGGAAGCCGAAGTCGAATACCACGATG
TCGAGAGCGACATGATCTGGGTGAAATTCCCGGTGAAGGATGCTGCGCCCGCTCTTTCCGGCGTCTCCGTCGTCATCTGG
ACGACCACGCCGTGGACCATCCCCGGCAATCGCGCCATCGCGTTCTCTTCGCGGGTCGAATATGGCCTTTTCGAAGTCGA
AAGCGCGCAGAATGATTTTGGCCCGCAGACGGGCGAAAAGCTGATCTTCGCCAGGAAACTTGCTGACGAGGCCGCAGCCA
AGGCGAAGCTGACCTTCAAGTTCGTTCGCGATGTGAAAAGCGAAGAACTGGCGGCCATCACCTGCGCCCATCCTTTGGCA
TCACTCGGCTACGATTTCCCGGTTCCGCTTCTCGATGGCGATCACGTCACCGACGATGCCGGTACGGGTTTCGTGCACAC
CGCGCCAAGCCATGGCCGCGAGGACTTTGATGCCTGGACGAATAGCGTCCGCACCCTTGAAGCACGCGGGATCGATACCA
AAATCCCGTTCCCGGTCGATGACGCCGGTTTCTACACCGAAGACGCCCCCGGTTTCGGCCCGTCGGCCGAAGGTGGTGCG
GCCCGCGTCATGGACGACAACGGCAAGAAGGGCGATGCCAACGAGCGCGTCATCAAGGCGCTGATCGCGGCCAACAACCT
GTTTGCGCGGGGTCGTCTGAAGCACAGCTATCCGCATAGCTGGCGCTCCAAGAAGCCGGTGATCTTCCGCAACACGCCGC
AGTGGTTCGTCTACATGGACAAGGAACTCGGCGACGGCACGACGTTGCGTTCGCGTTCGCTCGATGCCATCGACCAGACC
CGCTTCGTTCCGGCTTCCGGCCAGAACCGTCTGCGCGCCATGATCGAAGGCCGGCCCGACTGGGTTCTGTCGCGCCAGCG
CAGCTGGGGCGTGCCGATCGCCGTTTTTGCCGACGAGCAGGGCGAGGTTCTGGTGGACGAAGCCGTCAACGCCCGCATCC
TCGAGGCCTTCGAGGCCGAAGGTGCGGATGCCTGGTTTGCCGAAGGTGCCAAGGAACGTTTCCTCGGCAACGACCACGAC
CATGCCAAATGGCAGCAGGTCATGGACATCCTCGATGTGTGGTTCGACAGCGGCTGCACCCATACCTTCACGCTGGAAGA
CCGCCCGGACATGAAGTGGCCGGCGGATGTCTATCTGGAAGGCTCCGACCAGCATCGCGGCTGGTTCCATTCGTCGCTGC
TGGAAAGCTGCGCGACGCGTGGCCGCGCGCCCTATAACGCCGTCGTCACCCATGGTTTCACCATGGACGAGCAGGGCCGC
AAGCAGTCCAAGTCTCTCGGCAACGTGGTTGCACCACAGGACGTGATGAAAGAGTCCGGCGCGGATATTCTGCGCCTGTG
GGTCATGACGACCGACTACTGGGAAGACCAGCGTCTGGGTAAGGCCATCATCCAGACCAACATCGATGCCTACCGCAAGC
TGCGTAACACGGTGCGCTGGATGCTCGGCACGCTCGCGCACGACAATGGCGAGGAGATCGCCTATGCCGATCTGCCGGAG
CTGGAAAAGCTGGTGCTGCACCGCCTGTCCGAGTTGGATAAGGTTGTGCGCGATGGGTACGACGCCTTCGACTTCAAGAA
GATCACCCGCGCCCTGATCGATTTCGCCAATGTCGAGCTGTCGGCGTTCTATTTCGATATCCGCAAGGACACGCTTTATT
GCGACGCGCCGTCGTCGCTGAAGCGTCGCGCATCGCTGTCGGTCATCGCCAAGCTGTTCGATTGCCTCGTCACATGGCTC
GCACCCATGCTGCCCTTCACAACTGAAGAAGCATGGCTGTCGCGCTATCCGGATGCGGAATCGGTGCATCTTGCCCAGTT
CCCGGAAATCCCGGCGGAGTGGAAGAACGACGCGTTGGAAGCCAAGTGGGAAAAAATCCGGAAGGTCCGCACCGTCGTGA
CGGGCGCGCTGGAAGTCGAGCGCCGCGAAAAGCGTATCGGCTCCTCGCTGGAGGCAGCCCCGGTCGTCCACATTGCCGAT
TCCGATCTTCTGGCGGCGCTGTCAGGACAGGACTTTGCCGAAATCTGCATCACCTCCGCCATCACGGTGGTGGGCGATGA
GGGCCCGGCCGATGGCTTCCGCTTGCAGGAAGTGGCGAAGGTCGTGGTCGAGCAGAAGCTGGCGGAAGGCGTGAAATGCG
CCCGTTCGTGGCGCATCACCACCGATGTCGGCTCCGATCCGCAATATCCCGACGTATCGGCCCGCGATGCGGCGGCACTG
CGGGAGCTTGCCGCACTCAAGTAA

Upstream 100 bases:

>100_bases
CGCTTACATGACATGTGACATATGGCATGGCGCTTTCCGAATTTGCCCTCTTTGCAATTGAGATGGCGCGACTGATACGG
CGCGCAACAACGGTACGATT

Downstream 100 bases:

>100_bases
TGAAAATGGCCGGATGAATTGCGCTTTGCCTCTTCATCCGGTACACCTGCCTGAAAATGGCCGGATTTGCACGGCAATGC
GGGCTGCCGCCTGCCGAAAG

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 967; Mature: 966

Protein sequence:

>967_residues
MSDTAEKLDYSTTLYLPQTDFPMRAGLPQKEPETVKRWQDMGLYKKLRASAAGREKFVLHDGPPYANGNIHIGHALNKIL
KDVITRSFQMRGFDANYVPGWDCHGLPIEWKIEEAYRARGKNKDEVPVNEFRKECRDFAAGWIKVQSEEFKRLGIEGDFE
NPYTTMNFHAEARIAGELLKIARSGQLYRGSKPIMWSVVERTALAEAEVEYHDVESDMIWVKFPVKDAAPALSGVSVVIW
TTTPWTIPGNRAIAFSSRVEYGLFEVESAQNDFGPQTGEKLIFARKLADEAAAKAKLTFKFVRDVKSEELAAITCAHPLA
SLGYDFPVPLLDGDHVTDDAGTGFVHTAPSHGREDFDAWTNSVRTLEARGIDTKIPFPVDDAGFYTEDAPGFGPSAEGGA
ARVMDDNGKKGDANERVIKALIAANNLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKELGDGTTLRSRSLDAIDQT
RFVPASGQNRLRAMIEGRPDWVLSRQRSWGVPIAVFADEQGEVLVDEAVNARILEAFEAEGADAWFAEGAKERFLGNDHD
HAKWQQVMDILDVWFDSGCTHTFTLEDRPDMKWPADVYLEGSDQHRGWFHSSLLESCATRGRAPYNAVVTHGFTMDEQGR
KQSKSLGNVVAPQDVMKESGADILRLWVMTTDYWEDQRLGKAIIQTNIDAYRKLRNTVRWMLGTLAHDNGEEIAYADLPE
LEKLVLHRLSELDKVVRDGYDAFDFKKITRALIDFANVELSAFYFDIRKDTLYCDAPSSLKRRASLSVIAKLFDCLVTWL
APMLPFTTEEAWLSRYPDAESVHLAQFPEIPAEWKNDALEAKWEKIRKVRTVVTGALEVERREKRIGSSLEAAPVVHIAD
SDLLAALSGQDFAEICITSAITVVGDEGPADGFRLQEVAKVVVEQKLAEGVKCARSWRITTDVGSDPQYPDVSARDAAAL
RELAALK

Sequences:

>Translated_967_residues
MSDTAEKLDYSTTLYLPQTDFPMRAGLPQKEPETVKRWQDMGLYKKLRASAAGREKFVLHDGPPYANGNIHIGHALNKIL
KDVITRSFQMRGFDANYVPGWDCHGLPIEWKIEEAYRARGKNKDEVPVNEFRKECRDFAAGWIKVQSEEFKRLGIEGDFE
NPYTTMNFHAEARIAGELLKIARSGQLYRGSKPIMWSVVERTALAEAEVEYHDVESDMIWVKFPVKDAAPALSGVSVVIW
TTTPWTIPGNRAIAFSSRVEYGLFEVESAQNDFGPQTGEKLIFARKLADEAAAKAKLTFKFVRDVKSEELAAITCAHPLA
SLGYDFPVPLLDGDHVTDDAGTGFVHTAPSHGREDFDAWTNSVRTLEARGIDTKIPFPVDDAGFYTEDAPGFGPSAEGGA
ARVMDDNGKKGDANERVIKALIAANNLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKELGDGTTLRSRSLDAIDQT
RFVPASGQNRLRAMIEGRPDWVLSRQRSWGVPIAVFADEQGEVLVDEAVNARILEAFEAEGADAWFAEGAKERFLGNDHD
HAKWQQVMDILDVWFDSGCTHTFTLEDRPDMKWPADVYLEGSDQHRGWFHSSLLESCATRGRAPYNAVVTHGFTMDEQGR
KQSKSLGNVVAPQDVMKESGADILRLWVMTTDYWEDQRLGKAIIQTNIDAYRKLRNTVRWMLGTLAHDNGEEIAYADLPE
LEKLVLHRLSELDKVVRDGYDAFDFKKITRALIDFANVELSAFYFDIRKDTLYCDAPSSLKRRASLSVIAKLFDCLVTWL
APMLPFTTEEAWLSRYPDAESVHLAQFPEIPAEWKNDALEAKWEKIRKVRTVVTGALEVERREKRIGSSLEAAPVVHIAD
SDLLAALSGQDFAEICITSAITVVGDEGPADGFRLQEVAKVVVEQKLAEGVKCARSWRITTDVGSDPQYPDVSARDAAAL
RELAALK
>Mature_966_residues
SDTAEKLDYSTTLYLPQTDFPMRAGLPQKEPETVKRWQDMGLYKKLRASAAGREKFVLHDGPPYANGNIHIGHALNKILK
DVITRSFQMRGFDANYVPGWDCHGLPIEWKIEEAYRARGKNKDEVPVNEFRKECRDFAAGWIKVQSEEFKRLGIEGDFEN
PYTTMNFHAEARIAGELLKIARSGQLYRGSKPIMWSVVERTALAEAEVEYHDVESDMIWVKFPVKDAAPALSGVSVVIWT
TTPWTIPGNRAIAFSSRVEYGLFEVESAQNDFGPQTGEKLIFARKLADEAAAKAKLTFKFVRDVKSEELAAITCAHPLAS
LGYDFPVPLLDGDHVTDDAGTGFVHTAPSHGREDFDAWTNSVRTLEARGIDTKIPFPVDDAGFYTEDAPGFGPSAEGGAA
RVMDDNGKKGDANERVIKALIAANNLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKELGDGTTLRSRSLDAIDQTR
FVPASGQNRLRAMIEGRPDWVLSRQRSWGVPIAVFADEQGEVLVDEAVNARILEAFEAEGADAWFAEGAKERFLGNDHDH
AKWQQVMDILDVWFDSGCTHTFTLEDRPDMKWPADVYLEGSDQHRGWFHSSLLESCATRGRAPYNAVVTHGFTMDEQGRK
QSKSLGNVVAPQDVMKESGADILRLWVMTTDYWEDQRLGKAIIQTNIDAYRKLRNTVRWMLGTLAHDNGEEIAYADLPEL
EKLVLHRLSELDKVVRDGYDAFDFKKITRALIDFANVELSAFYFDIRKDTLYCDAPSSLKRRASLSVIAKLFDCLVTWLA
PMLPFTTEEAWLSRYPDAESVHLAQFPEIPAEWKNDALEAKWEKIRKVRTVVTGALEVERREKRIGSSLEAAPVVHIADS
DLLAALSGQDFAEICITSAITVVGDEGPADGFRLQEVAKVVVEQKLAEGVKCARSWRITTDVGSDPQYPDVSARDAAALR
ELAALK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI46852147, Length=991, Percent_Identity=34.9142280524723, Blast_Score=534, Evalue=1e-151,
Organism=Homo sapiens, GI94721239, Length=903, Percent_Identity=24.4739756367663, Blast_Score=259, Evalue=7e-69,
Organism=Homo sapiens, GI94721241, Length=903, Percent_Identity=24.4739756367663, Blast_Score=259, Evalue=7e-69,
Organism=Homo sapiens, GI5454158, Length=874, Percent_Identity=22.6544622425629, Blast_Score=154, Evalue=5e-37,
Organism=Homo sapiens, GI268370293, Length=901, Percent_Identity=22.6415094339623, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI268370297, Length=901, Percent_Identity=22.6415094339623, Blast_Score=143, Evalue=8e-34,
Organism=Homo sapiens, GI268370295, Length=873, Percent_Identity=22.680412371134, Blast_Score=140, Evalue=6e-33,
Organism=Escherichia coli, GI2367096, Length=974, Percent_Identity=40.7597535934292, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1790708, Length=902, Percent_Identity=20.8425720620843, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71980946, Length=849, Percent_Identity=31.8021201413428, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17541896, Length=868, Percent_Identity=26.036866359447, Blast_Score=273, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17510661, Length=897, Percent_Identity=22.742474916388, Blast_Score=175, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI72001587, Length=609, Percent_Identity=25.615763546798, Blast_Score=135, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6325217, Length=865, Percent_Identity=33.5260115606936, Blast_Score=440, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6319395, Length=925, Percent_Identity=25.4054054054054, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6321531, Length=859, Percent_Identity=23.7485448195576, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281366294, Length=883, Percent_Identity=34.3148357870895, Blast_Score=457, Evalue=1e-128,
Organism=Drosophila melanogaster, GI28574730, Length=931, Percent_Identity=26.530612244898, Blast_Score=283, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24668547, Length=931, Percent_Identity=26.530612244898, Blast_Score=283, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24668543, Length=931, Percent_Identity=26.530612244898, Blast_Score=283, Evalue=5e-76,
Organism=Drosophila melanogaster, GI17864482, Length=867, Percent_Identity=23.1833910034602, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24653289, Length=867, Percent_Identity=23.1833910034602, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21355675, Length=910, Percent_Identity=21.7582417582418, Blast_Score=142, Evalue=1e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_AGRT5 (Q8UHJ6)

Other databases:

- EMBL:   AE007869
- PIR:   AH2660
- PIR:   F97442
- RefSeq:   NP_353710.1
- ProteinModelPortal:   Q8UHJ6
- STRING:   Q8UHJ6
- GeneID:   1138191
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0686
- eggNOG:   COG0060
- HOGENOM:   HBG577712
- OMA:   KQVLTHG
- PhylomeDB:   Q8UHJ6
- ProtClustDB:   PRK13804
- BioCyc:   ATUM176299-1:ATU0686-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02002
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 108483; Mature: 108352

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 600-600 BINDING 644-644

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAEKLDYSTTLYLPQTDFPMRAGLPQKEPETVKRWQDMGLYKKLRASAAGREKFVLH
CCCHHHHCCCCEEEEECCCCCCHHCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEE
DGPPYANGNIHIGHALNKILKDVITRSFQMRGFDANYVPGWDCHGLPIEWKIEEAYRARG
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCC
KNKDEVPVNEFRKECRDFAAGWIKVQSEEFKRLGIEGDFENPYTTMNFHAEARIAGELLK
CCCCCCCHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHH
IARSGQLYRGSKPIMWSVVERTALAEAEVEYHDVESDMIWVKFPVKDAAPALSGVSVVIW
HHHCCCEEECCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHCCCCCCCEEEEE
TTTPWTIPGNRAIAFSSRVEYGLFEVESAQNDFGPQTGEKLIFARKLADEAAAKAKLTFK
ECCCEECCCCCEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FVRDVKSEELAAITCAHPLASLGYDFPVPLLDGDHVTDDAGTGFVHTAPSHGREDFDAWT
HHHHCCCCHHEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHH
NSVRTLEARGIDTKIPFPVDDAGFYTEDAPGFGPSAEGGAARVMDDNGKKGDANERVIKA
HHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHH
LIAANNLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKELGDGTTLRSRSLDAIDQT
HHHHCCHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCEECCCCCCHHHHC
RFVPASGQNRLRAMIEGRPDWVLSRQRSWGVPIAVFADEQGEVLVDEAVNARILEAFEAE
EECCCCCCHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCEEEHHHHCHHHHHHHHCC
GADAWFAEGAKERFLGNDHDHAKWQQVMDILDVWFDSGCTHTFTLEDRPDMKWPADVYLE
CCCHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEE
GSDQHRGWFHSSLLESCATRGRAPYNAVVTHGFTMDEQGRKQSKSLGNVVAPQDVMKESG
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCC
ADILRLWVMTTDYWEDQRLGKAIIQTNIDAYRKLRNTVRWMLGTLAHDNGEEIAYADLPE
CCEEEEEEHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
LEKLVLHRLSELDKVVRDGYDAFDFKKITRALIDFANVELSAFYFDIRKDTLYCDAPSSL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEECCEEEECCCHHH
KRRASLSVIAKLFDCLVTWLAPMLPFTTEEAWLSRYPDAESVHLAQFPEIPAEWKNDALE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEHHHCCCCCCHHCCCHHH
AKWEKIRKVRTVVTGALEVERREKRIGSSLEAAPVVHIADSDLLAALSGQDFAEICITSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHH
ITVVGDEGPADGFRLQEVAKVVVEQKLAEGVKCARSWRITTDVGSDPQYPDVSARDAAAL
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHH
RELAALK
HHHHHCC
>Mature Secondary Structure 
SDTAEKLDYSTTLYLPQTDFPMRAGLPQKEPETVKRWQDMGLYKKLRASAAGREKFVLH
CCHHHHCCCCEEEEECCCCCCHHCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCEEEEE
DGPPYANGNIHIGHALNKILKDVITRSFQMRGFDANYVPGWDCHGLPIEWKIEEAYRARG
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCC
KNKDEVPVNEFRKECRDFAAGWIKVQSEEFKRLGIEGDFENPYTTMNFHAEARIAGELLK
CCCCCCCHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHH
IARSGQLYRGSKPIMWSVVERTALAEAEVEYHDVESDMIWVKFPVKDAAPALSGVSVVIW
HHHCCCEEECCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCHHCCCCCCCEEEEE
TTTPWTIPGNRAIAFSSRVEYGLFEVESAQNDFGPQTGEKLIFARKLADEAAAKAKLTFK
ECCCEECCCCCEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FVRDVKSEELAAITCAHPLASLGYDFPVPLLDGDHVTDDAGTGFVHTAPSHGREDFDAWT
HHHHCCCCHHEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHH
NSVRTLEARGIDTKIPFPVDDAGFYTEDAPGFGPSAEGGAARVMDDNGKKGDANERVIKA
HHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHH
LIAANNLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKELGDGTTLRSRSLDAIDQT
HHHHCCHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCEECCCCCCHHHHC
RFVPASGQNRLRAMIEGRPDWVLSRQRSWGVPIAVFADEQGEVLVDEAVNARILEAFEAE
EECCCCCCHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCEEEHHHHCHHHHHHHHCC
GADAWFAEGAKERFLGNDHDHAKWQQVMDILDVWFDSGCTHTFTLEDRPDMKWPADVYLE
CCCHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEE
GSDQHRGWFHSSLLESCATRGRAPYNAVVTHGFTMDEQGRKQSKSLGNVVAPQDVMKESG
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCC
ADILRLWVMTTDYWEDQRLGKAIIQTNIDAYRKLRNTVRWMLGTLAHDNGEEIAYADLPE
CCEEEEEEHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
LEKLVLHRLSELDKVVRDGYDAFDFKKITRALIDFANVELSAFYFDIRKDTLYCDAPSSL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEECCEEEECCCHHH
KRRASLSVIAKLFDCLVTWLAPMLPFTTEEAWLSRYPDAESVHLAQFPEIPAEWKNDALE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEHHHCCCCCCHHCCCHHH
AKWEKIRKVRTVVTGALEVERREKRIGSSLEAAPVVHIADSDLLAALSGQDFAEICITSA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHH
ITVVGDEGPADGFRLQEVAKVVVEQKLAEGVKCARSWRITTDVGSDPQYPDVSARDAAAL
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHH
RELAALK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194