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The map label for this gene is dgdR [H]

Identifier: 15887996

GI number: 15887996

Start: 648223

End: 649173

Strand: Reverse

Name: dgdR [H]

Synonym: Atu0654

Alternate gene names: 15887996

Gene position: 649173-648223 (Counterclockwise)

Preceding gene: 15887998

Following gene: 15887994

Centisome position: 22.85

GC content: 62.25

Gene sequence:

>951_bases
ATGTCCGCACCTCTCGACATCGACCAGCTGCATACCTTCATCGCCATCATCGATACGGGCAGCTTTACCAAAGCCGCTGA
CCGCGTTTTCAAGACGCAATCCGCCGTCTCCATGCAGATGCGGCGACTTGAAGAACGCATCGGCAAACAGCTCTTTGCAA
AAGACGGCCGAGGCAATCGCCTGACCGCGGAGGGCGAAAAGCTGATGAATTATGCCCGCCGCATCATCCGCCTCAACAAT
GAGGCGATCGCCGCCTTCGATGACAACCGGCTGGAAGGCACGCTGCGCATCGGCACCCCTGATGACTATGCCGACCGCTA
CATGCCTGAAATCATCGGGCGTTTCGCCAAGACCCATCCGAATGTCGAGCTTTATATCGTCTGCGAACCTTCGGTCAGCC
TTGCCGAAAAAATGGCGCGCGGCGAACTGGATATCGCGCTCGTTACCCATAATCCCCGTGCACGCTCCTCCGATGTGGTG
CGAACCGAGCCGCTCTGCTGGGTCGCCTCCGCCAACCATCCGCTGAAGGACGACGCGCCGGTGCCGCTCGCCGTCGGGCG
GCGCGATTGCCACTGGCGCCAGCTTGCCTGTTCGGCGCTCGATGCCGACGGGCGGGATTATCAGGTTCTGTTCACAAGCT
GGTCTTCCACCGTGGTCGCCGCCGCGGTGCTGGCGGGCATGGCCGTTTCGGTGCTGCCGGAATCGGCGCTGCGCACCGGC
ATGAAGGTGCTGACCGCCGCCGATGGTTTCCCACCGCTGCCGCCGGTGCAGATCGGCCTGATGAAGCGCCCCGGTCTCTC
GCCTTCGCTGGTGAACGCCATTACCGACCACATCACCGCCTGCCTCGATAATATCTCGCCGATGAGCGTTGTCGACGAGA
TGGACAGTGATGTGAAGACCTACCCCAAGATGCCGCGCCTGCGCGCCGGGCATATGCTGCCGGGATGGTGA

Upstream 100 bases:

>100_bases
TGATACTGATTTGCTTGGTGTCAAAATGTCGCAAGACTATTGATCAGTCCAACGAATGTTTCTAATGTGAGACATCAATC
ATTCTGATGGATGACACTCC

Downstream 100 bases:

>100_bases
GATGCCTAAGGCCGGATAGCCCGGCCTTTCTGTTGTCGGCTTATCGTGCCCGCAACGTTGCGACCGCCAGCAGCGTGTCG
CCGCTGATACCCGCCGAGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSAPLDIDQLHTFIAIIDTGSFTKAADRVFKTQSAVSMQMRRLEERIGKQLFAKDGRGNRLTAEGEKLMNYARRIIRLNN
EAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHPNVELYIVCEPSVSLAEKMARGELDIALVTHNPRARSSDVV
RTEPLCWVASANHPLKDDAPVPLAVGRRDCHWRQLACSALDADGRDYQVLFTSWSSTVVAAAVLAGMAVSVLPESALRTG
MKVLTAADGFPPLPPVQIGLMKRPGLSPSLVNAITDHITACLDNISPMSVVDEMDSDVKTYPKMPRLRAGHMLPGW

Sequences:

>Translated_316_residues
MSAPLDIDQLHTFIAIIDTGSFTKAADRVFKTQSAVSMQMRRLEERIGKQLFAKDGRGNRLTAEGEKLMNYARRIIRLNN
EAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHPNVELYIVCEPSVSLAEKMARGELDIALVTHNPRARSSDVV
RTEPLCWVASANHPLKDDAPVPLAVGRRDCHWRQLACSALDADGRDYQVLFTSWSSTVVAAAVLAGMAVSVLPESALRTG
MKVLTAADGFPPLPPVQIGLMKRPGLSPSLVNAITDHITACLDNISPMSVVDEMDSDVKTYPKMPRLRAGHMLPGW
>Mature_315_residues
SAPLDIDQLHTFIAIIDTGSFTKAADRVFKTQSAVSMQMRRLEERIGKQLFAKDGRGNRLTAEGEKLMNYARRIIRLNNE
AIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHPNVELYIVCEPSVSLAEKMARGELDIALVTHNPRARSSDVVR
TEPLCWVASANHPLKDDAPVPLAVGRRDCHWRQLACSALDADGRDYQVLFTSWSSTVVAAAVLAGMAVSVLPESALRTGM
KVLTAADGFPPLPPVQIGLMKRPGLSPSLVNAITDHITACLDNISPMSVVDEMDSDVKTYPKMPRLRAGHMLPGW

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=294, Percent_Identity=33.6734693877551, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI157672245, Length=181, Percent_Identity=29.2817679558011, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=26.8817204301075, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=155, Percent_Identity=30.9677419354839, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=28.1632653061224, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=180, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=30.3448275862069, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081904, Length=186, Percent_Identity=26.3440860215054, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI48994962, Length=179, Percent_Identity=27.9329608938547, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082132, Length=243, Percent_Identity=24.6913580246914, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=187, Percent_Identity=28.8770053475936, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=299, Percent_Identity=24.0802675585284, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=145, Percent_Identity=26.8965517241379, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=305, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=22.4, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787589, Length=126, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786713, Length=69, Percent_Identity=46.3768115942029, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788296, Length=232, Percent_Identity=26.2931034482759, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=146, Percent_Identity=29.4520547945205, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34764; Mature: 34633

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPLDIDQLHTFIAIIDTGSFTKAADRVFKTQSAVSMQMRRLEERIGKQLFAKDGRGNR
CCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LTAEGEKLMNYARRIIRLNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHP
ECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
NVELYIVCEPSVSLAEKMARGELDIALVTHNPRARSSDVVRTEPLCWVASANHPLKDDAP
CEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCEEEEECCCCCCCCCCC
VPLAVGRRDCHWRQLACSALDADGRDYQVLFTSWSSTVVAAAVLAGMAVSVLPESALRTG
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHH
MKVLTAADGFPPLPPVQIGLMKRPGLSPSLVNAITDHITACLDNISPMSVVDEMDSDVKT
HHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHH
YPKMPRLRAGHMLPGW
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPLDIDQLHTFIAIIDTGSFTKAADRVFKTQSAVSMQMRRLEERIGKQLFAKDGRGNR
CCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LTAEGEKLMNYARRIIRLNNEAIAAFDDNRLEGTLRIGTPDDYADRYMPEIIGRFAKTHP
ECCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
NVELYIVCEPSVSLAEKMARGELDIALVTHNPRARSSDVVRTEPLCWVASANHPLKDDAP
CEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCEEEEECCCCCCCCCCC
VPLAVGRRDCHWRQLACSALDADGRDYQVLFTSWSSTVVAAAVLAGMAVSVLPESALRTG
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHH
MKVLTAADGFPPLPPVQIGLMKRPGLSPSLVNAITDHITACLDNISPMSVVDEMDSDVKT
HHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHH
YPKMPRLRAGHMLPGW
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]