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The map label for this gene is ubiA [H]

Identifier: 15887993

GI number: 15887993

Start: 643780

End: 644733

Strand: Direct

Name: ubiA [H]

Synonym: Atu0651

Alternate gene names: 15887993

Gene position: 643780-644733 (Clockwise)

Preceding gene: 159184407

Following gene: 15887995

Centisome position: 22.66

GC content: 59.96

Gene sequence:

>954_bases
ATGGTTCACCACAGCGATTTGTCAGACCGCGTTTCCGACGCGCCATCCAACAACTGGGTCTATCGGATTTTGCCGAGGCC
CCTCTGGCCTTATGCGCAGCTGGCACGGTGGGATCGTCCCATTGGCTGGCAATTACTGATGTGGCCGTGTTTCTGGGCCG
CAGCCCTCGCGGCCAATGCGGCAGTGGCGACTGGCGGCTTTTCCTGGGGCACGTTGATCTGGCATCTCGTGCTGTTCTTC
ATCGGATCGGTGGCGATGCGCGGCGCGGGCTGCACCTATAATGATCTCGCCGACCACAAGATCGACATGGCCGTGGCGCG
CACCCGCTCGCGGCCGCTGCCATCGGGCCGGGTGAGCCGCGGGCAGGCCAAGCTCTTCATCGTGCTGCAGGCGCTTGCCG
GGCTGGTTGTGCTTTTGCAGTTCAACGGTTTCGCTGTTATCACCGGCATAGCCTCGCTGGTCTTCGTGGCGATCTATCCC
TTCGCCAAGCGCTTTACCAACTGGCCGCAATTTTTCCTCGGGCTCGCATTTTCCTGGGGTGCGCTGATGGGCTGGGCCGG
GCAGTTCGGTTCTCTCGCCTGGCCGGCTGTCCTGCTTTATGTCGGTTCCATCGCCTGGACGATCGGTTATGATACAATCT
ACGCCCATCAGGACAAGGAAGACGACACGGCCGTGGGCATCGGCTCGACCGCGCTGCTGTTTGGAGAAAACACACATCGC
TGGCTGGTTGTCCTTTATGGCACAGCCCTTGTCATGATTTTCCTGTCGTTCTGGACGGCGGGTGTTAACATTATTGCCTA
TAGTGGCCTTGCCGCTGCCGCCATCATGCTGTTCCGGCAGGTCTGGGTGCTCGATATCGACAACGTCGACCAATGCCTCG
TGCTGTTCAAATCCAACAACCGTGTCGGCGTGCTGATTTTTGCCGGTCTCATCCTGCCGCTGCTGCTGGCGTAA

Upstream 100 bases:

>100_bases
ATGTGAAGCCCCGTTGCGAAGCCGCTGCGGGGCTTTTTTGCATGCGGGCGGGGTGCTGAAATCCATTCCGATTTTTTTGC
CAATGCTGTAGAACCATCGC

Downstream 100 bases:

>100_bases
GTTGCGGGAATAGGGAATACGAAAAAGCCCGGTCGCGTCATCCGCACCGGGCTTTTATGTTCTGGACTGAAGAAGATCAG
CTGCGGGCGATGATTTCCTT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MVHHSDLSDRVSDAPSNNWVYRILPRPLWPYAQLARWDRPIGWQLLMWPCFWAAALAANAAVATGGFSWGTLIWHLVLFF
IGSVAMRGAGCTYNDLADHKIDMAVARTRSRPLPSGRVSRGQAKLFIVLQALAGLVVLLQFNGFAVITGIASLVFVAIYP
FAKRFTNWPQFFLGLAFSWGALMGWAGQFGSLAWPAVLLYVGSIAWTIGYDTIYAHQDKEDDTAVGIGSTALLFGENTHR
WLVVLYGTALVMIFLSFWTAGVNIIAYSGLAAAAIMLFRQVWVLDIDNVDQCLVLFKSNNRVGVLIFAGLILPLLLA

Sequences:

>Translated_317_residues
MVHHSDLSDRVSDAPSNNWVYRILPRPLWPYAQLARWDRPIGWQLLMWPCFWAAALAANAAVATGGFSWGTLIWHLVLFF
IGSVAMRGAGCTYNDLADHKIDMAVARTRSRPLPSGRVSRGQAKLFIVLQALAGLVVLLQFNGFAVITGIASLVFVAIYP
FAKRFTNWPQFFLGLAFSWGALMGWAGQFGSLAWPAVLLYVGSIAWTIGYDTIYAHQDKEDDTAVGIGSTALLFGENTHR
WLVVLYGTALVMIFLSFWTAGVNIIAYSGLAAAAIMLFRQVWVLDIDNVDQCLVLFKSNNRVGVLIFAGLILPLLLA
>Mature_317_residues
MVHHSDLSDRVSDAPSNNWVYRILPRPLWPYAQLARWDRPIGWQLLMWPCFWAAALAANAAVATGGFSWGTLIWHLVLFF
IGSVAMRGAGCTYNDLADHKIDMAVARTRSRPLPSGRVSRGQAKLFIVLQALAGLVVLLQFNGFAVITGIASLVFVAIYP
FAKRFTNWPQFFLGLAFSWGALMGWAGQFGSLAWPAVLLYVGSIAWTIGYDTIYAHQDKEDDTAVGIGSTALLFGENTHR
WLVVLYGTALVMIFLSFWTAGVNIIAYSGLAAAAIMLFRQVWVLDIDNVDQCLVLFKSNNRVGVLIFAGLILPLLLA

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=290, Percent_Identity=42.4137931034483, Blast_Score=211, Evalue=5e-55,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=36.2989323843416, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17553718, Length=294, Percent_Identity=42.5170068027211, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI32565247, Length=295, Percent_Identity=40.6779661016949, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17553720, Length=351, Percent_Identity=35.042735042735, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32565245, Length=150, Percent_Identity=44, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=149, Percent_Identity=43.6241610738255, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=284, Percent_Identity=38.0281690140845, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21355567, Length=288, Percent_Identity=46.5277777777778, Blast_Score=242, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34957; Mature: 34957

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHHSDLSDRVSDAPSNNWVYRILPRPLWPYAQLARWDRPIGWQLLMWPCFWAAALAANA
CCCCCCCHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
AVATGGFSWGTLIWHLVLFFIGSVAMRGAGCTYNDLADHKIDMAVARTRSRPLPSGRVSR
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GQAKLFIVLQALAGLVVLLQFNGFAVITGIASLVFVAIYPFAKRFTNWPQFFLGLAFSWG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ALMGWAGQFGSLAWPAVLLYVGSIAWTIGYDTIYAHQDKEDDTAVGIGSTALLFGENTHR
HHHHHHHCCCCHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCEECCCCEEEEECCCCCE
WLVVLYGTALVMIFLSFWTAGVNIIAYSGLAAAAIMLFRQVWVLDIDNVDQCLVLFKSNN
EEEHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHHHHHHEECCCCCEEEEEEECCC
RVGVLIFAGLILPLLLA
CEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MVHHSDLSDRVSDAPSNNWVYRILPRPLWPYAQLARWDRPIGWQLLMWPCFWAAALAANA
CCCCCCCHHHHHCCCCCCCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
AVATGGFSWGTLIWHLVLFFIGSVAMRGAGCTYNDLADHKIDMAVARTRSRPLPSGRVSR
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GQAKLFIVLQALAGLVVLLQFNGFAVITGIASLVFVAIYPFAKRFTNWPQFFLGLAFSWG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ALMGWAGQFGSLAWPAVLLYVGSIAWTIGYDTIYAHQDKEDDTAVGIGSTALLFGENTHR
HHHHHHHCCCCHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCEECCCCEEEEECCCCCE
WLVVLYGTALVMIFLSFWTAGVNIIAYSGLAAAAIMLFRQVWVLDIDNVDQCLVLFKSNN
EEEHHHHHHHHHHHHHHHHCCCHHEEECHHHHHHHHHHHHHHHEECCCCCEEEEEEECCC
RVGVLIFAGLILPLLLA
CEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA