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The map label for this gene is aroA [H]

Identifier: 15887983

GI number: 15887983

Start: 628400

End: 629677

Strand: Direct

Name: aroA [H]

Synonym: Atu0642

Alternate gene names: 15887983

Gene position: 628400-629677 (Clockwise)

Preceding gene: 15887982

Following gene: 159184402

Centisome position: 22.11

GC content: 63.07

Gene sequence:

>1278_bases
ATGATCGAACTGACCATCACCCCGCCCGGCCACCCGCTTTCCGGCAAGGTGGAGCCGCCCGGCTCCAAATCCATCACCAA
CCGCGCGCTTCTCTTGGCCGGCCTCGCCAAGGGCAAAAGCCACTTGTCAGGCGCCCTGAAAAGCGACGATACGCTTTATA
TGGCCGAAGCTCTGCGGGAGATGGGCGTGAAGGTCACCGAGCCTGACGCCACCACCTTCGTGGTGGAGGGAACGGGCGTG
CTGCAGCAGCCGGAAAAGCCGCTGTTCCTCGGCAATGCCGGCACCGCCACGCGGTTCCTGACTGCCGCCGGGGCACTTGT
CGATGGCGCCGTCATCATCGATGGGGACGAACATATGCGCAAACGCCCGATACTGCCGCTGGTGCAGGCGCTGCGGGCTC
TCGGCGTGGAAGCGGATGCGCCAACCGGCTGCCCGCCTGTCACCGTCCGTGGCAAGGGTATGGGTTTTCCAAAGGGCAGC
GTCACCATCGACGCCAATCTCTCCAGCCAGTATGTGTCGGCACTGTTGATGGCCGCCGCCTGCGGTGACAAGCCCGTGGA
TATCATCCTGAAGGGTGAGGAAATCGGCGCGAAGGGCTATATCGACCTCACCACATCCGCCATGGAAGCCTTCGGAGCGA
AGGTGGAGCGGGTCAGCAACGCCATCTGGCGCGTGCATCCGACCGGTTACACGGCAACCGATTTCCACATCGAGCCGGAT
GCCTCCGCCGCCACCTATCTCTGGGGCGCGGAGCTTCTGACCGGCGGTGCTATCGATATCGGCACGCCCGCTGACAAATT
CACTCAGCCGGATGCCAAGGCTTATGAGGTCATGGCGCAGTTTCCGCATCTGCCCGCCGAAATCGACGGTTCGCAGATGC
AGGACGCCATTCCAACCATCGCGGTTATCGCCGCCTTCAACGAGACGCCGGTGCGTTTCGTCGGCATCGCCAATCTGCGC
GTCAAGGAATGCGACCGCATCCGCGCCGTCTCGCTCGGCCTCAACGAAATCCGCGAGGGTCTGGCGCATGAAGAGGGTGA
CGACCTGATCGTACATGCCGATCCGTCGCTCGCCGGGCAGACGGTCGATGCCTCCATCGATACCTTTGCCGATCACCGCA
TCGCCATGAGTTTTGCACTGGCGGCGCTCAAGATCGGAGGCATCGCCATCCAGAATCCCGCCTGCGTGGCCAAGACCTAT
CCGGGCTACTGGAAAGCGCTTGCCTCGCTCGGCGTCGACTATACCGAAAAGGAAAGCGCTGCCGAGCCGCAGCACTGA

Upstream 100 bases:

>100_bases
GCGCCGTGCCGACCGTGAAATTCTAAGCACCGGCTCCCAATCTCCCGCCGATATTCCGATAGCCCGGCTCCGTGCCGCAT
TCTTTGACAAGACGACGATC

Downstream 100 bases:

>100_bases
AGCCATTAGGGAGGGATCACCCGTGAAGACCATCGCCGCAAGACTTCTCGCGCTGTTCGTCTTCCTGGGCGTCGCCTTCC
CGGCCTTTGCCGAGGAATTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MIELTITPPGHPLSGKVEPPGSKSITNRALLLAGLAKGKSHLSGALKSDDTLYMAEALREMGVKVTEPDATTFVVEGTGV
LQQPEKPLFLGNAGTATRFLTAAGALVDGAVIIDGDEHMRKRPILPLVQALRALGVEADAPTGCPPVTVRGKGMGFPKGS
VTIDANLSSQYVSALLMAAACGDKPVDIILKGEEIGAKGYIDLTTSAMEAFGAKVERVSNAIWRVHPTGYTATDFHIEPD
ASAATYLWGAELLTGGAIDIGTPADKFTQPDAKAYEVMAQFPHLPAEIDGSQMQDAIPTIAVIAAFNETPVRFVGIANLR
VKECDRIRAVSLGLNEIREGLAHEEGDDLIVHADPSLAGQTVDASIDTFADHRIAMSFALAALKIGGIAIQNPACVAKTY
PGYWKALASLGVDYTEKESAAEPQH

Sequences:

>Translated_425_residues
MIELTITPPGHPLSGKVEPPGSKSITNRALLLAGLAKGKSHLSGALKSDDTLYMAEALREMGVKVTEPDATTFVVEGTGV
LQQPEKPLFLGNAGTATRFLTAAGALVDGAVIIDGDEHMRKRPILPLVQALRALGVEADAPTGCPPVTVRGKGMGFPKGS
VTIDANLSSQYVSALLMAAACGDKPVDIILKGEEIGAKGYIDLTTSAMEAFGAKVERVSNAIWRVHPTGYTATDFHIEPD
ASAATYLWGAELLTGGAIDIGTPADKFTQPDAKAYEVMAQFPHLPAEIDGSQMQDAIPTIAVIAAFNETPVRFVGIANLR
VKECDRIRAVSLGLNEIREGLAHEEGDDLIVHADPSLAGQTVDASIDTFADHRIAMSFALAALKIGGIAIQNPACVAKTY
PGYWKALASLGVDYTEKESAAEPQH
>Mature_425_residues
MIELTITPPGHPLSGKVEPPGSKSITNRALLLAGLAKGKSHLSGALKSDDTLYMAEALREMGVKVTEPDATTFVVEGTGV
LQQPEKPLFLGNAGTATRFLTAAGALVDGAVIIDGDEHMRKRPILPLVQALRALGVEADAPTGCPPVTVRGKGMGFPKGS
VTIDANLSSQYVSALLMAAACGDKPVDIILKGEEIGAKGYIDLTTSAMEAFGAKVERVSNAIWRVHPTGYTATDFHIEPD
ASAATYLWGAELLTGGAIDIGTPADKFTQPDAKAYEVMAQFPHLPAEIDGSQMQDAIPTIAVIAAFNETPVRFVGIANLR
VKECDRIRAVSLGLNEIREGLAHEEGDDLIVHADPSLAGQTVDASIDTFADHRIAMSFALAALKIGGIAIQNPACVAKTY
PGYWKALASLGVDYTEKESAAEPQH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=433, Percent_Identity=35.1039260969977, Blast_Score=186, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6320332, Length=454, Percent_Identity=35.0220264317181, Blast_Score=199, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 44700; Mature: 44700

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELTITPPGHPLSGKVEPPGSKSITNRALLLAGLAKGKSHLSGALKSDDTLYMAEALRE
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHEEHHHHCCHHHHCCCCCCCCCHHHHHHHHH
MGVKVTEPDATTFVVEGTGVLQQPEKPLFLGNAGTATRFLTAAGALVDGAVIIDGDEHMR
CCCEEECCCCEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCEEEECCHHHHH
KRPILPLVQALRALGVEADAPTGCPPVTVRGKGMGFPKGSVTIDANLSSQYVSALLMAAA
HCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHH
CGDKPVDIILKGEEIGAKGYIDLTTSAMEAFGAKVERVSNAIWRVHPTGYTATDFHIEPD
CCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCC
ASAATYLWGAELLTGGAIDIGTPADKFTQPDAKAYEVMAQFPHLPAEIDGSQMQDAIPTI
CCCEEEEEHHHHHCCCCEECCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCEE
AVIAAFNETPVRFVGIANLRVKECDRIRAVSLGLNEIREGLAHEEGDDLIVHADPSLAGQ
EEEEECCCCCEEEEEECCCCHHHCCHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCC
TVDASIDTFADHRIAMSFALAALKIGGIAIQNPACVAKTYPGYWKALASLGVDYTEKESA
EECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCHHHHHHHHCCCCCCCCCCC
AEPQH
CCCCC
>Mature Secondary Structure
MIELTITPPGHPLSGKVEPPGSKSITNRALLLAGLAKGKSHLSGALKSDDTLYMAEALRE
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHEEHHHHCCHHHHCCCCCCCCCHHHHHHHHH
MGVKVTEPDATTFVVEGTGVLQQPEKPLFLGNAGTATRFLTAAGALVDGAVIIDGDEHMR
CCCEEECCCCEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCEEEECCHHHHH
KRPILPLVQALRALGVEADAPTGCPPVTVRGKGMGFPKGSVTIDANLSSQYVSALLMAAA
HCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHH
CGDKPVDIILKGEEIGAKGYIDLTTSAMEAFGAKVERVSNAIWRVHPTGYTATDFHIEPD
CCCCCEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCC
ASAATYLWGAELLTGGAIDIGTPADKFTQPDAKAYEVMAQFPHLPAEIDGSQMQDAIPTI
CCCEEEEEHHHHHCCCCEECCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCEE
AVIAAFNETPVRFVGIANLRVKECDRIRAVSLGLNEIREGLAHEEGDDLIVHADPSLAGQ
EEEEECCCCCEEEEEECCCCHHHCCHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCC
TVDASIDTFADHRIAMSFALAALKIGGIAIQNPACVAKTYPGYWKALASLGVDYTEKESA
EECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCHHHHHHHHCCCCCCCCCCC
AEPQH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA