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The map label for this gene is rlmL [H]

Identifier: 15887690

GI number: 15887690

Start: 331152

End: 332081

Strand: Direct

Name: rlmL [H]

Synonym: Atu0340

Alternate gene names: 15887690

Gene position: 331152-332081 (Clockwise)

Preceding gene: 159184264

Following gene: 159184265

Centisome position: 11.65

GC content: 60.97

Gene sequence:

>930_bases
ATGCAGCGCACCGGTGAACTGCCCGCAGAACACGTCCCTGTCATTCTGGAATCGAGCGGCGCGGGTGATTTTCACCTGAT
CGACAGTGGTAACGGCCTGAAGCTTGAACAATATGGCGATTACCGCGTCGTTCGTCCCGAGGCGCAGGCGCTGTGGCGGC
CGTTGGTTCCCGACCGCGTATGGCAGAATGCCGACGCCATTTTTACCGGCGATACGGATGAGGACGGCATGGGCCGCTGG
CGTTTTCCGAAGGAAGCGCTTGGCGAAACCTGGCCTCTCTCCCTGCTGGGGGTTGAATTTCTCGGTCGTTTCACGGCGTT
CCGGCATGTCGGCGTCTTTCCGGAGCAGATCGTGCATTGGGAATGGCTGAAAAATGCCGTGGAGACTGCCGACCGGCCGC
TGAAAGTGCTGAACCTCTTCGGTTACACCGGCGTCGCCTCGCTGGTTGCGGCGGCTGCTGGTGCTGAAGTCACCCATGTC
GACGCCTCCAAGAAGGCGATCGGCTGGGCGAAGGAGAACCAGGTGCTCGCCGGGCTGGAACAGGCGCCGATCCGCTGGAT
TTGTGAAGACGCCATGAAGTTCATCCAGCGGGAAGAACGTCGTGGCAGCACTTACGACATCATTCTCACCGACCCGCCGA
AATTCGGCCGCGGCACTCACGGTGAGGTCTGGCAATTGTTCGACCATCTGCCGCTGATGCTTGATATCTGCCGGGAAATC
CTGTCGCCCAAGGCGCTCGGTCTGGTGCTGACGGCCTATTCCATCCGGGCCAGCTTCTATTCGATGCATGAGCTGATGCG
CGAAACCATGCGCGGTGCCGGCGGTGTTGTCGCATCCGGTGAACTGGTCATTCGCGAGGCGGGGCTTGACGGCAAGACGC
CGGGCCGCGTGCTTTCCACATCGCTATTCAGCCGTTGGGAGCCGAAATGA

Upstream 100 bases:

>100_bases
AAAGCGCGAGCCCGATGCGGTGCGCACCGTGCAGAAAGCCGCGCCGAAGGAAAAAACCGTCGTAGCGGCTGCCGTTGAGC
AAGTCCCCGCGCGCGCAATT

Downstream 100 bases:

>100_bases
CGAAGGACATGCGCGAAAACATCACGCGCCGGGTTGGCCAGGTCAAGGAAGTGACGAGCCTTGCCAATCCCATCATCAAG
GACATCAAGGCGCTCACCCA

Product: SAM dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQRTGELPAEHVPVILESSGAGDFHLIDSGNGLKLEQYGDYRVVRPEAQALWRPLVPDRVWQNADAIFTGDTDEDGMGRW
RFPKEALGETWPLSLLGVEFLGRFTAFRHVGVFPEQIVHWEWLKNAVETADRPLKVLNLFGYTGVASLVAAAAGAEVTHV
DASKKAIGWAKENQVLAGLEQAPIRWICEDAMKFIQREERRGSTYDIILTDPPKFGRGTHGEVWQLFDHLPLMLDICREI
LSPKALGLVLTAYSIRASFYSMHELMRETMRGAGGVVASGELVIREAGLDGKTPGRVLSTSLFSRWEPK

Sequences:

>Translated_309_residues
MQRTGELPAEHVPVILESSGAGDFHLIDSGNGLKLEQYGDYRVVRPEAQALWRPLVPDRVWQNADAIFTGDTDEDGMGRW
RFPKEALGETWPLSLLGVEFLGRFTAFRHVGVFPEQIVHWEWLKNAVETADRPLKVLNLFGYTGVASLVAAAAGAEVTHV
DASKKAIGWAKENQVLAGLEQAPIRWICEDAMKFIQREERRGSTYDIILTDPPKFGRGTHGEVWQLFDHLPLMLDICREI
LSPKALGLVLTAYSIRASFYSMHELMRETMRGAGGVVASGELVIREAGLDGKTPGRVLSTSLFSRWEPK
>Mature_309_residues
MQRTGELPAEHVPVILESSGAGDFHLIDSGNGLKLEQYGDYRVVRPEAQALWRPLVPDRVWQNADAIFTGDTDEDGMGRW
RFPKEALGETWPLSLLGVEFLGRFTAFRHVGVFPEQIVHWEWLKNAVETADRPLKVLNLFGYTGVASLVAAAAGAEVTHV
DASKKAIGWAKENQVLAGLEQAPIRWICEDAMKFIQREERRGSTYDIILTDPPKFGRGTHGEVWQLFDHLPLMLDICREI
LSPKALGLVLTAYSIRASFYSMHELMRETMRGAGGVVASGELVIREAGLDGKTPGRVLSTSLFSRWEPK

Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]

COG id: COG1092

COG function: function code R; Predicted SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR000241
- InterPro:   IPR017244
- InterPro:   IPR019614
- InterPro:   IPR004114 [H]

Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]

EC number: =2.1.1.173 [H]

Molecular weight: Translated: 34439; Mature: 34439

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTGELPAEHVPVILESSGAGDFHLIDSGNGLKLEQYGDYRVVRPEAQALWRPLVPDRV
CCCCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEEECCCEEEECCCHHHHHCCCCCHHH
WQNADAIFTGDTDEDGMGRWRFPKEALGETWPLSLLGVEFLGRFTAFRHVGVFPEQIVHW
HCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
EWLKNAVETADRPLKVLNLFGYTGVASLVAAAAGAEVTHVDASKKAIGWAKENQVLAGLE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCHHHHCHH
QAPIRWICEDAMKFIQREERRGSTYDIILTDPPKFGRGTHGEVWQLFDHLPLMLDICREI
HCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSPKALGLVLTAYSIRASFYSMHELMRETMRGAGGVVASGELVIREAGLDGKTPGRVLST
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCCCHHHHH
SLFSRWEPK
HHHHCCCCC
>Mature Secondary Structure
MQRTGELPAEHVPVILESSGAGDFHLIDSGNGLKLEQYGDYRVVRPEAQALWRPLVPDRV
CCCCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEEECCCEEEECCCHHHHHCCCCCHHH
WQNADAIFTGDTDEDGMGRWRFPKEALGETWPLSLLGVEFLGRFTAFRHVGVFPEQIVHW
HCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
EWLKNAVETADRPLKVLNLFGYTGVASLVAAAAGAEVTHVDASKKAIGWAKENQVLAGLE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCHHHHCHH
QAPIRWICEDAMKFIQREERRGSTYDIILTDPPKFGRGTHGEVWQLFDHLPLMLDICREI
HCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSPKALGLVLTAYSIRASFYSMHELMRETMRGAGGVVASGELVIREAGLDGKTPGRVLST
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCCCCHHHHH
SLFSRWEPK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA