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The map label for this gene is bacA

Identifier: 15887643

GI number: 15887643

Start: 288790

End: 289596

Strand: Direct

Name: bacA

Synonym: Atu0294

Alternate gene names: 15887643

Gene position: 288790-289596 (Clockwise)

Preceding gene: 15887629

Following gene: 159184244

Centisome position: 10.16

GC content: 58.36

Gene sequence:

>807_bases
ATGGGTGACCAATCGATCATCAGCGCGCTTTTGCTGGGCATTATCGAGGGTCTGACGGAGTTTATTCCCGTTTCCTCCAC
GGCGCATGTGCTGCTGGCCGGGCATTTCCTTGGCTTTAAATCGCCGGGCAATACCTTTGCCGTCCTCATCCAGCTCGGTG
CGATCCTCGCAATCCTTCTCGTTTATTTTCAAAAGCTTGTATCGATCGCCGTGGCGATGCCGACAAGTGCCAAGGCGCGC
CGTTTTGTGCTGGCGGTTCTCGTCGCTTTCCTGCCGGCGGCGGTGATCGGCGCTCTCGCGCATGACTTCATCAAGACGGT
GCTGTTCGAAACGCCGATGCTCATTTGTGTCGTGTTGATCATTGGTGGATTCATTTTGCTTGCGGTCGACCGGATGCCGC
TGAAACCAAAATATACCGACATTATGGATTACCCGCCGTCGCTCGCCTTCAAGATCGGCCTTTTCCAGTGCCTTGCGATG
ATTCCCGGCACCTCGCGGTCCGGCGCCACCATTGTCGGCGCGCTGCTGATGGGCACGGACAAGCGCTCCGCCGCCGAGTT
TTCGTTTTTTCTGGCCATGCCGACCATGCTTGGCGCGTTTGTGCTCGACCTCTACAAGAACCGCGATGCGCTGAGCTTCG
ATGATAGCGCCTTGATTGCCGTGGGGTTTGTGGCCGCCTTCGTGTCCGGCCTCTTCGTCGTGCGCTCGCTGCTGGATTTC
GTGTCGCGACGTGGGTTTGCGCCCTTTGCCTGGTGGCGCATCGTCATCGGTGCGCTCGGTCTCGTCGCACTTCTGGTTAT
CGGCTGA

Upstream 100 bases:

>100_bases
TTTCGCTTCATCAAGACGCTATAAGAGCTTGGCTACTTTAAAACAAGTTTAACGCAATTGCTTTCCATTCACGCTTTCCC
CCTTAAAAGAAGGATACCTC

Downstream 100 bases:

>100_bases
CCCGCAGTTTCATATCGACCGAAAAACAAAAAAGCGCCCCGGAGAACCGGCGGCGCTTTTTTTAAACCTGTAAAGGCCGA
TCAGTTGGCGCTGATCGAAG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MGDQSIISALLLGIIEGLTEFIPVSSTAHVLLAGHFLGFKSPGNTFAVLIQLGAILAILLVYFQKLVSIAVAMPTSAKAR
RFVLAVLVAFLPAAVIGALAHDFIKTVLFETPMLICVVLIIGGFILLAVDRMPLKPKYTDIMDYPPSLAFKIGLFQCLAM
IPGTSRSGATIVGALLMGTDKRSAAEFSFFLAMPTMLGAFVLDLYKNRDALSFDDSALIAVGFVAAFVSGLFVVRSLLDF
VSRRGFAPFAWWRIVIGALGLVALLVIG

Sequences:

>Translated_268_residues
MGDQSIISALLLGIIEGLTEFIPVSSTAHVLLAGHFLGFKSPGNTFAVLIQLGAILAILLVYFQKLVSIAVAMPTSAKAR
RFVLAVLVAFLPAAVIGALAHDFIKTVLFETPMLICVVLIIGGFILLAVDRMPLKPKYTDIMDYPPSLAFKIGLFQCLAM
IPGTSRSGATIVGALLMGTDKRSAAEFSFFLAMPTMLGAFVLDLYKNRDALSFDDSALIAVGFVAAFVSGLFVVRSLLDF
VSRRGFAPFAWWRIVIGALGLVALLVIG
>Mature_267_residues
GDQSIISALLLGIIEGLTEFIPVSSTAHVLLAGHFLGFKSPGNTFAVLIQLGAILAILLVYFQKLVSIAVAMPTSAKARR
FVLAVLVAFLPAAVIGALAHDFIKTVLFETPMLICVVLIIGGFILLAVDRMPLKPKYTDIMDYPPSLAFKIGLFQCLAMI
PGTSRSGATIVGALLMGTDKRSAAEFSFFLAMPTMLGAFVLDLYKNRDALSFDDSALIAVGFVAAFVSGLFVVRSLLDFV
SRRGFAPFAWWRIVIGALGLVALLVIG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=264, Percent_Identity=42.0454545454545, Blast_Score=201, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_AGRT5 (P58740)

Other databases:

- EMBL:   AE007869
- PIR:   AF2612
- PIR:   D97394
- RefSeq:   NP_353324.1
- STRING:   P58740
- GeneID:   1132332
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0294
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   IGHFIGF
- PhylomeDB:   P58740
- ProtClustDB:   PRK00281
- BioCyc:   ATUM176299-1:ATU0294-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28616; Mature: 28485

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb1466f4)-; HASH(0xcdc6144)-; HASH(0xcdcc858)-; HASH(0xcdcca38)-; HASH(0xcdcc9c0)-; HASH(0xcdc81b4)-; HASH(0xcdc11f0)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
GDQSIISALLLGIIEGLTEFIPVSSTAHVLLAGHFLGFKSPGNTFAVLIQLGAILAILL
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VYFQKLVSIAVAMPTSAKARRFVLAVLVAFLPAAVIGALAHDFIKTVLFETPMLICVVLI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGFILLAVDRMPLKPKYTDIMDYPPSLAFKIGLFQCLAMIPGTSRSGATIVGALLMGTD
HHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
KRSAAEFSFFLAMPTMLGAFVLDLYKNRDALSFDDSALIAVGFVAAFVSGLFVVRSLLDF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VSRRGFAPFAWWRIVIGALGLVALLVIG
HHHCCCCHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194