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The map label for this gene is hutC [H]

Identifier: 15887515

GI number: 15887515

Start: 165739

End: 166476

Strand: Direct

Name: hutC [H]

Synonym: Atu0160

Alternate gene names: 15887515

Gene position: 165739-166476 (Clockwise)

Preceding gene: 159184190

Following gene: 15887516

Centisome position: 5.83

GC content: 60.57

Gene sequence:

>738_bases
ATGAGGAGCACAGGCGCCGATCTTGAGGAAAAATCGCTGCACCAGCGCATCCGTAACGATGTCGAGCGCCACATCATGTC
TGGCGAATGGCCGCCGGGATATCGTATTCCCTTCGAACACGAGATGACCCGGCAATATGGCTGTTCGCGTATGACGGTGA
ACAAGGCGCTTGGTGAACTGGTGCAGCGTGGCCTGATTGAAAGACGCCGGCGTCTCGGCACCTTCGTTCGCCAGCCCCAT
GCGCAATCCGCCGTGTTGGAAATCCACGATATCGAGCGGGAGGTGCAGGCGATCGGTCTCGTTTACGGCTACCGTCTTGA
TAAACGACGGCTGCGCCCTGCAGGCAAGGAAGATGGCGCGGCCATGGCGCTTGCCGCCGATGCCCCGGTTCTGGAACTCA
CCTGCACGCATTTTGCCGGTGGCGTTCCCTTTTGCCTTGAGGAACGCATTGTTAATATCGCCGCCGTTCCCGAGGCGGAG
GGTACTGATTTTTCGCAGGTTGGGCCGGGAACCTGGCTGCTGAAGATGGTACCCTGGAGCGCCGCCGAACATCGCATCAG
CGCCGTTTCCGCAGATCGCAAAAACGCCGTGGCACTGGGTATTGCCTCCGGGGCGGCCTGTCTGGTCATCGATCGCCGCA
CCTGGCACGGGGCGGATTACATCACCCGCGTCCGGGTTACCTATCCCGGAGACCGGCATGCGCTGGTTGCGCAGTTTTCA
CCTTCCCAAAACAGCTGA

Upstream 100 bases:

>100_bases
GAGCTGCGGGCGAAACTCACGGAGGAAATACGCAGCGAGGCGATCGCCGCCGCTGCCCATGGATAGCTGATCCGGCAAAG
GGGAGGAGAGACGTATCGGG

Downstream 100 bases:

>100_bases
AACTGCTTGGGGCGATCAATTTTTTGCAAAGAAGAGTTTACGGGTCGTCTTTTGACAATATAATAGTTGTCAAAAGAACT
CAGGTTTATTATCGGAACGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRSTGADLEEKSLHQRIRNDVERHIMSGEWPPGYRIPFEHEMTRQYGCSRMTVNKALGELVQRGLIERRRRLGTFVRQPH
AQSAVLEIHDIEREVQAIGLVYGYRLDKRRLRPAGKEDGAAMALAADAPVLELTCTHFAGGVPFCLEERIVNIAAVPEAE
GTDFSQVGPGTWLLKMVPWSAAEHRISAVSADRKNAVALGIASGAACLVIDRRTWHGADYITRVRVTYPGDRHALVAQFS
PSQNS

Sequences:

>Translated_245_residues
MRSTGADLEEKSLHQRIRNDVERHIMSGEWPPGYRIPFEHEMTRQYGCSRMTVNKALGELVQRGLIERRRRLGTFVRQPH
AQSAVLEIHDIEREVQAIGLVYGYRLDKRRLRPAGKEDGAAMALAADAPVLELTCTHFAGGVPFCLEERIVNIAAVPEAE
GTDFSQVGPGTWLLKMVPWSAAEHRISAVSADRKNAVALGIASGAACLVIDRRTWHGADYITRVRVTYPGDRHALVAQFS
PSQNS
>Mature_245_residues
MRSTGADLEEKSLHQRIRNDVERHIMSGEWPPGYRIPFEHEMTRQYGCSRMTVNKALGELVQRGLIERRRRLGTFVRQPH
AQSAVLEIHDIEREVQAIGLVYGYRLDKRRLRPAGKEDGAAMALAADAPVLELTCTHFAGGVPFCLEERIVNIAAVPEAE
GTDFSQVGPGTWLLKMVPWSAAEHRISAVSADRKNAVALGIASGAACLVIDRRTWHGADYITRVRVTYPGDRHALVAQFS
PSQNS

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27248; Mature: 27248

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTGADLEEKSLHQRIRNDVERHIMSGEWPPGYRIPFEHEMTRQYGCSRMTVNKALGEL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
VQRGLIERRRRLGTFVRQPHAQSAVLEIHDIEREVQAIGLVYGYRLDKRRLRPAGKEDGA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHCCCCCCCCCC
AMALAADAPVLELTCTHFAGGVPFCLEERIVNIAAVPEAEGTDFSQVGPGTWLLKMVPWS
EEEEECCCCEEEEEEHHHCCCCCHHHHHHHHEEEECCCCCCCCHHHCCCCEEEEEECCCC
AAEHRISAVSADRKNAVALGIASGAACLVIDRRTWHGADYITRVRVTYPGDRHALVAQFS
HHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEEECCCCCCEEEEEEC
PSQNS
CCCCC
>Mature Secondary Structure
MRSTGADLEEKSLHQRIRNDVERHIMSGEWPPGYRIPFEHEMTRQYGCSRMTVNKALGEL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
VQRGLIERRRRLGTFVRQPHAQSAVLEIHDIEREVQAIGLVYGYRLDKRRLRPAGKEDGA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHCCCCCCCCCC
AMALAADAPVLELTCTHFAGGVPFCLEERIVNIAAVPEAEGTDFSQVGPGTWLLKMVPWS
EEEEECCCCEEEEEEHHHCCCCCHHHHHHHHEEEECCCCCCCCHHHCCCCEEEEEECCCC
AAEHRISAVSADRKNAVALGIASGAACLVIDRRTWHGADYITRVRVTYPGDRHALVAQFS
HHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEEECCCCCCEEEEEEC
PSQNS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2203753 [H]