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The map label for this gene is accD

Identifier: 15887379

GI number: 15887379

Start: 17231

End: 18127

Strand: Direct

Name: accD

Synonym: Atu0020

Alternate gene names: 15887379

Gene position: 17231-18127 (Clockwise)

Preceding gene: 159184126

Following gene: 15887380

Centisome position: 0.61

GC content: 59.64

Gene sequence:

>897_bases
TTGAACTGGATCACCAATTACGTTCGGCCGCGGATCAATTCCATGCTTGGCCGCCGCCCGGAGGTTCCGGAGAACCTGTG
GATCAAGTGCCCGGAAACGGGTGAGATGGTCTTCCACAAGGATCTGGAGGACAACAAGTGGGTCATCCCGGCTTCCGGTT
ACCACATGAAGATGCCGGCCAAGGCGCGCCTTGCCGATCTTTTTGATGGTGGCATCTATGAGGCCTTGGCCCAGCCTAAA
GTGGCACAGGACCCGCTGAAATTCCGCGATTCCAAGAAATACACCGATCGCCTGCGCGACAGCCGCGCAAAGACCGAGCA
GGAAGATACGATCCTTGCCGGCGTTGGTCTTCTGAAAGGCCTGAAGATCGTTGCCGTTGTGCATGAATTCCAGTTCATGG
CCGGCTCGCTCGGCATTGCCGCCGGCGAAGCGATCGTCAAGGCTTTCGAGCGCGCCATCTCGGAGCGTTGCCCGCTCGTC
ATGTTCCCGGCCTCGGGTGGCGCCCGTATGCAGGAAGGCATTCTGTCGCTGATGCAACTACCGCGCACCACGGTTGCGGT
GAATATGCTGAAAGAGGCAGGCATGCCGTATATCGTGGTTCTGACCAACCCGACCACGGGCGGTGTCACGGCTTCCTACG
CCATGCTGGGCGATGTCCATATTGCCGAGCCGGGCGCGGAAATCTGCTTTGCCGGCAAGCGTGTCATCGAGCAGACCATT
CGCGAAAAGCTGCCGGAAGGCTTCCAGACCTCGGAATACCTGCTGGAACACGGCATGGTGGATATGGTCATCGATCGTCG
CGAAATCCCGGACACGCTGGCCAGCATGCTCAAGATCATGACCAAGGCGCCTGCCGATAACGCGAACGCCGTCGTTCCGC
TGGCCGCTTCGGCCTGA

Upstream 100 bases:

>100_bases
GCCGGCAGTTACGACGCTGGTAAAAGGACTTTCAACGGGCGTGCGTGCATCGCGCCTCGCCGCTGCGGAATAAGCGCGCG
GCCCAGTCAGGAGTAGACAG

Downstream 100 bases:

>100_bases
GGAAAAAAATATGTCGCCCGGAGGCATAAACTGCTTTCGGGATGATGCTATACGTTGCCTGATTTCATTTTTGGGGCAGC
GGACAAATGGCAAACAAAAC

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNWITNYVRPRINSMLGRRPEVPENLWIKCPETGEMVFHKDLEDNKWVIPASGYHMKMPAKARLADLFDGGIYEALAQPK
VAQDPLKFRDSKKYTDRLRDSRAKTEQEDTILAGVGLLKGLKIVAVVHEFQFMAGSLGIAAGEAIVKAFERAISERCPLV
MFPASGGARMQEGILSLMQLPRTTVAVNMLKEAGMPYIVVLTNPTTGGVTASYAMLGDVHIAEPGAEICFAGKRVIEQTI
REKLPEGFQTSEYLLEHGMVDMVIDRREIPDTLASMLKIMTKAPADNANAVVPLAASA

Sequences:

>Translated_298_residues
MNWITNYVRPRINSMLGRRPEVPENLWIKCPETGEMVFHKDLEDNKWVIPASGYHMKMPAKARLADLFDGGIYEALAQPK
VAQDPLKFRDSKKYTDRLRDSRAKTEQEDTILAGVGLLKGLKIVAVVHEFQFMAGSLGIAAGEAIVKAFERAISERCPLV
MFPASGGARMQEGILSLMQLPRTTVAVNMLKEAGMPYIVVLTNPTTGGVTASYAMLGDVHIAEPGAEICFAGKRVIEQTI
REKLPEGFQTSEYLLEHGMVDMVIDRREIPDTLASMLKIMTKAPADNANAVVPLAASA
>Mature_298_residues
MNWITNYVRPRINSMLGRRPEVPENLWIKCPETGEMVFHKDLEDNKWVIPASGYHMKMPAKARLADLFDGGIYEALAQPK
VAQDPLKFRDSKKYTDRLRDSRAKTEQEDTILAGVGLLKGLKIVAVVHEFQFMAGSLGIAAGEAIVKAFERAISERCPLV
MFPASGGARMQEGILSLMQLPRTTVAVNMLKEAGMPYIVVLTNPTTGGVTASYAMLGDVHIAEPGAEICFAGKRVIEQTI
REKLPEGFQTSEYLLEHGMVDMVIDRREIPDTLASMLKIMTKAPADNANAVVPLAASA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=290, Percent_Identity=47.5862068965517, Blast_Score=275, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_AGRT5 (A9CKT0)

Other databases:

- EMBL:   AE007869
- PIR:   AE2579
- PIR:   D97361
- RefSeq:   NP_353060.1
- ProteinModelPortal:   A9CKT0
- SMR:   A9CKT0
- STRING:   A9CKT0
- GeneID:   1132058
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0020
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- PhylomeDB:   A9CKT0
- ProtClustDB:   PRK05654
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32788; Mature: 32788

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWITNYVRPRINSMLGRRPEVPENLWIKCPETGEMVFHKDLEDNKWVIPASGYHMKMPA
CCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEECCCCCCCEEEECCCCEEECCH
KARLADLFDGGIYEALAQPKVAQDPLKFRDSKKYTDRLRDSRAKTEQEDTILAGVGLLKG
HHHHHHHHCCHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LKIVAVVHEFQFMAGSLGIAAGEAIVKAFERAISERCPLVMFPASGGARMQEGILSLMQL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHC
PRTTVAVNMLKEAGMPYIVVLTNPTTGGVTASYAMLGDVHIAEPGAEICFAGKRVIEQTI
CHHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCEEECCCCHHHHHHHHHHHHHHH
REKLPEGFQTSEYLLEHGMVDMVIDRREIPDTLASMLKIMTKAPADNANAVVPLAASA
HHHCCCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC
>Mature Secondary Structure
MNWITNYVRPRINSMLGRRPEVPENLWIKCPETGEMVFHKDLEDNKWVIPASGYHMKMPA
CCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEECCCCCCCEEEECCCCEEECCH
KARLADLFDGGIYEALAQPKVAQDPLKFRDSKKYTDRLRDSRAKTEQEDTILAGVGLLKG
HHHHHHHHCCHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LKIVAVVHEFQFMAGSLGIAAGEAIVKAFERAISERCPLVMFPASGGARMQEGILSLMQL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHC
PRTTVAVNMLKEAGMPYIVVLTNPTTGGVTASYAMLGDVHIAEPGAEICFAGKRVIEQTI
CHHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCEEECCCCHHHHHHHHHHHHHHH
REKLPEGFQTSEYLLEHGMVDMVIDRREIPDTLASMLKIMTKAPADNANAVVPLAASA
HHHCCCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194