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The map label for this gene is purQ [H]

Identifier: 158423854

GI number: 158423854

Start: 2549951

End: 2550649

Strand: Direct

Name: purQ [H]

Synonym: AZC_2230

Alternate gene names: 158423854

Gene position: 2549951-2550649 (Clockwise)

Preceding gene: 158423853

Following gene: 158423855

Centisome position: 47.49

GC content: 69.1

Gene sequence:

>699_bases
ATGAAAGCAGCCGTTCTCCTCTTCCCTGGCTCCAATCGTGAAGGCGATGCGGCGCGCGCCCTTCGCCTCGTGACCGGACA
GGAGCCCAAGGTCGTCTGGCACGCGGAGAGCGAGCTGCCGCAGGGCACCGATCTCGTGGTGCTGCCCGGCGGCTTCTCCT
ATGGCGATTATCTGCGCTGCGGCGCCATCGCCGCCCGCGCCAACATCATGGACGCGGTGCGCGCCCATGCTGCCCGCGGC
GGCCTCGTCATCGGCATCTGCAACGGCTTCCAGATCCTCTGCGAGGCCGGCCTGCTGCCGGGCGTGCTGGTGCGCAACGC
CAAGCTGCGCTTCGTCTGCCGCGAGGTGTTCCTGCGCGTCGAGCGGGCCGACACGGCCTTCACGAAGGCCTATCGCAAGG
GCGACCTCATCCGCGTGCCGGTGGCGCACGGCGAGGGCAACTACACCGCCGATCCGGCGACCATCCAGCGCCTGGAAGGC
GAAGGCCGGGTGGCCTTCCGCTATGCCCGCGCCGACGGCCAGATCGACGAGACCGATGGCCCGAACGGCGCCATCAACGG
CATCGCCGGCATCTATTCCGAGAAGCTGAACGTGCTCGGCATGATGCCGCATCCCGAGAACTATGTGGACCCCGTGGTGG
GGCCGACGGACGGGCGCGGCCTGTTCGAAAGCCTTGCCGGCGCGCTCAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CCAACTGTTCCATTCCGTTTTCCCGCAAGGCCCGAAGCAGGGTCGGCCCGTTGCCTCGCAGCGTGTCGCCCCCTGCCGGC
GCGAGACCCGCTGAGAGCCC

Downstream 100 bases:

>100_bases
CGCGCCTGCGGCGCGCTTCCGCGCCCGGCGCCTTTCCCAAAGACCTGGATTGATCGGACGGACGAACGTGATCCCGAACA
CCCCCAGCATCACCCCGGAA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKAAVLLFPGSNREGDAARALRLVTGQEPKVVWHAESELPQGTDLVVLPGGFSYGDYLRCGAIAARANIMDAVRAHAARG
GLVIGICNGFQILCEAGLLPGVLVRNAKLRFVCREVFLRVERADTAFTKAYRKGDLIRVPVAHGEGNYTADPATIQRLEG
EGRVAFRYARADGQIDETDGPNGAINGIAGIYSEKLNVLGMMPHPENYVDPVVGPTDGRGLFESLAGALKAA

Sequences:

>Translated_232_residues
MKAAVLLFPGSNREGDAARALRLVTGQEPKVVWHAESELPQGTDLVVLPGGFSYGDYLRCGAIAARANIMDAVRAHAARG
GLVIGICNGFQILCEAGLLPGVLVRNAKLRFVCREVFLRVERADTAFTKAYRKGDLIRVPVAHGEGNYTADPATIQRLEG
EGRVAFRYARADGQIDETDGPNGAINGIAGIYSEKLNVLGMMPHPENYVDPVVGPTDGRGLFESLAGALKAA
>Mature_232_residues
MKAAVLLFPGSNREGDAARALRLVTGQEPKVVWHAESELPQGTDLVVLPGGFSYGDYLRCGAIAARANIMDAVRAHAARG
GLVIGICNGFQILCEAGLLPGVLVRNAKLRFVCREVFLRVERADTAFTKAYRKGDLIRVPVAHGEGNYTADPATIQRLEG
EGRVAFRYARADGQIDETDGPNGAINGIAGIYSEKLNVLGMMPHPENYVDPVVGPTDGRGLFESLAGALKAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=176, Percent_Identity=35.7954545454545, Blast_Score=82, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321498, Length=179, Percent_Identity=31.2849162011173, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582111, Length=197, Percent_Identity=33.502538071066, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582109, Length=197, Percent_Identity=33.502538071066, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17137292, Length=197, Percent_Identity=33.502538071066, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24716; Mature: 24716

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVLLFPGSNREGDAARALRLVTGQEPKVVWHAESELPQGTDLVVLPGGFSYGDYLRC
CCEEEEEECCCCCCCCHHHHHHEECCCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHH
GAIAARANIMDAVRAHAARGGLVIGICNGFQILCEAGLLPGVLVRNAKLRFVCREVFLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
ERADTAFTKAYRKGDLIRVPVAHGEGNYTADPATIQRLEGEGRVAFRYARADGQIDETDG
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHEECCCCEEEEEEECCCCCCCCCCC
PNGAINGIAGIYSEKLNVLGMMPHPENYVDPVVGPTDGRGLFESLAGALKAA
CCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAAVLLFPGSNREGDAARALRLVTGQEPKVVWHAESELPQGTDLVVLPGGFSYGDYLRC
CCEEEEEECCCCCCCCHHHHHHEECCCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHH
GAIAARANIMDAVRAHAARGGLVIGICNGFQILCEAGLLPGVLVRNAKLRFVCREVFLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
ERADTAFTKAYRKGDLIRVPVAHGEGNYTADPATIQRLEGEGRVAFRYARADGQIDETDG
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHEECCCCEEEEEEECCCCCCCCCCC
PNGAINGIAGIYSEKLNVLGMMPHPENYVDPVVGPTDGRGLFESLAGALKAA
CCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]