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The map label for this gene is catE [H]

Identifier: 158423677

GI number: 158423677

Start: 2366368

End: 2367234

Strand: Direct

Name: catE [H]

Synonym: AZC_2053

Alternate gene names: 158423677

Gene position: 2366368-2367234 (Clockwise)

Preceding gene: 158423676

Following gene: 158423678

Centisome position: 44.07

GC content: 69.67

Gene sequence:

>867_bases
ATGACCGCAACCCTCGCCCCCTCTGCTCACGCGCCTGCAAGCGGCTTGTCGCTCGCCATGGGCCGGGTGGTGCTGACCGT
GCACGACCTCGCCGGCGTCGCCGCCTTCTATGAGCGTGCGGTCGGCCTTCACCGGCTGCGGGGGGATGGGGAACATGTCG
AACTCGGCGTGGGCGGTACCGTCCTCCTGGAACTGCGGCGGGACGCGGCTGCGCGCCGCTCCACCGCCCGCGAGGCGGGC
CTGTTCCATACGGCCTTCCTGCTGCCCAGCCGGGTGGATCTTGCCCGCTGGACGCATCACGCCATGGCCGACCGGGTGCC
GGTGGTCGGCGCCTCCGATCATGCGGTGAGCGAAGCCATCTATCTCACCGACCCGGAAGGCAACGGCGTGGAGATCTATG
CCGACCGCCCCGCCAGCGCGTGGCGCTGGGACAATGGCTCGATCCATATGGTCACAGAGGCCCTGCGGTTCGACACGCTC
ATGGCCGAGCCCGGCGCCGACACGCCCTGGCAGGGTTTTCCGGACGGCGCGGTGGTCGGTCACGTGCATCTGCAGGTGGG
CGCGGTGCCCACCGCCGAGGCCTTCTATGCCGGCGTGCTGGGCTTCGACATCACGACCCATTATCCCGGCGCGGCCTTCT
ATGCCGCCAATGGCTATCACCACCATCTGGCGACAAACATCTGGAACAGCCGGGGCGCGGCGGTCCGCACCTATCCGTCC
ACGGGCCTTGCGGAATTCACGCTGGTGGCGGGGCCGGACCGGATGGAGGGCATCCGGGCCCGTACGGGGGAAACGGGGCC
GGCCTTCAAGGTGACCGATCCCTGGGGGACAGTCGTGCGGATGATCGAGGACGGCGGCGCGCACTGA

Upstream 100 bases:

>100_bases
CGCGGGCCTCCTGGCTCTGGCGCTCATCGGTGACGGCGCCTTTGCCCTGAAGTCCACGCCGGTCGGCGCGCGCCGCTGAG
GCGCAACAGGAGGACGGACC

Downstream 100 bases:

>100_bases
CCGCGCAGCGGCACGAAAGGGCGAGAGACCGAACATGCTCGTGGATGGAAAATGGACCGCCGATTGGCAGCCGGTTCAAG
CGACCGACGCCAAGGGCGGT

Product: ring-cleavage extradiol dioxygenase

Products: NA

Alternate protein names: Catechol-induced ring cleavage extradiol dioxygenase [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTATLAPSAHAPASGLSLAMGRVVLTVHDLAGVAAFYERAVGLHRLRGDGEHVELGVGGTVLLELRRDAAARRSTAREAG
LFHTAFLLPSRVDLARWTHHAMADRVPVVGASDHAVSEAIYLTDPEGNGVEIYADRPASAWRWDNGSIHMVTEALRFDTL
MAEPGADTPWQGFPDGAVVGHVHLQVGAVPTAEAFYAGVLGFDITTHYPGAAFYAANGYHHHLATNIWNSRGAAVRTYPS
TGLAEFTLVAGPDRMEGIRARTGETGPAFKVTDPWGTVVRMIEDGGAH

Sequences:

>Translated_288_residues
MTATLAPSAHAPASGLSLAMGRVVLTVHDLAGVAAFYERAVGLHRLRGDGEHVELGVGGTVLLELRRDAAARRSTAREAG
LFHTAFLLPSRVDLARWTHHAMADRVPVVGASDHAVSEAIYLTDPEGNGVEIYADRPASAWRWDNGSIHMVTEALRFDTL
MAEPGADTPWQGFPDGAVVGHVHLQVGAVPTAEAFYAGVLGFDITTHYPGAAFYAANGYHHHLATNIWNSRGAAVRTYPS
TGLAEFTLVAGPDRMEGIRARTGETGPAFKVTDPWGTVVRMIEDGGAH
>Mature_287_residues
TATLAPSAHAPASGLSLAMGRVVLTVHDLAGVAAFYERAVGLHRLRGDGEHVELGVGGTVLLELRRDAAARRSTAREAGL
FHTAFLLPSRVDLARWTHHAMADRVPVVGASDHAVSEAIYLTDPEGNGVEIYADRPASAWRWDNGSIHMVTEALRFDTLM
AEPGADTPWQGFPDGAVVGHVHLQVGAVPTAEAFYAGVLGFDITTHYPGAAFYAANGYHHHLATNIWNSRGAAVRTYPST
GLAEFTLVAGPDRMEGIRARTGETGPAFKVTDPWGTVVRMIEDGGAH

Specific function: Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol [H]

COG id: COG2514

COG function: function code R; Predicted ring-cleavage extradiol dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.2 [H]

Molecular weight: Translated: 30674; Mature: 30543

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLAPSAHAPASGLSLAMGRVVLTVHDLAGVAAFYERAVGLHRLRGDGEHVELGVGGT
CCCCCCCCCCCCCCCHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCE
VLLELRRDAAARRSTAREAGLFHTAFLLPSRVDLARWTHHAMADRVPVVGASDHAVSEAI
EEEEEHHHHHHHHHHHHHHCCEEEEHHCCCCHHHHHHHHHHHHCCCCEECCCCCHHCEEE
YLTDPEGNGVEIYADRPASAWRWDNGSIHMVTEALRFDTLMAEPGADTPWQGFPDGAVVG
EEECCCCCCEEEEECCCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEE
HVHLQVGAVPTAEAFYAGVLGFDITTHYPGAAFYAANGYHHHLATNIWNSRGAAVRTYPS
EEEEEECCCCCHHHHHHHHHCCEEECCCCCEEEEECCCEEHHHHHHHHCCCCCEEEECCC
TGLAEFTLVAGPDRMEGIRARTGETGPAFKVTDPWGTVVRMIEDGGAH
CCCEEEEEEECCCHHCCHHHCCCCCCCEEEEECCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TATLAPSAHAPASGLSLAMGRVVLTVHDLAGVAAFYERAVGLHRLRGDGEHVELGVGGT
CCCCCCCCCCCCCCHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCE
VLLELRRDAAARRSTAREAGLFHTAFLLPSRVDLARWTHHAMADRVPVVGASDHAVSEAI
EEEEEHHHHHHHHHHHHHHCCEEEEHHCCCCHHHHHHHHHHHHCCCCEECCCCCHHCEEE
YLTDPEGNGVEIYADRPASAWRWDNGSIHMVTEALRFDTLMAEPGADTPWQGFPDGAVVG
EEECCCCCCEEEEECCCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEE
HVHLQVGAVPTAEAFYAGVLGFDITTHYPGAAFYAANGYHHHLATNIWNSRGAAVRTYPS
EEEEEECCCCCHHHHHHHHHCCEEECCCCCEEEEECCCEEHHHHHHHHCCCCCEEEECCC
TGLAEFTLVAGPDRMEGIRARTGETGPAFKVTDPWGTVVRMIEDGGAH
CCCEEEEEEECCCHHCCHHHCCCCCCCEEEEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377 [H]