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The map label for this gene is lysR [C]

Identifier: 158423675

GI number: 158423675

Start: 2364879

End: 2365826

Strand: Direct

Name: lysR [C]

Synonym: AZC_2051

Alternate gene names: 158423675

Gene position: 2364879-2365826 (Clockwise)

Preceding gene: 158423673

Following gene: 158423676

Centisome position: 44.04

GC content: 66.14

Gene sequence:

>948_bases
TTGCCCGTGTCTCACGGGGTGATCTGTGGTGGTGTGATGGAGCGTCTGACCTGTGACCGCATGTTCGTGGCCGTGCTGGA
CACCGGCAGCTTCTCCGCGGCTGCCGAAAGGCTGGGAACCAGCAGCGGGCAGGCCTCCAAGCTTGTCTCGCGTCTGGAGA
CGGAGCTTGGCGTGCAACTGCTCAAGCGCACCACGCGGGCGCTCTCGCCCACGGAAGTGGGGCAGGCATATTATGAGCGC
ATCAAGCCGCTGCTCGATGAATTCGAGGCCCTCGATGCCTCGGTACGCAATGCCTCCGGCGCGCCGGCGGGGCGGCTGCG
GCTCAGCGCGCCCATGTCGTTCGGGCACATCCAGCTCATGCCGCTGCTGCTCGATTTTGCCCGCGCCTTTCCGCAGATCC
AGCTCAACGTGAGCTTCTCTGATCGGCTGGTGAACGTGGTGGATGAAGGCTTTGACGCCGCCATCCGTATCGGATCCCCG
AGGGATTCGAGCCTGATCGCGCGCAAGCTGTGCGACTCGCAGATCATGTGGCTGGCCTCGCCCGCGTATCTCGCCTCCCA
TGGAACACCGCAGACACCGCAGGACCTTGTCCGGCATGCCTGCATCATCGACGACAATTTCCCCGAGCCGCTGGTCTGGC
GGTTCCAGACACCCGATGGCGTCGGCGATGCGGTCACGGTCTCCGGCCGCATGCGCTTTTCCAGCGGCGAAGCGTGCCTC
GCCGCAGCCGAGGCCGGGCTCGGCATCGCCCGCATGCCCACCTTCATCGCCGGGCCCAAGCTCAAGGCCGGGACGGTGGT
GCCGCTCTTTCGCGATTTGATGCCACCGGCGCGGGGCGTCTATGCGCTCTATCCGCCGGGGCGCCATCTCGCCGTGAAAG
TGCGCGCGCTCGTCGATTTCCTCGCCAATTGCTATCGGGGCCAGCCCGAGTGGGACCGTGGCTGGTAG

Upstream 100 bases:

>100_bases
TCCTAGTCCGCGCGCGAGGGCGAGGAAAGCAATAAAGCTTCCATCCGCACCGGGAATTTCTTCGGTTCCATGATGCGGAC
CTGGATGCGATCTCTGGTGG

Downstream 100 bases:

>100_bases
GTCGATCTCTTCCATTCTGGAAGGAAACTGTCCCGTCTCGCCCGCTTAATCGCTCCGCTTCGGAAGAGGATAGTCCGCTC
ATCTTCACTTCCAGCGGATT

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPVSHGVICGGVMERLTCDRMFVAVLDTGSFSAAAERLGTSSGQASKLVSRLETELGVQLLKRTTRALSPTEVGQAYYER
IKPLLDEFEALDASVRNASGAPAGRLRLSAPMSFGHIQLMPLLLDFARAFPQIQLNVSFSDRLVNVVDEGFDAAIRIGSP
RDSSLIARKLCDSQIMWLASPAYLASHGTPQTPQDLVRHACIIDDNFPEPLVWRFQTPDGVGDAVTVSGRMRFSSGEACL
AAAEAGLGIARMPTFIAGPKLKAGTVVPLFRDLMPPARGVYALYPPGRHLAVKVRALVDFLANCYRGQPEWDRGW

Sequences:

>Translated_315_residues
MPVSHGVICGGVMERLTCDRMFVAVLDTGSFSAAAERLGTSSGQASKLVSRLETELGVQLLKRTTRALSPTEVGQAYYER
IKPLLDEFEALDASVRNASGAPAGRLRLSAPMSFGHIQLMPLLLDFARAFPQIQLNVSFSDRLVNVVDEGFDAAIRIGSP
RDSSLIARKLCDSQIMWLASPAYLASHGTPQTPQDLVRHACIIDDNFPEPLVWRFQTPDGVGDAVTVSGRMRFSSGEACL
AAAEAGLGIARMPTFIAGPKLKAGTVVPLFRDLMPPARGVYALYPPGRHLAVKVRALVDFLANCYRGQPEWDRGW
>Mature_314_residues
PVSHGVICGGVMERLTCDRMFVAVLDTGSFSAAAERLGTSSGQASKLVSRLETELGVQLLKRTTRALSPTEVGQAYYERI
KPLLDEFEALDASVRNASGAPAGRLRLSAPMSFGHIQLMPLLLDFARAFPQIQLNVSFSDRLVNVVDEGFDAAIRIGSPR
DSSLIARKLCDSQIMWLASPAYLASHGTPQTPQDLVRHACIIDDNFPEPLVWRFQTPDGVGDAVTVSGRMRFSSGEACLA
AAEAGLGIARMPTFIAGPKLKAGTVVPLFRDLMPPARGVYALYPPGRHLAVKVRALVDFLANCYRGQPEWDRGW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=34.4709897610922, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=31.4189189189189, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=30.5555555555556, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=33.4494773519164, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=29.2253521126761, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=29.0102389078498, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=27.7397260273973, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789173, Length=266, Percent_Identity=28.1954887218045, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788706, Length=278, Percent_Identity=28.0575539568345, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790011, Length=254, Percent_Identity=27.5590551181102, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786448, Length=294, Percent_Identity=27.5510204081633, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=24.9146757679181, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=133, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=25.7309941520468, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34170; Mature: 34039

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSHGVICGGVMERLTCDRMFVAVLDTGSFSAAAERLGTSSGQASKLVSRLETELGVQL
CCCCCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LKRTTRALSPTEVGQAYYERIKPLLDEFEALDASVRNASGAPAGRLRLSAPMSFGHIQLM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHH
PLLLDFARAFPQIQLNVSFSDRLVNVVDEGFDAAIRIGSPRDSSLIARKLCDSQIMWLAS
HHHHHHHHHCCEEEEEECHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCHHHHHHCC
PAYLASHGTPQTPQDLVRHACIIDDNFPEPLVWRFQTPDGVGDAVTVSGRMRFSSGEACL
CHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECEEEECCCCHHH
AAAEAGLGIARMPTFIAGPKLKAGTVVPLFRDLMPPARGVYALYPPGRHLAVKVRALVDF
HHHHHCCCHHHCCHHHCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHH
LANCYRGQPEWDRGW
HHHHHCCCCCCCCCC
>Mature Secondary Structure 
PVSHGVICGGVMERLTCDRMFVAVLDTGSFSAAAERLGTSSGQASKLVSRLETELGVQL
CCCCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LKRTTRALSPTEVGQAYYERIKPLLDEFEALDASVRNASGAPAGRLRLSAPMSFGHIQLM
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHH
PLLLDFARAFPQIQLNVSFSDRLVNVVDEGFDAAIRIGSPRDSSLIARKLCDSQIMWLAS
HHHHHHHHHCCEEEEEECHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCHHHHHHCC
PAYLASHGTPQTPQDLVRHACIIDDNFPEPLVWRFQTPDGVGDAVTVSGRMRFSSGEACL
CHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECEEEECCCCHHH
AAAEAGLGIARMPTFIAGPKLKAGTVVPLFRDLMPPARGVYALYPPGRHLAVKVRALVDF
HHHHHCCCHHHCCHHHCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHH
LANCYRGQPEWDRGW
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]