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The map label for this gene is fabG [H]

Identifier: 158423604

GI number: 158423604

Start: 2283239

End: 2283946

Strand: Direct

Name: fabG [H]

Synonym: AZC_1980

Alternate gene names: 158423604

Gene position: 2283239-2283946 (Clockwise)

Preceding gene: 158423603

Following gene: 158423605

Centisome position: 42.52

GC content: 70.06

Gene sequence:

>708_bases
ATGAATGCTGTCTCGTCTGAAGGTGGCGGGCGCGTGCCACACGCGCTCGTCACCGGCGTGAGCTCCGGCATCGGCGCGGA
GATCGCGAGCCAACTGCTGGCGCTTGGATGGCGTGTGACCGGCTTCAGCCGCGGACAGCCCGGGCAGGAACATCCGGCGC
TCACGCATGTCCCGGTGGACATCTCCAAGCGCGGCGCACTGGCGGAGGCCCTGCTGGATCTGGCGCCGCTCGACGCCCTC
ATCCATGCCGCCGGCATATTGCGCGTAGGGACGCTGGGGGCGTTGGACCCGGAGAACGGCAAGGCCATGTGGCGCCTCCA
TGTGGATGCGGCCGAGCAGATGATCGAAGCCACGGTGGCCGCGATGCCCGAGGGCGCGCGCATCGTCCTGATCGGCAGCC
GCACGGCGGCCGGCTCGGCCGGGCGGGCTCAGTATGCGGCGACCAAGGCGGCGCTGGTCGGCATGGCCCGCTCGTTCGCC
ATCGAACTCGCCCCGCGTCGGATCACCGTGAACGTGATCGCGCCCGGTGCCACCGACACGCCCATGCTTCGGGACCCCAG
CCGCGCGTCCGTGACGCCGAAGATGCCGCCGATGGGCCGTCTCGTGCAGCCGAAGGAAGTGGCCTCGTTGGCAGCCTTCC
TGCTTTCGGACGGAGCCGCGAGCATCACCGGCCAGCAGATCGTCGTCTGCGGCGGCGCATCACTCTAA

Upstream 100 bases:

>100_bases
CCATCTCCGACTTCTCGAAGATCTATACCAACGATCTCATCAACGACATCAACAACTTCGACGTGGAGAAGATCCGCGCG
CAGGCGCGATCCTACGGCCA

Downstream 100 bases:

>100_bases
GGACAGGGCGCGAGATTCCGCGCCCTGTCTCTCGGTCGCTGCTGGCTGCCATCGGCGATTGCCTGTCCTTCTGCCGCAGG
CACCGCGGGGAGTTGCCGAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNAVSSEGGGRVPHALVTGVSSGIGAEIASQLLALGWRVTGFSRGQPGQEHPALTHVPVDISKRGALAEALLDLAPLDAL
IHAAGILRVGTLGALDPENGKAMWRLHVDAAEQMIEATVAAMPEGARIVLIGSRTAAGSAGRAQYAATKAALVGMARSFA
IELAPRRITVNVIAPGATDTPMLRDPSRASVTPKMPPMGRLVQPKEVASLAAFLLSDGAASITGQQIVVCGGASL

Sequences:

>Translated_235_residues
MNAVSSEGGGRVPHALVTGVSSGIGAEIASQLLALGWRVTGFSRGQPGQEHPALTHVPVDISKRGALAEALLDLAPLDAL
IHAAGILRVGTLGALDPENGKAMWRLHVDAAEQMIEATVAAMPEGARIVLIGSRTAAGSAGRAQYAATKAALVGMARSFA
IELAPRRITVNVIAPGATDTPMLRDPSRASVTPKMPPMGRLVQPKEVASLAAFLLSDGAASITGQQIVVCGGASL
>Mature_235_residues
MNAVSSEGGGRVPHALVTGVSSGIGAEIASQLLALGWRVTGFSRGQPGQEHPALTHVPVDISKRGALAEALLDLAPLDAL
IHAAGILRVGTLGALDPENGKAMWRLHVDAAEQMIEATVAAMPEGARIVLIGSRTAAGSAGRAQYAATKAALVGMARSFA
IELAPRRITVNVIAPGATDTPMLRDPSRASVTPKMPPMGRLVQPKEVASLAAFLLSDGAASITGQQIVVCGGASL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=32.0675105485232, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=205, Percent_Identity=27.3170731707317, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=30.5439330543933, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7705925, Length=230, Percent_Identity=27.8260869565217, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723750, Length=96, Percent_Identity=35.4166666666667, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=234, Percent_Identity=35.8974358974359, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=33.4710743801653, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.4110671936759, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI2367365, Length=226, Percent_Identity=33.6283185840708, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=30.1652892561983, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789208, Length=237, Percent_Identity=26.1603375527426, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1789378, Length=191, Percent_Identity=29.8429319371728, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=29.3877551020408, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=240, Percent_Identity=29.5833333333333, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=243, Percent_Identity=28.8065843621399, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643142, Length=232, Percent_Identity=29.3103448275862, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=239, Percent_Identity=31.7991631799163, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=26.3598326359833, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 23928; Mature: 23928

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVSSEGGGRVPHALVTGVSSGIGAEIASQLLALGWRVTGFSRGQPGQEHPALTHVPVD
CCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCEEECCCC
ISKRGALAEALLDLAPLDALIHAAGILRVGTLGALDPENGKAMWRLHVDAAEQMIEATVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
AMPEGARIVLIGSRTAAGSAGRAQYAATKAALVGMARSFAIELAPRRITVNVIAPGATDT
HCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEECCCCCC
PMLRDPSRASVTPKMPPMGRLVQPKEVASLAAFLLSDGAASITGQQIVVCGGASL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MNAVSSEGGGRVPHALVTGVSSGIGAEIASQLLALGWRVTGFSRGQPGQEHPALTHVPVD
CCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCEEECCCC
ISKRGALAEALLDLAPLDALIHAAGILRVGTLGALDPENGKAMWRLHVDAAEQMIEATVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
AMPEGARIVLIGSRTAAGSAGRAQYAATKAALVGMARSFAIELAPRRITVNVIAPGATDT
HCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEECCCCCC
PMLRDPSRASVTPKMPPMGRLVQPKEVASLAAFLLSDGAASITGQQIVVCGGASL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]