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The map label for this gene is dmsA [H]

Identifier: 158423498

GI number: 158423498

Start: 2147215

End: 2149665

Strand: Direct

Name: dmsA [H]

Synonym: AZC_1874

Alternate gene names: 158423498

Gene position: 2147215-2149665 (Clockwise)

Preceding gene: 158423491

Following gene: 158423499

Centisome position: 39.99

GC content: 63.53

Gene sequence:

>2451_bases
GTGTCTAATAACCCTGGGTTCTCAAAAGGCCGCCGGCTGCATATTGGACTGATCCAACCTCGGGCAGCAATATTGATGGA
CAGCTTTCATCGATCGACGCGGCACGCTGGCCGCGGCCTTGCCGAGCCTCAGATGCCTCGTAACCCTTCGATTGCCGCTG
GTGCCTCTCACGCTTCGCACTGGGGAAGTTTTTCTGCGCGTTGGGATGGGGACCGTGTTCAATTGACACCGCATCCCGAA
GATCCCGCTCCTTCTCCGATCCTGGGGAACTTCGCCGATGCCTTGCGCCATCAGGCGCGCATCCTTCGCCCAATGGTGCG
CCGGGGCTGGCTGGACCACGGACCCGGTCCCCGCCACCGGGACTTCTCAAACGATCTGGTGCCGGTCTCTTGGGAAACGG
CACTCAGTCTTGTGGCGACTGAGATCGCGCGCGTCCGCGACTCCTACGGGCCGGAGGCGGTCTACGGCGGCTCCTATGGC
TGGTCCAGCGCCGGCCGGTTTCATCACGCCCAAAGCCAGATTCACCGCTTCCACAACGTGGTGTGCGGCGGCTATGTGCG
GTCGGTCAATAGCTACAGTGCGGGCGCCTCTGCTGTCATCTTGCCACGCGTGATGGGACCTTTCGAGCCCCTGTCCCGTC
ACAATGTCACGTGGGACCAAATCTGCGCCCACACGGATATGGTGCTCGCCTTCGGCGGCATGCCGATCAAGAATTCCATG
ATCGCCAGCGGCGGCATCACCCGCCACGTGGAAGCCGACGCGATGGCTCGGGCGGCGGCGCGAGGCACCGAATTCTGGTC
GGTGAGCCCGTTGCGGGACGATATGCCCGAGGCGGCGGAAGCTCGCTGGTTGCCAATCCGTCCCGGAACCGACGTCGCAA
TGATGCTCGGGCTTGCACACACGCTGCTGACCGAAGCGTTATACGATAGCTCCTTTGTCGCGCGTTATTGCGTTGGCTTC
GAACGGTTCGCGTCGTATCTCACGGGCGAGGCCGACGGCCTGCCAAAGAGCGCGGACTGGGCAGCCGAGATTACAGGCAT
CGGTGCGGATGCCATGCGTATGCTCGCACGCCGGCTGGTGGAAGGGCGCAGCCTCATCACCGTGGCTCATTCCCTTCAGC
GGGCGCAGTTTGGAGAGCAGCCGGTCTGGATGGCTGCGACCCTCGCCGCCATGGTCGGTCAGATTGGTTTACCAGGGGGC
GGTTTCAACTATGCCCTTGGCGCCATGGGTCATACTGGTCGGCAAATCAACGCCGTTCCAATTCCCACTTTGCCGCAGGG
GCGAAACGGCGTCTCCACCTTCATTCCGGTCGCGCGTATCGCAGACATGCTTCTGAATCCGGGAGGTGTGTTCGCCTTCA
ATGGAGCAACATACGTTTATCCCCGCGTGCGCCTCATTCACTGGGCCGGGGGCAACCCCTTCCATCATCATCAGGATCTC
AACCGTCTGCGCCGTGCCTTCTCGGAGGCGGATACCATCATCGTCCAGGAGAGCGCTTGGACGCCAATGGCACGTTTCGC
TGACATCGTGCTGCCGGTCACGATGACACTGGAGCGCGAGGATATCGGCGCAGCGGCTACCGACCCGCGTCTGATCGCGA
TGCGTCAGGTGGCGCCCCCGATCGGGGAGGCTCGTGATGATTTTGTGATTTTCAGCGCTCTCGCCGCTCGCCTCGGCCTC
GAAGCCGCCTTCACGGAGGGACGCTCCGTGCGCGAGTGGCTTGCACATCTTTACGAGCAGACACAGGAAGCTTTGGAAAA
TGCTGGCCTGTTCGCCCCCTCCTTCGAGGAGTTCTGGGAGAGAGGCGAGATCCCCTTGCCTTCGGCGCCCGACGATGGCG
GTCTGCTGCGGGCCTTTCGCGCCGATCCGCAGGCCGCGCCTCTCCCAACGCCAAGCGGACGCATCGAGATTTTCTCGGAG
ACCATTGCCGGCTTCGGTTACGACGATTGCCCTGGGCATCCGACCTGGCTGCCTTCGGAAGAACAGCCCTCCGCCCAGAC
ACCACTGACACTGGTGGCCAACCAGCCCGCCACGCGGTTGCACAGCCAATTGGACTTTGCGGCTCATAGCCAGTCACACA
AGCAGAAGGGCAGGGAGGTCGTTCGTATCAATCCGAACGATGCGCTCGAGCGGGGCATCGGAGACGGCGACCTTGTACGC
CTTTTCAACGCGCGCGGCGCCTGCGTGGCCAGCGCGCGCCTGAGCGCCGATGTGATGCCGGGCGTGCTGCACCTGCCAAC
CGGCGCTTGGTACGATCCCGAGGACGAGGCACCGGAGGGGCCGCTCTGCGTGCATGGCAATCCCAACGTCCTGACGCGGG
ATGTTGGCACCTCACAATTGGCGCAGGCCTGCTGCGGCCAGGTCACTGTGGTGGATATCGCCCGGCATGATCGACCAGTG
CGCGAAGTGCTGGCACATCGCCCGCCCGCGTTCGCGGAGGCCGCGCCATGA

Upstream 100 bases:

>100_bases
CGGCGGCCCGCCTGTAGTTCAGCTCCTCGGCGGTGGCGAGGAAATAACGTAGGTGGCGCAGCTCGATCTGTTCGGCGCCC
TGCCTGCCTTGGAATGACAT

Downstream 100 bases:

>100_bases
CAGTTGACCTCGGTCCCCGTCCGTTGGACGGCCTTAGAATTCTCGACCTGACGACCGTCGTCATGGGGCCCTACGCCTCT
TCTATCCTCGCGGACATGGG

Product: molybdopterin oxidoreductase

Products: Biotin. [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 816; Mature: 815

Protein sequence:

>816_residues
MSNNPGFSKGRRLHIGLIQPRAAILMDSFHRSTRHAGRGLAEPQMPRNPSIAAGASHASHWGSFSARWDGDRVQLTPHPE
DPAPSPILGNFADALRHQARILRPMVRRGWLDHGPGPRHRDFSNDLVPVSWETALSLVATEIARVRDSYGPEAVYGGSYG
WSSAGRFHHAQSQIHRFHNVVCGGYVRSVNSYSAGASAVILPRVMGPFEPLSRHNVTWDQICAHTDMVLAFGGMPIKNSM
IASGGITRHVEADAMARAAARGTEFWSVSPLRDDMPEAAEARWLPIRPGTDVAMMLGLAHTLLTEALYDSSFVARYCVGF
ERFASYLTGEADGLPKSADWAAEITGIGADAMRMLARRLVEGRSLITVAHSLQRAQFGEQPVWMAATLAAMVGQIGLPGG
GFNYALGAMGHTGRQINAVPIPTLPQGRNGVSTFIPVARIADMLLNPGGVFAFNGATYVYPRVRLIHWAGGNPFHHHQDL
NRLRRAFSEADTIIVQESAWTPMARFADIVLPVTMTLEREDIGAAATDPRLIAMRQVAPPIGEARDDFVIFSALAARLGL
EAAFTEGRSVREWLAHLYEQTQEALENAGLFAPSFEEFWERGEIPLPSAPDDGGLLRAFRADPQAAPLPTPSGRIEIFSE
TIAGFGYDDCPGHPTWLPSEEQPSAQTPLTLVANQPATRLHSQLDFAAHSQSHKQKGREVVRINPNDALERGIGDGDLVR
LFNARGACVASARLSADVMPGVLHLPTGAWYDPEDEAPEGPLCVHGNPNVLTRDVGTSQLAQACCGQVTVVDIARHDRPV
REVLAHRPPAFAEAAP

Sequences:

>Translated_816_residues
MSNNPGFSKGRRLHIGLIQPRAAILMDSFHRSTRHAGRGLAEPQMPRNPSIAAGASHASHWGSFSARWDGDRVQLTPHPE
DPAPSPILGNFADALRHQARILRPMVRRGWLDHGPGPRHRDFSNDLVPVSWETALSLVATEIARVRDSYGPEAVYGGSYG
WSSAGRFHHAQSQIHRFHNVVCGGYVRSVNSYSAGASAVILPRVMGPFEPLSRHNVTWDQICAHTDMVLAFGGMPIKNSM
IASGGITRHVEADAMARAAARGTEFWSVSPLRDDMPEAAEARWLPIRPGTDVAMMLGLAHTLLTEALYDSSFVARYCVGF
ERFASYLTGEADGLPKSADWAAEITGIGADAMRMLARRLVEGRSLITVAHSLQRAQFGEQPVWMAATLAAMVGQIGLPGG
GFNYALGAMGHTGRQINAVPIPTLPQGRNGVSTFIPVARIADMLLNPGGVFAFNGATYVYPRVRLIHWAGGNPFHHHQDL
NRLRRAFSEADTIIVQESAWTPMARFADIVLPVTMTLEREDIGAAATDPRLIAMRQVAPPIGEARDDFVIFSALAARLGL
EAAFTEGRSVREWLAHLYEQTQEALENAGLFAPSFEEFWERGEIPLPSAPDDGGLLRAFRADPQAAPLPTPSGRIEIFSE
TIAGFGYDDCPGHPTWLPSEEQPSAQTPLTLVANQPATRLHSQLDFAAHSQSHKQKGREVVRINPNDALERGIGDGDLVR
LFNARGACVASARLSADVMPGVLHLPTGAWYDPEDEAPEGPLCVHGNPNVLTRDVGTSQLAQACCGQVTVVDIARHDRPV
REVLAHRPPAFAEAAP
>Mature_815_residues
SNNPGFSKGRRLHIGLIQPRAAILMDSFHRSTRHAGRGLAEPQMPRNPSIAAGASHASHWGSFSARWDGDRVQLTPHPED
PAPSPILGNFADALRHQARILRPMVRRGWLDHGPGPRHRDFSNDLVPVSWETALSLVATEIARVRDSYGPEAVYGGSYGW
SSAGRFHHAQSQIHRFHNVVCGGYVRSVNSYSAGASAVILPRVMGPFEPLSRHNVTWDQICAHTDMVLAFGGMPIKNSMI
ASGGITRHVEADAMARAAARGTEFWSVSPLRDDMPEAAEARWLPIRPGTDVAMMLGLAHTLLTEALYDSSFVARYCVGFE
RFASYLTGEADGLPKSADWAAEITGIGADAMRMLARRLVEGRSLITVAHSLQRAQFGEQPVWMAATLAAMVGQIGLPGGG
FNYALGAMGHTGRQINAVPIPTLPQGRNGVSTFIPVARIADMLLNPGGVFAFNGATYVYPRVRLIHWAGGNPFHHHQDLN
RLRRAFSEADTIIVQESAWTPMARFADIVLPVTMTLEREDIGAAATDPRLIAMRQVAPPIGEARDDFVIFSALAARLGLE
AAFTEGRSVREWLAHLYEQTQEALENAGLFAPSFEEFWERGEIPLPSAPDDGGLLRAFRADPQAAPLPTPSGRIEIFSET
IAGFGYDDCPGHPTWLPSEEQPSAQTPLTLVANQPATRLHSQLDFAAHSQSHKQKGREVVRINPNDALERGIGDGDLVRL
FNARGACVASARLSADVMPGVLHLPTGAWYDPEDEAPEGPLCVHGNPNVLTRDVGTSQLAQACCGQVTVVDIARHDRPVR
EVLAHRPPAFAEAAP

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI145693196, Length=773, Percent_Identity=38.2923673997413, Blast_Score=512, Evalue=1e-146,
Organism=Escherichia coli, GI1787231, Length=791, Percent_Identity=39.5701643489254, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI87081994, Length=774, Percent_Identity=37.5968992248062, Blast_Score=501, Evalue=1e-142,
Organism=Escherichia coli, GI87081797, Length=713, Percent_Identity=30.5750350631136, Blast_Score=278, Evalue=1e-75,
Organism=Escherichia coli, GI1787870, Length=706, Percent_Identity=30.3116147308782, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI171474008, Length=723, Percent_Identity=29.1839557399723, Blast_Score=235, Evalue=8e-63,
Organism=Escherichia coli, GI3868721, Length=671, Percent_Identity=22.6527570789866, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 88563; Mature: 88432

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNPGFSKGRRLHIGLIQPRAAILMDSFHRSTRHAGRGLAEPQMPRNPSIAAGASHASH
CCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
WGSFSARWDGDRVQLTPHPEDPAPSPILGNFADALRHQARILRPMVRRGWLDHGPGPRHR
CCCCCEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DFSNDLVPVSWETALSLVATEIARVRDSYGPEAVYGGSYGWSSAGRFHHAQSQIHRFHNV
CCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHH
VCGGYVRSVNSYSAGASAVILPRVMGPFEPLSRHNVTWDQICAHTDMVLAFGGMPIKNSM
HHHHHHHHCCCCCCCCCEEEHHHHCCCCCHHHHCCCCHHHHHHHHCHHEEECCCCCCCCE
IASGGITRHVEADAMARAAARGTEFWSVSPLRDDMPEAAEARWLPIRPGTDVAMMLGLAH
ECCCCCCEEEHHHHHHHHHHCCCCCEECCCCHHCCCHHHCCCEECCCCCCHHHHHHHHHH
TLLTEALYDSSFVARYCVGFERFASYLTGEADGLPKSADWAAEITGIGADAMRMLARRLV
HHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHH
EGRSLITVAHSLQRAQFGEQPVWMAATLAAMVGQIGLPGGGFNYALGAMGHTGRQINAVP
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEC
IPTLPQGRNGVSTFIPVARIADMLLNPGGVFAFNGATYVYPRVRLIHWAGGNPFHHHQDL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCEEEEEECCCCCCHHHHHH
NRLRRAFSEADTIIVQESAWTPMARFADIVLPVTMTLEREDIGAAATDPRLIAMRQVAPP
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHEEEEEEHHHCCCCCCCCHHHHHHHHCCC
IGEARDDFVIFSALAARLGLEAAFTEGRSVREWLAHLYEQTQEALENAGLFAPSFEEFWE
CCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RGEIPLPSAPDDGGLLRAFRADPQAAPLPTPSGRIEIFSETIAGFGYDDCPGHPTWLPSE
CCCCCCCCCCCCCCEEHHCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCC
EQPSAQTPLTLVANQPATRLHSQLDFAAHSQSHKQKGREVVRINPNDALERGIGDGDLVR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCHHHH
LFNARGACVASARLSADVMPGVLHLPTGAWYDPEDEAPEGPLCVHGNPNVLTRDVGTSQL
HHCCCCCEEEHHHHCHHHCCCEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHH
AQACCGQVTVVDIARHDRPVREVLAHRPPAFAEAAP
HHHHCCCEEEEEEHHCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SNNPGFSKGRRLHIGLIQPRAAILMDSFHRSTRHAGRGLAEPQMPRNPSIAAGASHASH
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
WGSFSARWDGDRVQLTPHPEDPAPSPILGNFADALRHQARILRPMVRRGWLDHGPGPRHR
CCCCCEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DFSNDLVPVSWETALSLVATEIARVRDSYGPEAVYGGSYGWSSAGRFHHAQSQIHRFHNV
CCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHH
VCGGYVRSVNSYSAGASAVILPRVMGPFEPLSRHNVTWDQICAHTDMVLAFGGMPIKNSM
HHHHHHHHCCCCCCCCCEEEHHHHCCCCCHHHHCCCCHHHHHHHHCHHEEECCCCCCCCE
IASGGITRHVEADAMARAAARGTEFWSVSPLRDDMPEAAEARWLPIRPGTDVAMMLGLAH
ECCCCCCEEEHHHHHHHHHHCCCCCEECCCCHHCCCHHHCCCEECCCCCCHHHHHHHHHH
TLLTEALYDSSFVARYCVGFERFASYLTGEADGLPKSADWAAEITGIGADAMRMLARRLV
HHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHH
EGRSLITVAHSLQRAQFGEQPVWMAATLAAMVGQIGLPGGGFNYALGAMGHTGRQINAVP
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEC
IPTLPQGRNGVSTFIPVARIADMLLNPGGVFAFNGATYVYPRVRLIHWAGGNPFHHHQDL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCEEEEEECCCCCCHHHHHH
NRLRRAFSEADTIIVQESAWTPMARFADIVLPVTMTLEREDIGAAATDPRLIAMRQVAPP
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHEEEEEEHHHCCCCCCCCHHHHHHHHCCC
IGEARDDFVIFSALAARLGLEAAFTEGRSVREWLAHLYEQTQEALENAGLFAPSFEEFWE
CCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RGEIPLPSAPDDGGLLRAFRADPQAAPLPTPSGRIEIFSETIAGFGYDDCPGHPTWLPSE
CCCCCCCCCCCCCCEEHHCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCC
EQPSAQTPLTLVANQPATRLHSQLDFAAHSQSHKQKGREVVRINPNDALERGIGDGDLVR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCHHHH
LFNARGACVASARLSADVMPGVLHLPTGAWYDPEDEAPEGPLCVHGNPNVLTRDVGTSQL
HHCCCCCEEEHHHHCHHHCCCEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHH
AQACCGQVTVVDIARHDRPVREVLAHRPPAFAEAAP
HHHHCCCEEEEEEHHCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: Reduction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]