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The map label for this gene is aatC [H]

Identifier: 158423471

GI number: 158423471

Start: 2112395

End: 2113612

Strand: Direct

Name: aatC [H]

Synonym: AZC_1847

Alternate gene names: 158423471

Gene position: 2112395-2113612 (Clockwise)

Preceding gene: 158423470

Following gene: 158423472

Centisome position: 39.34

GC content: 65.85

Gene sequence:

>1218_bases
ATGACTGACTTTCACCGTATTCGCCGGCTGCCGCCTTATGTCTTCGAGCAGGTGAACCGTGTGAAGGCCGCCGCCCGCAA
CAACGGCGTGGACATCATCGACCTCGGCATGGGCAATCCCGATCTGGACGCGCCGGCGCACGTGATCGAGAAGCTCAAGG
AAACCATCGGCAAGCCGCGCACCGACCGTTACTCGGCCTCGAAGGGCATCCCCGGCCTGCGCCGCGCGCAGGCGGCCTAT
TACGAGCGCCGCTTCGGCGTGAAGCTCAATCCCGAGACGCAGGTGGTGGCGACGCTCGGCTCGAAGGAAGGCTTCGCCAA
CATGGCGCAGGCCATCACCGCCCCGGGCGACGTGATCCTGACCCCGAACCCGTCCTATCCCATCCACGCCTTCGGCTTCC
TCATGGCCGGCGGCGTCATCCGCTCGGTGCCGGTGGAGCCCGATGCGCAGTTCTTCCACGCCATGGAGCGGGCGGTTCAG
CACTCGATCCCGAAGCCCATCGCGGTGGTGGTGTGCTATCCGTCAAACCCCACGGCCACCGTGGCGAACCTCGATTTCTA
CAAGGACGTGGTGGCGTTCGCGAAGAAGAACGACCTCATCGTTCTCTCGGATCTCGCTTATGCCGAGCTCTATTTCGACG
ACAACGAACCGCCGCCCTCCGTGCTCCAGGTGCCGGGCGCCATGGATGTGACGGTGGAGTTCACCTCCATGTCGAAGACC
TTCTCCATGGCCGGCTGGCGTATGGGCTTTGCGGTGGGCAATGAGCGGCTCATCGCCGCGCTCGCCCGCGTGAAGTCCTA
TCTCGATTACGGCGCCTACACGCCCATCCAGGTAGCGGCCACTGCCGCGCTGAACGGCCCGCAGGAGTGCATCGCCGAGA
TGCGCGAGACCTACAAGCGCCGCCGGGATGCCATGGTGGACAGCTTCGGCCGCGCCGGCTGGACCATTCCCGTGCCTAAG
GCTTCCATGTTCGCCTGGGCGCCGATCCCGGAGCCCTTCCGGGCCATGGGCAGCGTGGAATTCTCCAAGCTGCTGATCGA
GAAGGCGGAAGTGGCGGTGGCGCCAGGCGTCGGCTTCGGCGAGCACGGCGACGAATATGTGCGCATCGCGGTCGTCGAGA
ACGAGCAGCGCATCCGCCAGGCGGCGCGCAACATCCGCCGCTTCTTCGAGCAGGCCGGCACCCTGCACAATGTGGTGCCG
CTGTCCGCCGCCCGTTGA

Upstream 100 bases:

>100_bases
TGAATGCACCGCTTTGGGTGGTTTTTGATTCACGGAAGAGTGCTAAAAGGGCCGTTCGCCGCGCCGGGAGGACAAGCGCG
CGGCCTTTGGAGCTCGTGTC

Downstream 100 bases:

>100_bases
TCCGCTGACGGAAGGGGCGTCCCACAGGGCGTCCCGTGCCAGCCTCGCGCTGGCACCGTGTCTATGATCCCGCCGCGGCC
GTGAAGGTCGCGGCTTTCTC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTDFHRIRRLPPYVFEQVNRVKAAARNNGVDIIDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAAY
YERRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPDAQFFHAMERAVQ
HSIPKPIAVVVCYPSNPTATVANLDFYKDVVAFAKKNDLIVLSDLAYAELYFDDNEPPPSVLQVPGAMDVTVEFTSMSKT
FSMAGWRMGFAVGNERLIAALARVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKRRRDAMVDSFGRAGWTIPVPK
ASMFAWAPIPEPFRAMGSVEFSKLLIEKAEVAVAPGVGFGEHGDEYVRIAVVENEQRIRQAARNIRRFFEQAGTLHNVVP
LSAAR

Sequences:

>Translated_405_residues
MTDFHRIRRLPPYVFEQVNRVKAAARNNGVDIIDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAAY
YERRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPDAQFFHAMERAVQ
HSIPKPIAVVVCYPSNPTATVANLDFYKDVVAFAKKNDLIVLSDLAYAELYFDDNEPPPSVLQVPGAMDVTVEFTSMSKT
FSMAGWRMGFAVGNERLIAALARVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKRRRDAMVDSFGRAGWTIPVPK
ASMFAWAPIPEPFRAMGSVEFSKLLIEKAEVAVAPGVGFGEHGDEYVRIAVVENEQRIRQAARNIRRFFEQAGTLHNVVP
LSAAR
>Mature_404_residues
TDFHRIRRLPPYVFEQVNRVKAAARNNGVDIIDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAAYY
ERRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPDAQFFHAMERAVQH
SIPKPIAVVVCYPSNPTATVANLDFYKDVVAFAKKNDLIVLSDLAYAELYFDDNEPPPSVLQVPGAMDVTVEFTSMSKTF
SMAGWRMGFAVGNERLIAALARVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKRRRDAMVDSFGRAGWTIPVPKA
SMFAWAPIPEPFRAMGSVEFSKLLIEKAEVAVAPGVGFGEHGDEYVRIAVVENEQRIRQAARNIRRFFEQAGTLHNVVPL
SAAR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=405, Percent_Identity=22.962962962963, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI169881279, Length=405, Percent_Identity=22.962962962963, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI56713256, Length=424, Percent_Identity=22.4056603773585, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI56713254, Length=424, Percent_Identity=22.4056603773585, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=23.0452674897119, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=52.0408163265306, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=24.5179063360882, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=23.4375, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788332, Length=217, Percent_Identity=29.9539170506912, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=24.2053789731051, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=398, Percent_Identity=23.8693467336683, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=398, Percent_Identity=23.8693467336683, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=22.2506393861893, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=24.6153846153846, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=24.6153846153846, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=24.6153846153846, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=24.6153846153846, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641770, Length=371, Percent_Identity=22.6415094339623, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641760, Length=371, Percent_Identity=22.6415094339623, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641768, Length=371, Percent_Identity=22.6415094339623, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641766, Length=371, Percent_Identity=22.6415094339623, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641764, Length=371, Percent_Identity=22.6415094339623, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45551451, Length=371, Percent_Identity=22.911051212938, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44548; Mature: 44416

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFHRIRRLPPYVFEQVNRVKAAARNNGVDIIDLGMGNPDLDAPAHVIEKLKETIGKPR
CCCHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
TDRYSASKGIPGLRRAQAAYYERRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCHHHHHHHHCCCCCEEE
TPNPSYPIHAFGFLMAGGVIRSVPVEPDAQFFHAMERAVQHSIPKPIAVVVCYPSNPTAT
CCCCCCCHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCE
VANLDFYKDVVAFAKKNDLIVLSDLAYAELYFDDNEPPPSVLQVPGAMDVTVEFTSMSKT
EECHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCHHHEECCCCEEEEEEEECCHHH
FSMAGWRMGFAVGNERLIAALARVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKR
HHHCCCEEEHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
RRDAMVDSFGRAGWTIPVPKASMFAWAPIPEPFRAMGSVEFSKLLIEKAEVAVAPGVGFG
HHHHHHHHHCCCCCEEECCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHEEEECCCCCC
EHGDEYVRIAVVENEQRIRQAARNIRRFFEQAGTLHNVVPLSAAR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
>Mature Secondary Structure 
TDFHRIRRLPPYVFEQVNRVKAAARNNGVDIIDLGMGNPDLDAPAHVIEKLKETIGKPR
CCHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
TDRYSASKGIPGLRRAQAAYYERRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCCHHHHHHHHCCCCCEEE
TPNPSYPIHAFGFLMAGGVIRSVPVEPDAQFFHAMERAVQHSIPKPIAVVVCYPSNPTAT
CCCCCCCHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCE
VANLDFYKDVVAFAKKNDLIVLSDLAYAELYFDDNEPPPSVLQVPGAMDVTVEFTSMSKT
EECHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCHHHEECCCCEEEEEEEECCHHH
FSMAGWRMGFAVGNERLIAALARVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKR
HHHCCCEEEHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
RRDAMVDSFGRAGWTIPVPKASMFAWAPIPEPFRAMGSVEFSKLLIEKAEVAVAPGVGFG
HHHHHHHHHCCCCCEEECCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHEEEECCCCCC
EHGDEYVRIAVVENEQRIRQAARNIRRFFEQAGTLHNVVPLSAAR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]