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The map label for this gene is braD [H]

Identifier: 158423383

GI number: 158423383

Start: 2010546

End: 2012357

Strand: Direct

Name: braD [H]

Synonym: AZC_1759

Alternate gene names: 158423383

Gene position: 2010546-2012357 (Clockwise)

Preceding gene: 158423382

Following gene: 158423384

Centisome position: 37.44

GC content: 69.15

Gene sequence:

>1812_bases
TTGGGAAAAGCCCTCTCCCGCTTGCGGGGGAGGGAACCTGTCCGGAGCGGGGAGGGCGCACTCTTGTCTCTCCGCTTGAC
TGACTGTCGCAGCGCCTTTCGCCGTTCGGCCAGCCCGACCCTTGAAGGTCGCAGAAGCGCCGGTGCCTTTGCCGCCCGCG
CGCCGTGGGAAACGTCCCTGATGAGCCTGATCCGCCGCCTGCTGTCCGCCGCGCTGCTGCTCGCAGCCGCGCTTCTTCTC
GCCTGGGCCGCGCCATCGGGCGTGCGCGCCCAGACCGCCGCCGGTGATCTTGCCCCGGCGCTCGCCAAGATTGCCGCCGA
CAGCTATTCCGACACCGAGGCCGCCCTCGGGATGCTGGCCACCAGCACCAATCCGCAGGCCGCCGTCATCGTCGCGGCGA
TCTCCGACAACCGCCTGCTGTTCGATCCGGCCTCCAAGGCCATCTATGTGCGCGCCAAGGATGGCAGCTTCACCGACGCG
GCCACCGGCGCCGCGGTGAGCGCCGCGCCCGCCGGCCTCAAGCCCGTGCGCCTCAACAATCGCGTGCGTCGCGCCGCCGA
CGCTGCTGCCGGCGCCCTCTCGCTGCTCAATCCCGATCCGGCCAAGCGGCTTGAGGCGGCGGCCGCTGTCTTCAAGTCGC
GCGATGCAACCGCCCTTCCGACCCTGGATGCGGCGCTCGCCAAGGAAAGCGTCGCCAATGTGCGCGCCGCGCTGGAGCAG
GCGCGCGCCGCCATCGTGCTCACCTCCGCCACCTCCGGCGAGGCCGATCGGCTCGCGGCTGTGAACCTCATCGCCGCGCG
CGGGGATCAGGAGGCGCTGGCGCTGCTCGCCAACGTGCCCGCCGATGCGCCGGCCTCCGTGAAGGCGGCGGCGGCCAACG
GCACGGCCAAGATCAATCGCTCGCTCGCCATGTGGAACGTGGCCCAGAACGTCTGGTACGGCCTCTCCCTCGGCTCCGTG
CTGCTGCTGGCGGCCATCGGTCTTGCCATCACCTTCGGCGTGATGGGCGTCATTAACATGGCCCATGGCGAGATGGTGAT
GCTCGGCGCCTACACCACCTATGTGGTGCAGGACATCATCCGCACCTCCTATCCCGGCCTCTTCGGCTGGTCGCTCGCCA
TCGCCCTGCCGCTGGCCTTCCTGTTCACGGGCCTCGTGGGCATCATCATCGAGCGCACGGTCATCCGCTTCCTCTATGGC
CGGGCCTTGGAGACCCTGCTCGCCACCTGGGGCATCTCGCTCATGCTGCAGCAGGCGGTGCGCAGCATCTTCGGCCCCAC
CAACAAGGAAGTGGGCGCGCCGTCCTGGATGTCGGGCGCCTTCGACGTGGGGCAGCTGTCCATCACCTACAACCGGCTCT
GGATCATCGTCTTCGCGCTGCTGGTCTTCTTCGCGCTGCTGGTGGTGCTCAAGCGCACCTCGCTCGGCCTCTATGTGCGC
GCGGTGACGCAGAACCGGCGCATGGCGGCGGCCATGGGCATCCGCACCGGGCGCATCGATGCGCTCACTTTCGGCCTCGG
ATCGGGCATCGCGGGCATCGCCGGCGTCGCCCTCTCGCAGATCGACAATGTGAGCCCGAACCTCGGGCAGGGCTACATCA
TCGACAGCTTCATGGTGGTGGTGTTCGGCGGCGTGGGGAACCTCTGGGGCACGCTGGTGGGCGCGCTGACGCTCGGCGTC
GCCAACAAGCTGCTGGAGCCCTTCGCGGGCGCGGTGCTCGGCAAGATCGCGCTCCTCGTCTTCATCATCCTCTTCATCCA
GAAGCGCCCGCGCGGCCTGTTCGCGCTCAAGGGCCGGGCGGTGGAAGCGTGA

Upstream 100 bases:

>100_bases
GGTGAAGTACAACTGCGGCAACTACGACACCACCAAGAACACCTGCCTCGGCGCCACCGCCGCCAAGTGAGCAGCAATGT
GAGCTGAGGCGGCTCGGTCC

Downstream 100 bases:

>100_bases
ACATCATGCGCGGCTCAGGCATTCTCGATCGCCGCGGGGCGATCTTCATCATCCTCGTGCTGGCGGCGGGCGTGCTGGTG
CCGGCCGGCAATCTGCTGGC

Product: ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MGKALSRLRGREPVRSGEGALLSLRLTDCRSAFRRSASPTLEGRRSAGAFAARAPWETSLMSLIRRLLSAALLLAAALLL
AWAAPSGVRAQTAAGDLAPALAKIAADSYSDTEAALGMLATSTNPQAAVIVAAISDNRLLFDPASKAIYVRAKDGSFTDA
ATGAAVSAAPAGLKPVRLNNRVRRAADAAAGALSLLNPDPAKRLEAAAAVFKSRDATALPTLDAALAKESVANVRAALEQ
ARAAIVLTSATSGEADRLAAVNLIAARGDQEALALLANVPADAPASVKAAAANGTAKINRSLAMWNVAQNVWYGLSLGSV
LLLAAIGLAITFGVMGVINMAHGEMVMLGAYTTYVVQDIIRTSYPGLFGWSLAIALPLAFLFTGLVGIIIERTVIRFLYG
RALETLLATWGISLMLQQAVRSIFGPTNKEVGAPSWMSGAFDVGQLSITYNRLWIIVFALLVFFALLVVLKRTSLGLYVR
AVTQNRRMAAAMGIRTGRIDALTFGLGSGIAGIAGVALSQIDNVSPNLGQGYIIDSFMVVVFGGVGNLWGTLVGALTLGV
ANKLLEPFAGAVLGKIALLVFIILFIQKRPRGLFALKGRAVEA

Sequences:

>Translated_603_residues
MGKALSRLRGREPVRSGEGALLSLRLTDCRSAFRRSASPTLEGRRSAGAFAARAPWETSLMSLIRRLLSAALLLAAALLL
AWAAPSGVRAQTAAGDLAPALAKIAADSYSDTEAALGMLATSTNPQAAVIVAAISDNRLLFDPASKAIYVRAKDGSFTDA
ATGAAVSAAPAGLKPVRLNNRVRRAADAAAGALSLLNPDPAKRLEAAAAVFKSRDATALPTLDAALAKESVANVRAALEQ
ARAAIVLTSATSGEADRLAAVNLIAARGDQEALALLANVPADAPASVKAAAANGTAKINRSLAMWNVAQNVWYGLSLGSV
LLLAAIGLAITFGVMGVINMAHGEMVMLGAYTTYVVQDIIRTSYPGLFGWSLAIALPLAFLFTGLVGIIIERTVIRFLYG
RALETLLATWGISLMLQQAVRSIFGPTNKEVGAPSWMSGAFDVGQLSITYNRLWIIVFALLVFFALLVVLKRTSLGLYVR
AVTQNRRMAAAMGIRTGRIDALTFGLGSGIAGIAGVALSQIDNVSPNLGQGYIIDSFMVVVFGGVGNLWGTLVGALTLGV
ANKLLEPFAGAVLGKIALLVFIILFIQKRPRGLFALKGRAVEA
>Mature_602_residues
GKALSRLRGREPVRSGEGALLSLRLTDCRSAFRRSASPTLEGRRSAGAFAARAPWETSLMSLIRRLLSAALLLAAALLLA
WAAPSGVRAQTAAGDLAPALAKIAADSYSDTEAALGMLATSTNPQAAVIVAAISDNRLLFDPASKAIYVRAKDGSFTDAA
TGAAVSAAPAGLKPVRLNNRVRRAADAAAGALSLLNPDPAKRLEAAAAVFKSRDATALPTLDAALAKESVANVRAALEQA
RAAIVLTSATSGEADRLAAVNLIAARGDQEALALLANVPADAPASVKAAAANGTAKINRSLAMWNVAQNVWYGLSLGSVL
LLAAIGLAITFGVMGVINMAHGEMVMLGAYTTYVVQDIIRTSYPGLFGWSLAIALPLAFLFTGLVGIIIERTVIRFLYGR
ALETLLATWGISLMLQQAVRSIFGPTNKEVGAPSWMSGAFDVGQLSITYNRLWIIVFALLVFFALLVVLKRTSLGLYVRA
VTQNRRMAAAMGIRTGRIDALTFGLGSGIAGIAGVALSQIDNVSPNLGQGYIIDSFMVVVFGGVGNLWGTLVGALTLGVA
NKLLEPFAGAVLGKIALLVFIILFIQKRPRGLFALKGRAVEA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=304, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 62845; Mature: 62714

Theoretical pI: Translated: 11.00; Mature: 11.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKALSRLRGREPVRSGEGALLSLRLTDCRSAFRRSASPTLEGRRSAGAFAARAPWETSL
CCHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
MSLIRRLLSAALLLAAALLLAWAAPSGVRAQTAAGDLAPALAKIAADSYSDTEAALGMLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHC
TSTNPQAAVIVAAISDNRLLFDPASKAIYVRAKDGSFTDAATGAAVSAAPAGLKPVRLNN
CCCCCCEEEEEEEECCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHH
RVRRAADAAAGALSLLNPDPAKRLEAAAAVFKSRDATALPTLDAALAKESVANVRAALEQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ARAAIVLTSATSGEADRLAAVNLIAARGDQEALALLANVPADAPASVKAAAANGTAKINR
CCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEECCCCCHHHHH
SLAMWNVAQNVWYGLSLGSVLLLAAIGLAITFGVMGVINMAHGEMVMLGAYTTYVVQDII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
RTSYPGLFGWSLAIALPLAFLFTGLVGIIIERTVIRFLYGRALETLLATWGISLMLQQAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSIFGPTNKEVGAPSWMSGAFDVGQLSITYNRLWIIVFALLVFFALLVVLKRTSLGLYVR
HHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AVTQNRRMAAAMGIRTGRIDALTFGLGSGIAGIAGVALSQIDNVSPNLGQGYIIDSFMVV
EECCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VFGGVGNLWGTLVGALTLGVANKLLEPFAGAVLGKIALLVFIILFIQKRPRGLFALKGRA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
VEA
CCC
>Mature Secondary Structure 
GKALSRLRGREPVRSGEGALLSLRLTDCRSAFRRSASPTLEGRRSAGAFAARAPWETSL
CHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
MSLIRRLLSAALLLAAALLLAWAAPSGVRAQTAAGDLAPALAKIAADSYSDTEAALGMLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHC
TSTNPQAAVIVAAISDNRLLFDPASKAIYVRAKDGSFTDAATGAAVSAAPAGLKPVRLNN
CCCCCCEEEEEEEECCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEHHH
RVRRAADAAAGALSLLNPDPAKRLEAAAAVFKSRDATALPTLDAALAKESVANVRAALEQ
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ARAAIVLTSATSGEADRLAAVNLIAARGDQEALALLANVPADAPASVKAAAANGTAKINR
CCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEECCCCCHHHHH
SLAMWNVAQNVWYGLSLGSVLLLAAIGLAITFGVMGVINMAHGEMVMLGAYTTYVVQDII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
RTSYPGLFGWSLAIALPLAFLFTGLVGIIIERTVIRFLYGRALETLLATWGISLMLQQAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSIFGPTNKEVGAPSWMSGAFDVGQLSITYNRLWIIVFALLVFFALLVVLKRTSLGLYVR
HHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AVTQNRRMAAAMGIRTGRIDALTFGLGSGIAGIAGVALSQIDNVSPNLGQGYIIDSFMVV
EECCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VFGGVGNLWGTLVGALTLGVANKLLEPFAGAVLGKIALLVFIILFIQKRPRGLFALKGRA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
VEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]