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The map label for this gene is dacC [H]

Identifier: 158423216

GI number: 158423216

Start: 1816390

End: 1818279

Strand: Reverse

Name: dacC [H]

Synonym: AZC_1592

Alternate gene names: 158423216

Gene position: 1818279-1816390 (Counterclockwise)

Preceding gene: 158423220

Following gene: 158423213

Centisome position: 33.86

GC content: 69.21

Gene sequence:

>1890_bases
GTGCACTGCACAATATGGCATGCAATGTCGGGTTTACGCCTTGGTAACCGCACGTTCTTAGGCTGCATCCAGAGTTCATT
CCTGCGGTACGGGCTCGCTGGCTCCCGCGACACATCCAGCTTGAGCTTTACCGCAATGCACCACCAGCCGGGTCCTCCGC
CCCGGCCGGGCAGATGGAACAGTTTCATGACCCTTGCGCTCGGCCCCTCTCTCACCCGAAAGTGGCTTGCGGCCGCCCTC
GTGGCGGCCCTTGCGGTGACGGCAACAGCAGCCGAGGCGAAGCCGAAGAAGTCGCGGAGCGCCGCGCAGTCCTCGTCCTC
CCGCTCCTCGGGCGGCGATGAATATGCCGGCTGGAAGCGCGGCACGGCGGCCATCGTGGTGGATGGCAACACGGGCAAGG
TGCTTTACGAGGAGAATGCCGACTCCCTGCGGCATCCTGCCTCCCTCACCAAGATCATGACCCTCTACATGCTGTTCGAG
CAGCTTCAGGCCGGCCGGCTCAAGCTCGACAGCGACCTGCCCGTCTCCGCCCATGCGGCGTCCCAGTCGCCCACCAAGCT
CAACCTGCGTCCGGGCTCCACCATCGAGGTGGAGGACGCCATCAAGGCGGTCGTCACCCGCTCGGCCAATGACGCGGCCG
TGGTCATCGGCGAAGCCATCGGCGGCACGGAATCCAACTTCGCCGAGATGATGACGCGCAAGGCGCGCGCGCTCGGCATG
AGCAACACCACCTTCCGCAATGCCTCCGGCCTGCCCAACCCCGGCCAGGTCACCACCGCGCGCGACCTCTCCGTCCTCGG
CCGGGCGATCCAGGACCGCTTCCCGCGGGAGTATCGCTACTTCTCCACCCGCGCCTTCGTGTATCGCGGCGAGACCATCG
GCAACCACAACCGCCTGATGCTCCGCATGGAAGGCGTGGACGGCATCAAGACCGGCTACACCAACGCGTCCGGCTTCAAT
CTGGTGACCTCGCTGCACCGCGACGACCGCTTCCTCGTGGGCGTGGTGCTCGGCGGCTCCAGCGCCAGCTCGCGCGACCA
GCGCATGGCCAGCATCCTCACCTCCAACCTGCCGCGCGCCTATGCGGGAGGCCGCGTTGCGCCGAAGGTCATCGAGACCG
CCCAGCGCGACGACGAGCCGGCGCCGCGCCCCATGCCCATTCCGGTCGCGGCCCGCCAGAGCGAGCCCGCGCAGGCCGTG
GCCCCGCTGCCGCCGCCGCAGCGCGTCGCCTATGCCGCCGCCGATCCGGTGACCACCGCCAGTGTCGCGCCGGTGCGCGC
CCCGACGCCGGGATCCGCCGAGCCCATCAAGCCGGTGGCTGTGCGGACCACGACCATCGCCCGTCCCGGCAGCAACCAGA
TGCCGGCGCCCACCTTCAGCGGCCAGCCCTCCGGAACGCTGGGCTATCTGCCCGCCCAGTCCGCCGCCGCCGCCCAGTCC
GACATGGAATCTCCTCCCGGCGACCTGCTGATGGGCCCTCCCCCCGAGCGTGAGACCTCGCCGGTCGCCCATGGTGTGCG
CACCGCCTCGGCCGCTCCCGTCGCCCTTCCGGCCGCTACGGTGGCGAGCGCCACCACGCCCGCTCCCAAGCCTGTCCGCG
TCGCCTCCACGGGACCTGTCGCGACGCCGCGCAGCGCGCCGCCCCGCTCGGGCTGGATCATCCAGATCGGCGCCTTCGGC
GGCGAGAAGGAAGCCCGCTCCCAGCTCGACGCCGCCCGCGGCAAGGCCGGCAAGCTGCTCAAGAGCGCCGATCCCTACAC
GGAGAAGGTGGAGAAGGGCCGCAGCGACATTTACCGCGCCCGCTTTGCCGGTCTCACGGAAAAGGATGCGAAAGAGGCCT
GCCGTTTACTCGAGCGCAACAAATTCGACTGCATGACTCTTCGGAACTGA

Upstream 100 bases:

>100_bases
CTCCATCCATTTTTGCCGACTGACGCATGAGCGGGTGTCGTCGGCGCTACCTCCCGCAGCCCAAATATCGTGCAACGCAC
CATAACCGTCAAGCATTTTT

Downstream 100 bases:

>100_bases
TGTGAGGGAGTCCTCAGCGATGTCGGCGCAGGATCACGTCCTTGGCCTGGTTGACCCGCGAAGCCAGATAGTCCGAGCCC
CCCTGGTCGGGATGGAGTTT

Product: D-alanyl-D-alanine carboxypeptidase precursor

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MHCTIWHAMSGLRLGNRTFLGCIQSSFLRYGLAGSRDTSSLSFTAMHHQPGPPPRPGRWNSFMTLALGPSLTRKWLAAAL
VAALAVTATAAEAKPKKSRSAAQSSSSRSSGGDEYAGWKRGTAAIVVDGNTGKVLYEENADSLRHPASLTKIMTLYMLFE
QLQAGRLKLDSDLPVSAHAASQSPTKLNLRPGSTIEVEDAIKAVVTRSANDAAVVIGEAIGGTESNFAEMMTRKARALGM
SNTTFRNASGLPNPGQVTTARDLSVLGRAIQDRFPREYRYFSTRAFVYRGETIGNHNRLMLRMEGVDGIKTGYTNASGFN
LVTSLHRDDRFLVGVVLGGSSASSRDQRMASILTSNLPRAYAGGRVAPKVIETAQRDDEPAPRPMPIPVAARQSEPAQAV
APLPPPQRVAYAAADPVTTASVAPVRAPTPGSAEPIKPVAVRTTTIARPGSNQMPAPTFSGQPSGTLGYLPAQSAAAAQS
DMESPPGDLLMGPPPERETSPVAHGVRTASAAPVALPAATVASATTPAPKPVRVASTGPVATPRSAPPRSGWIIQIGAFG
GEKEARSQLDAARGKAGKLLKSADPYTEKVEKGRSDIYRARFAGLTEKDAKEACRLLERNKFDCMTLRN

Sequences:

>Translated_629_residues
MHCTIWHAMSGLRLGNRTFLGCIQSSFLRYGLAGSRDTSSLSFTAMHHQPGPPPRPGRWNSFMTLALGPSLTRKWLAAAL
VAALAVTATAAEAKPKKSRSAAQSSSSRSSGGDEYAGWKRGTAAIVVDGNTGKVLYEENADSLRHPASLTKIMTLYMLFE
QLQAGRLKLDSDLPVSAHAASQSPTKLNLRPGSTIEVEDAIKAVVTRSANDAAVVIGEAIGGTESNFAEMMTRKARALGM
SNTTFRNASGLPNPGQVTTARDLSVLGRAIQDRFPREYRYFSTRAFVYRGETIGNHNRLMLRMEGVDGIKTGYTNASGFN
LVTSLHRDDRFLVGVVLGGSSASSRDQRMASILTSNLPRAYAGGRVAPKVIETAQRDDEPAPRPMPIPVAARQSEPAQAV
APLPPPQRVAYAAADPVTTASVAPVRAPTPGSAEPIKPVAVRTTTIARPGSNQMPAPTFSGQPSGTLGYLPAQSAAAAQS
DMESPPGDLLMGPPPERETSPVAHGVRTASAAPVALPAATVASATTPAPKPVRVASTGPVATPRSAPPRSGWIIQIGAFG
GEKEARSQLDAARGKAGKLLKSADPYTEKVEKGRSDIYRARFAGLTEKDAKEACRLLERNKFDCMTLRN
>Mature_629_residues
MHCTIWHAMSGLRLGNRTFLGCIQSSFLRYGLAGSRDTSSLSFTAMHHQPGPPPRPGRWNSFMTLALGPSLTRKWLAAAL
VAALAVTATAAEAKPKKSRSAAQSSSSRSSGGDEYAGWKRGTAAIVVDGNTGKVLYEENADSLRHPASLTKIMTLYMLFE
QLQAGRLKLDSDLPVSAHAASQSPTKLNLRPGSTIEVEDAIKAVVTRSANDAAVVIGEAIGGTESNFAEMMTRKARALGM
SNTTFRNASGLPNPGQVTTARDLSVLGRAIQDRFPREYRYFSTRAFVYRGETIGNHNRLMLRMEGVDGIKTGYTNASGFN
LVTSLHRDDRFLVGVVLGGSSASSRDQRMASILTSNLPRAYAGGRVAPKVIETAQRDDEPAPRPMPIPVAARQSEPAQAV
APLPPPQRVAYAAADPVTTASVAPVRAPTPGSAEPIKPVAVRTTTIARPGSNQMPAPTFSGQPSGTLGYLPAQSAAAAQS
DMESPPGDLLMGPPPERETSPVAHGVRTASAAPVALPAATVASATTPAPKPVRVASTGPVATPRSAPPRSGWIIQIGAFG
GEKEARSQLDAARGKAGKLLKSADPYTEKVEKGRSDIYRARFAGLTEKDAKEACRLLERNKFDCMTLRN

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=239, Percent_Identity=37.6569037656904, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1786851, Length=237, Percent_Identity=34.1772151898734, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI87082022, Length=236, Percent_Identity=34.7457627118644, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87082054, Length=211, Percent_Identity=33.6492890995261, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 66581; Mature: 66581

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCTIWHAMSGLRLGNRTFLGCIQSSFLRYGLAGSRDTSSLSFTAMHHQPGPPPRPGRWN
CEEEHEEHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
SFMTLALGPSLTRKWLAAALVAALAVTATAAEAKPKKSRSAAQSSSSRSSGGDEYAGWKR
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCC
GTAAIVVDGNTGKVLYEENADSLRHPASLTKIMTLYMLFEQLQAGRLKLDSDLPVSAHAA
CCEEEEEECCCCEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SQSPTKLNLRPGSTIEVEDAIKAVVTRSANDAAVVIGEAIGGTESNFAEMMTRKARALGM
CCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
SNTTFRNASGLPNPGQVTTARDLSVLGRAIQDRFPREYRYFSTRAFVYRGETIGNHNRLM
CCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCHHHHEEEEEEEEEECCEECCCCEEE
LRMEGVDGIKTGYTNASGFNLVTSLHRDDRFLVGVVLGGSSASSRDQRMASILTSNLPRA
EEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCH
YAGGRVAPKVIETAQRDDEPAPRPMPIPVAARQSEPAQAVAPLPPPQRVAYAAADPVTTA
HCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCC
SVAPVRAPTPGSAEPIKPVAVRTTTIARPGSNQMPAPTFSGQPSGTLGYLPAQSAAAAQS
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
DMESPPGDLLMGPPPERETSPVAHGVRTASAAPVALPAATVASATTPAPKPVRVASTGPV
HCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCC
ATPRSAPPRSGWIIQIGAFGGEKEARSQLDAARGKAGKLLKSADPYTEKVEKGRSDIYRA
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHH
RFAGLTEKDAKEACRLLERNKFDCMTLRN
HHCCCCHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MHCTIWHAMSGLRLGNRTFLGCIQSSFLRYGLAGSRDTSSLSFTAMHHQPGPPPRPGRWN
CEEEHEEHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
SFMTLALGPSLTRKWLAAALVAALAVTATAAEAKPKKSRSAAQSSSSRSSGGDEYAGWKR
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCC
GTAAIVVDGNTGKVLYEENADSLRHPASLTKIMTLYMLFEQLQAGRLKLDSDLPVSAHAA
CCEEEEEECCCCEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SQSPTKLNLRPGSTIEVEDAIKAVVTRSANDAAVVIGEAIGGTESNFAEMMTRKARALGM
CCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCC
SNTTFRNASGLPNPGQVTTARDLSVLGRAIQDRFPREYRYFSTRAFVYRGETIGNHNRLM
CCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCHHHHEEEEEEEEEECCEECCCCEEE
LRMEGVDGIKTGYTNASGFNLVTSLHRDDRFLVGVVLGGSSASSRDQRMASILTSNLPRA
EEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCH
YAGGRVAPKVIETAQRDDEPAPRPMPIPVAARQSEPAQAVAPLPPPQRVAYAAADPVTTA
HCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCC
SVAPVRAPTPGSAEPIKPVAVRTTTIARPGSNQMPAPTFSGQPSGTLGYLPAQSAAAAQS
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
DMESPPGDLLMGPPPERETSPVAHGVRTASAAPVALPAATVASATTPAPKPVRVASTGPV
HCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCC
ATPRSAPPRSGWIIQIGAFGGEKEARSQLDAARGKAGKLLKSADPYTEKVEKGRSDIYRA
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHH
RFAGLTEKDAKEACRLLERNKFDCMTLRN
HHCCCCHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]