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The map label for this gene is pcaB [H]

Identifier: 158423065

GI number: 158423065

Start: 1641997

End: 1643061

Strand: Reverse

Name: pcaB [H]

Synonym: AZC_1441

Alternate gene names: 158423065

Gene position: 1643061-1641997 (Counterclockwise)

Preceding gene: 158423066

Following gene: 158423064

Centisome position: 30.6

GC content: 71.08

Gene sequence:

>1065_bases
ATGAGCCTTTCGCCGTTCGATAACGCCCTCCTCCGCGACTTCCTCGGCGATGCCGAGGTGGAAGCGGCGCTGTGCGCGGA
GGCGGACATCAGGGCCATGCTCGCCTTCGAGGCAGCGCTTGCGCGGGCGGAGGCAATCCATGGCCTCATCCCCGCCGAGG
CGGCCGAGACCATCGCCACCGTTTGTGTGCAGTTCCAGCCGGATGTGGCGGCGCTGGCACGGGGTGTGGCCAGCGATGGC
GTGGTGGTGCCGGCGCTGGTGCGCGCGTTGCGCGCGGCGGTCGGCCCGGAGGCCGCCCCCCATGTCCATCGCGGCGCCAC
CAGCCAGGACGTGATCGATACCAGCCTGATGCTGCGGCTGAAGCCGCTGGCGGCGCGCTTTTGCACCCGCCTCGGCGCCA
TCCTTGCCCGACTCGCGGCGCTGGACGCCGCCTTCGGAGAACGGGCCTTGATGGGCCACACCCGCATGCAGGCGGCCCTG
CCGATCACGGTATCGGACCGCCTGCGCAGTTGGTCCGGGCCGCTGGCGCCGCTCATGCTGCGGCTCGACCGGCTGTCCTT
TCCGGTGCAGTTCGGCGGCGCCGTCGGCACGCTGGAGGGGCTGGAGGGCAAGGGCGCGCAGGTACGGGCGGCGCTGGCCG
CTGAACTCGACCTTGAGGATACGCCGCAGTGGCATAGCACGCGCACCGTGATCACCGATCTCGGCCATCTGCTCGCGCTC
ATCACCGGCGGCCTCGGCAAGATGGGGCAGGACATCGCCCTCATGGCGCAGGCGGGCGATGACATCACGCTGAGCGGCGG
CGGCGGCTCCTCCGCCATGCCGCACAAGCAGAACCCCGTGGCGGCAGAGACGCTGGTGGCTCTCGCCCGCTTCAATGCGG
TGCAGGCTTCCGCCCTCCAGCAGGCCATGGTTCACGAGCAGGAGCGCTCCGGCGCCGCCTGGACGCTGGAATGGCTCACC
CTGCCGCATATGCTGGCCGCCACCGGCGCCGCTTTGCGACATGCGGAGGCGCTGACCCTTTCGATCCTCCGCCTCGGCGG
AGCCGACGACACCCGACCCGGTTGA

Upstream 100 bases:

>100_bases
GGAAACGGTCTTTCTCGATATATGAGGAGAAACGGGCGGCCCCGCCGCCCGCCTCGGCCAGCGCCGCGCCACTGAGCGTG
GTGGACAGATCAGGGACGAC

Downstream 100 bases:

>100_bases
CCCTCAGGGCAGCCCGCGAACAACAACAGCCGGACTGTCCGCACGCGGGGCCCCGCCCAAGCGGACGCAGGAGGACGCAA
TGAGGACGCGCATCATCGCC

Product: 3-carboxy-cis,cis-muconate cycloisomerase

Products: NA

Alternate protein names: 3-carboxymuconate lactonizing enzyme; CMLE [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSLSPFDNALLRDFLGDAEVEAALCAEADIRAMLAFEAALARAEAIHGLIPAEAAETIATVCVQFQPDVAALARGVASDG
VVVPALVRALRAAVGPEAAPHVHRGATSQDVIDTSLMLRLKPLAARFCTRLGAILARLAALDAAFGERALMGHTRMQAAL
PITVSDRLRSWSGPLAPLMLRLDRLSFPVQFGGAVGTLEGLEGKGAQVRAALAAELDLEDTPQWHSTRTVITDLGHLLAL
ITGGLGKMGQDIALMAQAGDDITLSGGGGSSAMPHKQNPVAAETLVALARFNAVQASALQQAMVHEQERSGAAWTLEWLT
LPHMLAATGAALRHAEALTLSILRLGGADDTRPG

Sequences:

>Translated_354_residues
MSLSPFDNALLRDFLGDAEVEAALCAEADIRAMLAFEAALARAEAIHGLIPAEAAETIATVCVQFQPDVAALARGVASDG
VVVPALVRALRAAVGPEAAPHVHRGATSQDVIDTSLMLRLKPLAARFCTRLGAILARLAALDAAFGERALMGHTRMQAAL
PITVSDRLRSWSGPLAPLMLRLDRLSFPVQFGGAVGTLEGLEGKGAQVRAALAAELDLEDTPQWHSTRTVITDLGHLLAL
ITGGLGKMGQDIALMAQAGDDITLSGGGGSSAMPHKQNPVAAETLVALARFNAVQASALQQAMVHEQERSGAAWTLEWLT
LPHMLAATGAALRHAEALTLSILRLGGADDTRPG
>Mature_353_residues
SLSPFDNALLRDFLGDAEVEAALCAEADIRAMLAFEAALARAEAIHGLIPAEAAETIATVCVQFQPDVAALARGVASDGV
VVPALVRALRAAVGPEAAPHVHRGATSQDVIDTSLMLRLKPLAARFCTRLGAILARLAALDAAFGERALMGHTRMQAALP
ITVSDRLRSWSGPLAPLMLRLDRLSFPVQFGGAVGTLEGLEGKGAQVRAALAAELDLEDTPQWHSTRTVITDLGHLLALI
TGGLGKMGQDIALMAQAGDDITLSGGGGSSAMPHKQNPVAAETLVALARFNAVQASALQQAMVHEQERSGAAWTLEWLTL
PHMLAATGAALRHAEALTLSILRLGGADDTRPG

Specific function: Catalyzes an anti cycloisomerization [H]

COG id: COG0015

COG function: function code F; Adenylosuccinate lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family [H]

Homologues:

Organism=Drosophila melanogaster, GI24647570, Length=211, Percent_Identity=30.3317535545024, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019468
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761
- InterPro:   IPR012789 [H]

Pfam domain/function: PF10397 ADSL_C; PF00206 Lyase_1 [H]

EC number: =5.5.1.2 [H]

Molecular weight: Translated: 36902; Mature: 36771

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSPFDNALLRDFLGDAEVEAALCAEADIRAMLAFEAALARAEAIHGLIPAEAAETIAT
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VCVQFQPDVAALARGVASDGVVVPALVRALRAAVGPEAAPHVHRGATSQDVIDTSLMLRL
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHH
KPLAARFCTRLGAILARLAALDAAFGERALMGHTRMQAALPITVSDRLRSWSGPLAPLML
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHH
RLDRLSFPVQFGGAVGTLEGLEGKGAQVRAALAAELDLEDTPQWHSTRTVITDLGHLLAL
HHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ITGGLGKMGQDIALMAQAGDDITLSGGGGSSAMPHKQNPVAAETLVALARFNAVQASALQ
HHCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAMVHEQERSGAAWTLEWLTLPHMLAATGAALRHAEALTLSILRLGGADDTRPG
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLSPFDNALLRDFLGDAEVEAALCAEADIRAMLAFEAALARAEAIHGLIPAEAAETIAT
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VCVQFQPDVAALARGVASDGVVVPALVRALRAAVGPEAAPHVHRGATSQDVIDTSLMLRL
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHH
KPLAARFCTRLGAILARLAALDAAFGERALMGHTRMQAALPITVSDRLRSWSGPLAPLML
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHH
RLDRLSFPVQFGGAVGTLEGLEGKGAQVRAALAAELDLEDTPQWHSTRTVITDLGHLLAL
HHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ITGGLGKMGQDIALMAQAGDDITLSGGGGSSAMPHKQNPVAAETLVALARFNAVQASALQ
HHCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAMVHEQERSGAAWTLEWLTLPHMLAATGAALRHAEALTLSILRLGGADDTRPG
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101 [H]