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The map label for this gene is iorA [H]

Identifier: 158423018

GI number: 158423018

Start: 1577938

End: 1578390

Strand: Reverse

Name: iorA [H]

Synonym: AZC_1394

Alternate gene names: 158423018

Gene position: 1578390-1577938 (Counterclockwise)

Preceding gene: 158423020

Following gene: 158423017

Centisome position: 29.39

GC content: 67.99

Gene sequence:

>453_bases
ATGAGCGCCATCTCCATCAACGGCAAGACCTACCAGATCGCATCAGACCCAGACACGCCGCTGCTGTGGGTGCTGCGGGA
CGAACTGGGGCTGACCGGCACCAAGTTCGGCTGCGGCGTCGCGCAATGCGGCGCCTGCACCGTGCATGTGGACGGGGTCG
CGGTGCGCTCCTGCCAGATGCCGGTCGGCACGGTCGGCACGCGCGCCGTGACCACCATCGAAGCCGTCGGCGACACGCCT
GCGGGCGCCAAGATCCAGAAGGCCTGGCTCGATCTCGAGGTGGTCCAGTGCGGCTATTGCCAGCCCGGCCAGATCATGTC
GGCGACCGCTCTGCTGGCCGCCAATCCGAAGCCGGACGACGCGGCCATCGACGCCGCCATGGCCGGGAATCTGTGCCGCT
GCGGGACCTATGTCCGCATTCGCGAAGGGATCAAGCATGCCGCGCAGTCCTGA

Upstream 100 bases:

>100_bases
GACGCCCCGCGCCCGTCTGAAATCGCCTTCTATTTGTCCTGCCCGCTCCTCCCGGGCCCGCCTAGGTTGCGGGTTCAATT
TCCGCCCCGGGGCCCTGCAC

Downstream 100 bases:

>100_bases
GATGCAGCCCGACAGCCCCACCCTCTCGCGCCGCTCGCTTCTGCGCGGCGCCGCGGCCGTCCTGGGCGGCCTTGTGATCG
GCATCGAACTGCCGGCACGG

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSAISINGKTYQIASDPDTPLLWVLRDELGLTGTKFGCGVAQCGACTVHVDGVAVRSCQMPVGTVGTRAVTTIEAVGDTP
AGAKIQKAWLDLEVVQCGYCQPGQIMSATALLAANPKPDDAAIDAAMAGNLCRCGTYVRIREGIKHAAQS

Sequences:

>Translated_150_residues
MSAISINGKTYQIASDPDTPLLWVLRDELGLTGTKFGCGVAQCGACTVHVDGVAVRSCQMPVGTVGTRAVTTIEAVGDTP
AGAKIQKAWLDLEVVQCGYCQPGQIMSATALLAANPKPDDAAIDAAMAGNLCRCGTYVRIREGIKHAAQS
>Mature_149_residues
SAISINGKTYQIASDPDTPLLWVLRDELGLTGTKFGCGVAQCGACTVHVDGVAVRSCQMPVGTVGTRAVTTIEAVGDTPA
GAKIQKAWLDLEVVQCGYCQPGQIMSATALLAANPKPDDAAIDAAMAGNLCRCGTYVRIREGIKHAAQS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=38.125, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI71773480, Length=156, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786480, Length=160, Percent_Identity=37.5, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=40.4255319148936, Blast_Score=96, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=39.2156862745098, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=151, Percent_Identity=39.7350993377483, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=38.8157894736842, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737937, Length=156, Percent_Identity=39.7435897435897, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=34.6153846153846, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647197, Length=159, Percent_Identity=33.9622641509434, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=33.75, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=33.125, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=32.0512820512821, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15537; Mature: 15406

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAISINGKTYQIASDPDTPLLWVLRDELGLTGTKFGCGVAQCGACTVHVDGVAVRSCQM
CCEEECCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHCCEEEEEECCEEEEECCC
PVGTVGTRAVTTIEAVGDTPAGAKIQKAWLDLEVVQCGYCQPGQIMSATALLAANPKPDD
CCCCCCCCCEEEEEECCCCCCCCEEEHHHEEEEEEEECCCCCCCEEEEEEEEECCCCCCH
AAIDAAMAGNLCRCGTYVRIREGIKHAAQS
HHHHHHHHCCCHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAISINGKTYQIASDPDTPLLWVLRDELGLTGTKFGCGVAQCGACTVHVDGVAVRSCQM
CEEECCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHCCEEEEEECCEEEEECCC
PVGTVGTRAVTTIEAVGDTPAGAKIQKAWLDLEVVQCGYCQPGQIMSATALLAANPKPDD
CCCCCCCCCEEEEEECCCCCCCCEEEHHHEEEEEEEECCCCCCCEEEEEEEEECCCCCCH
AAIDAAMAGNLCRCGTYVRIREGIKHAAQS
HHHHHHHHCCCHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]