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The map label for this gene is rnpA

Identifier: 15834787

GI number: 15834787

Start: 200199

End: 200558

Strand: Reverse

Name: rnpA

Synonym: TC0167

Alternate gene names: 15834787

Gene position: 200558-200199 (Counterclockwise)

Preceding gene: 15834788

Following gene: 15834785

Centisome position: 18.69

GC content: 43.61

Gene sequence:

>360_bases
GTGCATCGGTTAACTCTACCTAAAAGTGCCCGCCTATTGAAACGTAAACAATTTGTTTACGTGCAGCGTTGTGGGCAATA
TTGTCGTACTGATCAGGCAACTTTACGAATAGTTCCTTCTCGTCATTCGAACATCCGTAAAGTAGGGGTTACTGTTTCTA
AAAAATTTGGGAAAGCCCATCAGCGCAATCGCTTTAAAAGAATTGTGCGAGAGGCTTTTAGGCATGTGCGACCAAATCTT
CCCGCATGTCAAGTGGTAGTGTCTCCTAAAGGGGGCACTCTACCAAATTTTGGTAAACTATCCGCGGATCTTCTTAAGCA
TATTCCAGAGGCTTTGCCTCTCGTTACTTCTTCTAAGTAG

Upstream 100 bases:

>100_bases
ATTTAGAGCTCGCATGGCTACAAAAAGTGGAAGAAATCTTTTAAATCGTCGTCGCCGTCACGGCAGACATTCCTTAATTG
ATCTCTAAGATCTTTCATTT

Downstream 100 bases:

>100_bases
TTTTTTATTTTGGTCAAAAAATAAAAAACCATTCCACGCTATAGAGGCATGGAATGGGAAGGAATACTAGTTTTGTAACC
TTTAAGACTGATGTCGCATA

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MHRLTLPKSARLLKRKQFVYVQRCGQYCRTDQATLRIVPSRHSNIRKVGVTVSKKFGKAHQRNRFKRIVREAFRHVRPNL
PACQVVVSPKGGTLPNFGKLSADLLKHIPEALPLVTSSK

Sequences:

>Translated_119_residues
MHRLTLPKSARLLKRKQFVYVQRCGQYCRTDQATLRIVPSRHSNIRKVGVTVSKKFGKAHQRNRFKRIVREAFRHVRPNL
PACQVVVSPKGGTLPNFGKLSADLLKHIPEALPLVTSSK
>Mature_119_residues
MHRLTLPKSARLLKRKQFVYVQRCGQYCRTDQATLRIVPSRHSNIRKVGVTVSKKFGKAHQRNRFKRIVREAFRHVRPNL
PACQVVVSPKGGTLPNFGKLSADLLKHIPEALPLVTSSK

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_CHLMU (Q9PLD7)

Other databases:

- EMBL:   AE002160
- RefSeq:   NP_296546.1
- ProteinModelPortal:   Q9PLD7
- SMR:   Q9PLD7
- GeneID:   1246292
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0167
- TIGR:   TC_0167
- HOGENOM:   HBG728160
- OMA:   QFLYISR
- ProtClustDB:   PRK00730
- BioCyc:   CMUR243161:TC_0167-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13565; Mature: 13565

Theoretical pI: Translated: 12.18; Mature: 12.18

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRLTLPKSARLLKRKQFVYVQRCGQYCRTDQATLRIVPSRHSNIRKVGVTVSKKFGKAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
QRNRFKRIVREAFRHVRPNLPACQVVVSPKGGTLPNFGKLSADLLKHIPEALPLVTSSK
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHRLTLPKSARLLKRKQFVYVQRCGQYCRTDQATLRIVPSRHSNIRKVGVTVSKKFGKAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
QRNRFKRIVREAFRHVRPNLPACQVVVSPKGGTLPNFGKLSADLLKHIPEALPLVTSSK
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935