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The map label for this gene is nisX1 [H]

Identifier: 158340290

GI number: 158340290

Start: 159509

End: 160255

Strand: Direct

Name: nisX1 [H]

Synonym: AM1_C0210

Alternate gene names: 158340290

Gene position: 159509-160255 (Clockwise)

Preceding gene: 158340289

Following gene: 158340291

Centisome position: 58.4

GC content: 44.31

Gene sequence:

>747_bases
GTGGTTCGTCAGTGTCAGTTGCTAGGAGTGAGTCGTTCAAGCCTTTACTACCAGCCGATTGCCCCATCAGGGGAGGAAAT
GACCTTACTCAAACTGATGGACCAACAATATCTAAGAACTCCGTTTTACGGCAGCCGTCGGATGAAAGCTTATTTGCAAA
CCCAAGGCTACACCGTCAATCGTAAGCGGGTTCAACGATTAATGCGTCAGTTAGGACTGCAAGCGATTTATCCCAAACCG
AAACTCAGTGAATCGCATCCCGAGCATCAGATTTACCCTTATTTACTCAGAGGGGTTGATATTGTCTCAGTCAATCAGGT
TTGGAGTACTGATATTACCTATCTCCCTGTGTTTCGAGGGCATTTCTATCTTGTAGCAATTATGGATTGGTTTAGTCGAA
AAGTACTCAGTTGGCGAGTGTCGAACACAATGGATGTGTATTTCTGTCTAGCGGCTCTGGAGGAAGCCTTGAACAAATAT
CCCATCCCTGAGATTTTTAACTCAGATCAAGGGTCACAGTTTACAGCTCATGCTTTTACAGACTGCCTCAAACAGGCCAG
GGTGAACATCAGTATGGACGGTCGAGGCCGTTGTCATGACAATATTTTCATTGAGCGATTATGGCGTTCTGTGAAATGGG
AATTGATTTATCTCAAGGCGTTTGAGGATGGTCAACATTTATCTCAGGAGGTGAAAAATTGGTTTCACTGGTATAACCGA
CAAAGGCCACATCAATTATTAGGCTAA

Upstream 100 bases:

>100_bases
GTCAACTGAAGGTAGAGCGGGATTTTTTAGCCAAGCACTCCGCACGACTGGGTCTGATACCCGAAAGTCCCTGGTAGATG
CTCAGCATCATGCTCTGAGT

Downstream 100 bases:

>100_bases
AAACACCTGATGAAATTTATTATGCGGGTGACTCACCTGTGTAATACTCGTTGAACAAGGCAAACATGGGGAGATTTCTC
AGAGCTTAGAGACCCTGCAA

Product: integrase, catalytic region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MVRQCQLLGVSRSSLYYQPIAPSGEEMTLLKLMDQQYLRTPFYGSRRMKAYLQTQGYTVNRKRVQRLMRQLGLQAIYPKP
KLSESHPEHQIYPYLLRGVDIVSVNQVWSTDITYLPVFRGHFYLVAIMDWFSRKVLSWRVSNTMDVYFCLAALEEALNKY
PIPEIFNSDQGSQFTAHAFTDCLKQARVNISMDGRGRCHDNIFIERLWRSVKWELIYLKAFEDGQHLSQEVKNWFHWYNR
QRPHQLLG

Sequences:

>Translated_248_residues
MVRQCQLLGVSRSSLYYQPIAPSGEEMTLLKLMDQQYLRTPFYGSRRMKAYLQTQGYTVNRKRVQRLMRQLGLQAIYPKP
KLSESHPEHQIYPYLLRGVDIVSVNQVWSTDITYLPVFRGHFYLVAIMDWFSRKVLSWRVSNTMDVYFCLAALEEALNKY
PIPEIFNSDQGSQFTAHAFTDCLKQARVNISMDGRGRCHDNIFIERLWRSVKWELIYLKAFEDGQHLSQEVKNWFHWYNR
QRPHQLLG
>Mature_248_residues
MVRQCQLLGVSRSSLYYQPIAPSGEEMTLLKLMDQQYLRTPFYGSRRMKAYLQTQGYTVNRKRVQRLMRQLGLQAIYPKP
KLSESHPEHQIYPYLLRGVDIVSVNQVWSTDITYLPVFRGHFYLVAIMDWFSRKVLSWRVSNTMDVYFCLAALEEALNKY
PIPEIFNSDQGSQFTAHAFTDCLKQARVNISMDGRGRCHDNIFIERLWRSVKWELIYLKAFEDGQHLSQEVKNWFHWYNR
QRPHQLLG

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=184, Percent_Identity=33.695652173913, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788405, Length=212, Percent_Identity=31.6037735849057, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787263, Length=212, Percent_Identity=31.6037735849057, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786753, Length=212, Percent_Identity=31.6037735849057, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786570, Length=212, Percent_Identity=31.6037735849057, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786490, Length=212, Percent_Identity=31.6037735849057, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789981, Length=204, Percent_Identity=30.3921568627451, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 29438; Mature: 29438

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQCQLLGVSRSSLYYQPIAPSGEEMTLLKLMDQQYLRTPFYGSRRMKAYLQTQGYTVN
CCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEC
RKRVQRLMRQLGLQAIYPKPKLSESHPEHQIYPYLLRGVDIVSVNQVWSTDITYLPVFRG
HHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHCCCCEEEECCHHCCCCEEEEHHCC
HFYLVAIMDWFSRKVLSWRVSNTMDVYFCLAALEEALNKYPIPEIFNSDQGSQFTAHAFT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHH
DCLKQARVNISMDGRGRCHDNIFIERLWRSVKWELIYLKAFEDGQHLSQEVKNWFHWYNR
HHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHCC
QRPHQLLG
CCCHHHCC
>Mature Secondary Structure
MVRQCQLLGVSRSSLYYQPIAPSGEEMTLLKLMDQQYLRTPFYGSRRMKAYLQTQGYTVN
CCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEC
RKRVQRLMRQLGLQAIYPKPKLSESHPEHQIYPYLLRGVDIVSVNQVWSTDITYLPVFRG
HHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHCCCCEEEECCHHCCCCEEEEHHCC
HFYLVAIMDWFSRKVLSWRVSNTMDVYFCLAALEEALNKYPIPEIFNSDQGSQFTAHAFT
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHH
DCLKQARVNISMDGRGRCHDNIFIERLWRSVKWELIYLKAFEDGQHLSQEVKNWFHWYNR
HHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHCC
QRPHQLLG
CCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]