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The map label for this gene is lpd [H]

Identifier: 158318805

GI number: 158318805

Start: 8636606

End: 8636935

Strand: Direct

Name: lpd [H]

Synonym: Franean1_7077

Alternate gene names: 158318805

Gene position: 8636606-8636935 (Clockwise)

Preceding gene: 158318804

Following gene: 158318806

Centisome position: 96.15

GC content: 70.3

Gene sequence:

>330_bases
ATGCCGGATTTCGATCTGCTCGTCCTCGGTGGCGGACCCGGTGGGTACGTCACCGCGATCAGGGCCGCCCAGCACGGCCT
CTCCGTGGGATTGGTGGAGAAGGAACGCCCCGGTGGCGTGTGTCTGAACTGGGGCTGCATCTCCACCAAGGCGATGCTGC
GCTCGGCCGGCCATCGAGGCGACCGGACCCCTGCGAGTGGTCGTGGACGGCCCGGAGCCCACGTCGATCGAGTCGGATGT
CGTCCTGGTGGGGACGGGGTCGCGTCCCCACCACCCGGGACCTCGGGCTCGACGTGGCCGGGGTCACCACCGACCGGCGG
GGTTTCGTGA

Upstream 100 bases:

>100_bases
CAGCTCGGCATGGTCGCGGTGATCCGGATGAAGAACACTCGGCCTTACTGCGGGCGGTGTGTCTTTCCCTGCGGTGACCA
TCGTCGAAGGGCTCACCGGC

Downstream 100 bases:

>100_bases
CAGTCGACGACCGGATGCGGTCTCATTCATCTCGAAAGAAGGTTTCCTATCATGGGTGATCTCGTCCTGGTCCGCCACGG
CGAAACCGAGTGGTCCCTCT

Product: pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)-like protein

Products: NA

Alternate protein names: Dihydrolipoamide dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MPDFDLLVLGGGPGGYVTAIRAAQHGLSVGLVEKERPGGVCLNWGCISTKAMLRSAGHRGDRTPASGRGRPGAHVDRVGC
RPGGDGVASPPPGTSGSTWPGSPPTGGVS

Sequences:

>Translated_109_residues
MPDFDLLVLGGGPGGYVTAIRAAQHGLSVGLVEKERPGGVCLNWGCISTKAMLRSAGHRGDRTPASGRGRPGAHVDRVGC
RPGGDGVASPPPGTSGSTWPGSPPTGGVS
>Mature_108_residues
PDFDLLVLGGGPGGYVTAIRAAQHGLSVGLVEKERPGGVCLNWGCISTKAMLRSAGHRGDRTPASGRGRPGAHVDRVGCR
PGGDGVASPPPGTSGSTWPGSPPTGGVS

Specific function: Lipoamide dehydrogenase is a component of the alpha- ketoacid dehydrogenase complexes [H]

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI32565766, Length=55, Percent_Identity=58.1818181818182, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321091, Length=53, Percent_Identity=52.8301886792453, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR006258
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.4 [H]

Molecular weight: Translated: 10826; Mature: 10695

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFDLLVLGGGPGGYVTAIRAAQHGLSVGLVEKERPGGVCLNWGCISTKAMLRSAGHRG
CCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCHHHHHHHCCCCC
DRTPASGRGRPGAHVDRVGCRPGGDGVASPPPGTSGSTWPGSPPTGGVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDFDLLVLGGGPGGYVTAIRAAQHGLSVGLVEKERPGGVCLNWGCISTKAMLRSAGHRG
CCCCEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCHHHHHHHCCCCC
DRTPASGRGRPGAHVDRVGCRPGGDGVASPPPGTSGSTWPGSPPTGGVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515924 [H]