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The map label for this gene is adrA [H]

Identifier: 157963523

GI number: 157963523

Start: 4517320

End: 4518282

Strand: Direct

Name: adrA [H]

Synonym: Spea_3711

Alternate gene names: 157963523

Gene position: 4517320-4518282 (Clockwise)

Preceding gene: 157963522

Following gene: 157963531

Centisome position: 87.3

GC content: 46.11

Gene sequence:

>963_bases
ATGGATACAAATACAGATCTAACTGCAATGAACGAACTCCACTGGCTAATCGATATGGTGCAAACCATAGAGGTAGGCTT
AGTCGTGCTCGATCGTGATTACAACATCCAGCTGTGGAATGGTTTTATGGAAAACCACAGTGGCGTAGCCCCTAATTCAA
TTAAAGGCAAAAACCTGTTTGAGCAGTTTGATTACCTGCCAGCTACGTGGCTGAAGCAGAAAATGGAGTCGGTTTACCTA
TTAAAGAACCGAGCCTTTATCAGCTGGGAACAGAGACCCTTTGTGTTCCAGTTCAAGAACTATCGGCCGATTACTGGCAG
AGCGGACTTCATGTATCAAAACGTCACTCTGCTGCCGCTGTCATCACTCACTGGTGAAGTGACCCATATCAGTATGATCG
TCTATGACGTCACCGACGTTGCGATCAATAAACTACAGCTAAAGTCGGCCAATGAACGCTTTGAGCATTTAAGCCAGATA
GATGGACTGACTCAGCTATTTAATCGCCGTCATTGGGAACAGTGCTTACAGAAGGAGTTCGATCGCCATGCTCGCTATGG
CAGTGACACCAGCTTAGTGATGCTCGATATCGATCACTTCAAGTCGATCAATGACACCTACGGTCATCAAGCAGGCGATA
AAGTCCTTCAAAACGTGTCACACCTAATTAAAAAATCACTGCGTGAAACCGATTGCGCAGGGCGTTATGGCGGCGAAGAG
TTTGGTGTAGTGCTAGCCAATACCCCTGCGGCTAATGCACGATTCTTTGCCGAACGTTTGCGAAAGAAACTCGAACAATT
AGAGATCTGCTATGAAGAACACATCATTAAGATCACTGTGAGCTTAGGCATATGCGAAATCAAGCCTGAAATCATGGATA
GTGATACTTGGCTGTCATTAGCCGACCAAGCCCTTTATCAGGCGAAAGAAGCTGGCCGCAACTGCACTATCGCTCACGAG
TAA

Upstream 100 bases:

>100_bases
CGCATCGAAGATCATGATATTCAGTGTGATTTATTACTACTGTTTACCGAAGACTCGCTGCCCACACTCAATTATAAGCT
CGGCTACTTGCTGGATTAAG

Downstream 100 bases:

>100_bases
TACCAATCAATATAAATTACTCATGGGCTATAGAAGACGCTAGAAACAAAAATGCCCATCATCTAGATGGGCATTTTTGT
TGGTAAGCTTATGAGCGAAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MDTNTDLTAMNELHWLIDMVQTIEVGLVVLDRDYNIQLWNGFMENHSGVAPNSIKGKNLFEQFDYLPATWLKQKMESVYL
LKNRAFISWEQRPFVFQFKNYRPITGRADFMYQNVTLLPLSSLTGEVTHISMIVYDVTDVAINKLQLKSANERFEHLSQI
DGLTQLFNRRHWEQCLQKEFDRHARYGSDTSLVMLDIDHFKSINDTYGHQAGDKVLQNVSHLIKKSLRETDCAGRYGGEE
FGVVLANTPAANARFFAERLRKKLEQLEICYEEHIIKITVSLGICEIKPEIMDSDTWLSLADQALYQAKEAGRNCTIAHE

Sequences:

>Translated_320_residues
MDTNTDLTAMNELHWLIDMVQTIEVGLVVLDRDYNIQLWNGFMENHSGVAPNSIKGKNLFEQFDYLPATWLKQKMESVYL
LKNRAFISWEQRPFVFQFKNYRPITGRADFMYQNVTLLPLSSLTGEVTHISMIVYDVTDVAINKLQLKSANERFEHLSQI
DGLTQLFNRRHWEQCLQKEFDRHARYGSDTSLVMLDIDHFKSINDTYGHQAGDKVLQNVSHLIKKSLRETDCAGRYGGEE
FGVVLANTPAANARFFAERLRKKLEQLEICYEEHIIKITVSLGICEIKPEIMDSDTWLSLADQALYQAKEAGRNCTIAHE
>Mature_320_residues
MDTNTDLTAMNELHWLIDMVQTIEVGLVVLDRDYNIQLWNGFMENHSGVAPNSIKGKNLFEQFDYLPATWLKQKMESVYL
LKNRAFISWEQRPFVFQFKNYRPITGRADFMYQNVTLLPLSSLTGEVTHISMIVYDVTDVAINKLQLKSANERFEHLSQI
DGLTQLFNRRHWEQCLQKEFDRHARYGSDTSLVMLDIDHFKSINDTYGHQAGDKVLQNVSHLIKKSLRETDCAGRYGGEE
FGVVLANTPAANARFFAERLRKKLEQLEICYEEHIIKITVSLGICEIKPEIMDSDTWLSLADQALYQAKEAGRNCTIAHE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=171, Percent_Identity=39.766081871345, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787262, Length=214, Percent_Identity=34.5794392523364, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=41.7177914110429, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=35.1190476190476, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788381, Length=209, Percent_Identity=31.1004784688995, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081881, Length=186, Percent_Identity=33.8709677419355, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787541, Length=310, Percent_Identity=26.4516129032258, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787802, Length=191, Percent_Identity=31.413612565445, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788085, Length=192, Percent_Identity=30.7291666666667, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=35.2201257861635, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081974, Length=150, Percent_Identity=32, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787056, Length=155, Percent_Identity=29.0322580645161, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 36976; Mature: 36976

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNTDLTAMNELHWLIDMVQTIEVGLVVLDRDYNIQLWNGFMENHSGVAPNSIKGKNLF
CCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEEEHHHHHCCCCCCCCCCCCHHHH
EQFDYLPATWLKQKMESVYLLKNRAFISWEQRPFVFQFKNYRPITGRADFMYQNVTLLPL
HHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCHHEECCEEEEEH
SSLTGEVTHISMIVYDVTDVAINKLQLKSANERFEHLSQIDGLTQLFNRRHWEQCLQKEF
HHHCCCHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRHARYGSDTSLVMLDIDHFKSINDTYGHQAGDKVLQNVSHLIKKSLRETDCAGRYGGEE
HHHHCCCCCCEEEEEEHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
FGVVLANTPAANARFFAERLRKKLEQLEICYEEHIIKITVSLGICEIKPEIMDSDTWLSL
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECHHHCCCCHHHHH
ADQALYQAKEAGRNCTIAHE
HHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MDTNTDLTAMNELHWLIDMVQTIEVGLVVLDRDYNIQLWNGFMENHSGVAPNSIKGKNLF
CCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEEEHHHHHCCCCCCCCCCCCHHHH
EQFDYLPATWLKQKMESVYLLKNRAFISWEQRPFVFQFKNYRPITGRADFMYQNVTLLPL
HHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCHHEECCEEEEEH
SSLTGEVTHISMIVYDVTDVAINKLQLKSANERFEHLSQIDGLTQLFNRRHWEQCLQKEF
HHHCCCHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRHARYGSDTSLVMLDIDHFKSINDTYGHQAGDKVLQNVSHLIKKSLRETDCAGRYGGEE
HHHHCCCCCCEEEEEEHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
FGVVLANTPAANARFFAERLRKKLEQLEICYEEHIIKITVSLGICEIKPEIMDSDTWLSL
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECHHHCCCCHHHHH
ADQALYQAKEAGRNCTIAHE
HHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]