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The map label for this gene is yoeA [H]

Identifier: 157963503

GI number: 157963503

Start: 4490794

End: 4492155

Strand: Direct

Name: yoeA [H]

Synonym: Spea_3691

Alternate gene names: 157963503

Gene position: 4490794-4492155 (Clockwise)

Preceding gene: 157963500

Following gene: 157963504

Centisome position: 86.79

GC content: 52.2

Gene sequence:

>1362_bases
ATGAGAGACAGACACGGGCTGCTAACTCAGCCAATTGGTCGTGTACTGCTAAATATGAGCCTTCCAAACCTGATTGGTAT
CTTAACCATTCTCGGGTTCAGCCTCGTTGACACTTTTTTTATCAGCCAATTAGGTACCGAATCCCTCGCGGCCATCAGCT
TTACCTTCCCGGTAACGCTTATTATCTCTAGCATTGCCATTGGCATTGGCGCAGGAGTGTCGACCAATCTAGGGCGCTTA
ATTGGCGGCGGCCACGCGGATAAGGCCAAGGTATTCTTGCACGACGCCTTGATGCTGACCTTTTTGCTAATTGCCTTTAT
CGCTCTGCTTGGCAGCCTGTGCATCGACCCACTATTTAGCCTGCTTGGGGCCAACGATTCGAGCTTACCGCTGATCCATG
ACTATATGTTTATCTGGTATCTGGGGGCACCGCTGCTAGTGCTGTTGATGGTAGGTAACCAAGGCCTGCGCGCCACCGGA
GATACCCGTTCTCCGGCCAAGATAATGATGCTAGCGGCGCTAATTAACCTTATTCTCGACCCGCTACTGATCTTCGGTAT
CGGGCCTTTTCCGCGCTTAGAGATTGAGGGCGCGGCCATTGCAACTGTGATCTCTTGGGTAGTGGCATTGTCACTGTCGA
CCCATCTGCTGATCTTTAAGCGTCATCTTGTGGATTTCGTTGAGCCCAATATAAAGCGCCTCAAATGCAACTGGAAGCAG
CTGGCACATATTGCTCAGCCAGCGGCGATGATGAATCTGCTAAACCCGCTGGCTAATGCCATTATTATGGCCATGCTGGC
CCGCATCGATCACAGCGCGGTGGCGGCCTTTGGTGCCGGTACCCGTTTAGAGTCGGTGATGCTGATTGCGGTAATGGCAC
TGTCATCTAGCCTAGTGCCGTTTGTGGCGCAAAACTTGGGCGCGGGGCAAACTCAGCGTGCCCGCGGCGCACTGATGCTG
TCACTTAAGTTTGTATTGGTGTTTCAAACCTTGCTGTATCTGCCGCTACTGTTTTTAGCCAAGCCGCTAGCCGAGCTATT
TAGTAGCGACCCGCAAGTGATTGAGTGGCTCACCTTCTATATTCTGGTGCTACCCGCCGCCTATGGCCCACTGGGGATTG
TGATTTTAGTGGCGACCTCGCTTAACGCTTACCACAGGCCAATGAGCTCGCTGGTGTTAAACGTGTGCCGATTATTCCTA
ATAATGCTGCCGCTGGCGGCTTTAGGCTCATACTTGGGTGGCGTTAAAGGCCTACTCTTGGCATTGCCTATCACTAACGC
CATCATGGGTATCGCCTGTTATGTGTTGGCGACACGGATCTCTGAGCCAGAGAAAACCGATATTAAGGTGAGCCAAGCCT
AG

Upstream 100 bases:

>100_bases
ATTTACAAAATAAATCCGTTTTTTTTGACCCGGCCGGATAAAATTTGTGGCAATCCTGATAGAATTCGCCCTCCGAGTAA
AGACTAGGCAAGACTTCCCT

Downstream 100 bases:

>100_bases
TTATGATAAGTAGCCAGAATAAATAGTCTTAATAAGTAGCCGCAATAAATAGTCGTAATAAATCAGCTTAAGGCTATCGC
CAACCACTAAGGAGCAGCAC

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MRDRHGLLTQPIGRVLLNMSLPNLIGILTILGFSLVDTFFISQLGTESLAAISFTFPVTLIISSIAIGIGAGVSTNLGRL
IGGGHADKAKVFLHDALMLTFLLIAFIALLGSLCIDPLFSLLGANDSSLPLIHDYMFIWYLGAPLLVLLMVGNQGLRATG
DTRSPAKIMMLAALINLILDPLLIFGIGPFPRLEIEGAAIATVISWVVALSLSTHLLIFKRHLVDFVEPNIKRLKCNWKQ
LAHIAQPAAMMNLLNPLANAIIMAMLARIDHSAVAAFGAGTRLESVMLIAVMALSSSLVPFVAQNLGAGQTQRARGALML
SLKFVLVFQTLLYLPLLFLAKPLAELFSSDPQVIEWLTFYILVLPAAYGPLGIVILVATSLNAYHRPMSSLVLNVCRLFL
IMLPLAALGSYLGGVKGLLLALPITNAIMGIACYVLATRISEPEKTDIKVSQA

Sequences:

>Translated_453_residues
MRDRHGLLTQPIGRVLLNMSLPNLIGILTILGFSLVDTFFISQLGTESLAAISFTFPVTLIISSIAIGIGAGVSTNLGRL
IGGGHADKAKVFLHDALMLTFLLIAFIALLGSLCIDPLFSLLGANDSSLPLIHDYMFIWYLGAPLLVLLMVGNQGLRATG
DTRSPAKIMMLAALINLILDPLLIFGIGPFPRLEIEGAAIATVISWVVALSLSTHLLIFKRHLVDFVEPNIKRLKCNWKQ
LAHIAQPAAMMNLLNPLANAIIMAMLARIDHSAVAAFGAGTRLESVMLIAVMALSSSLVPFVAQNLGAGQTQRARGALML
SLKFVLVFQTLLYLPLLFLAKPLAELFSSDPQVIEWLTFYILVLPAAYGPLGIVILVATSLNAYHRPMSSLVLNVCRLFL
IMLPLAALGSYLGGVKGLLLALPITNAIMGIACYVLATRISEPEKTDIKVSQA
>Mature_453_residues
MRDRHGLLTQPIGRVLLNMSLPNLIGILTILGFSLVDTFFISQLGTESLAAISFTFPVTLIISSIAIGIGAGVSTNLGRL
IGGGHADKAKVFLHDALMLTFLLIAFIALLGSLCIDPLFSLLGANDSSLPLIHDYMFIWYLGAPLLVLLMVGNQGLRATG
DTRSPAKIMMLAALINLILDPLLIFGIGPFPRLEIEGAAIATVISWVVALSLSTHLLIFKRHLVDFVEPNIKRLKCNWKQ
LAHIAQPAAMMNLLNPLANAIIMAMLARIDHSAVAAFGAGTRLESVMLIAVMALSSSLVPFVAQNLGAGQTQRARGALML
SLKFVLVFQTLLYLPLLFLAKPLAELFSSDPQVIEWLTFYILVLPAAYGPLGIVILVATSLNAYHRPMSSLVLNVCRLFL
IMLPLAALGSYLGGVKGLLLALPITNAIMGIACYVLATRISEPEKTDIKVSQA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=357, Percent_Identity=22.4089635854342, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48678; Mature: 48678

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDRHGLLTQPIGRVLLNMSLPNLIGILTILGFSLVDTFFISQLGTESLAAISFTFPVTL
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IISSIAIGIGAGVSTNLGRLIGGGHADKAKVFLHDALMLTFLLIAFIALLGSLCIDPLFS
HHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGANDSSLPLIHDYMFIWYLGAPLLVLLMVGNQGLRATGDTRSPAKIMMLAALINLILD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLLIFGIGPFPRLEIEGAAIATVISWVVALSLSTHLLIFKRHLVDFVEPNIKRLKCNWKQ
HHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
LAHIAQPAAMMNLLNPLANAIIMAMLARIDHSAVAAFGAGTRLESVMLIAVMALSSSLVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FVAQNLGAGQTQRARGALMLSLKFVLVFQTLLYLPLLFLAKPLAELFSSDPQVIEWLTFY
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ILVLPAAYGPLGIVILVATSLNAYHRPMSSLVLNVCRLFLIMLPLAALGSYLGGVKGLLL
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPITNAIMGIACYVLATRISEPEKTDIKVSQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
>Mature Secondary Structure
MRDRHGLLTQPIGRVLLNMSLPNLIGILTILGFSLVDTFFISQLGTESLAAISFTFPVTL
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IISSIAIGIGAGVSTNLGRLIGGGHADKAKVFLHDALMLTFLLIAFIALLGSLCIDPLFS
HHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGANDSSLPLIHDYMFIWYLGAPLLVLLMVGNQGLRATGDTRSPAKIMMLAALINLILD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLLIFGIGPFPRLEIEGAAIATVISWVVALSLSTHLLIFKRHLVDFVEPNIKRLKCNWKQ
HHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHH
LAHIAQPAAMMNLLNPLANAIIMAMLARIDHSAVAAFGAGTRLESVMLIAVMALSSSLVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FVAQNLGAGQTQRARGALMLSLKFVLVFQTLLYLPLLFLAKPLAELFSSDPQVIEWLTFY
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ILVLPAAYGPLGIVILVATSLNAYHRPMSSLVLNVCRLFLIMLPLAALGSYLGGVKGLLL
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPITNAIMGIACYVLATRISEPEKTDIKVSQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]