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The map label for this gene is tcpI [H]

Identifier: 157963484

GI number: 157963484

Start: 4469014

End: 4470873

Strand: Direct

Name: tcpI [H]

Synonym: Spea_3672

Alternate gene names: 157963484

Gene position: 4469014-4470873 (Clockwise)

Preceding gene: 157963480

Following gene: 157963485

Centisome position: 86.36

GC content: 38.06

Gene sequence:

>1860_bases
ATGTTAAAAAAGATCACCACCTATTTTATTTTGACACTATCATTATTAATGGTATTAAGTTTTTATGTTAGTTATAACTT
TTTTGAATCTTGGAAAAACGCGAATATACAGAAAGAAAACGACACTGTTGTCAATATCCTTAATGGCACTATGTCCAATG
CTTTGGCAAACGCTGAAAATAGCGTTAATAGTTTAGCTAAAACATTTTCAGGTTTTGAGTTTGACGATGAAACCTTGAAT
ATCATGCGCTCAATAGTGACAGAGTCAAAAGGCAAATACATGGGGGTTTACTTCAGTAAACCCGGCGGTGAAACATTCAC
CTACTCGAGTGAAGTCAGTGGACTAATGGAAGGGTTTAACGCTAAACATTTGAATAGAGAATGGTTTATTGTTGCAATGC
AAGGGCGTAACATTGTTTCCCTTCCCTATGTAAGTTCAACTGGTGAAACAATTATTACGGTTTCGTCGCCGATTAGAAAT
AGTGTTAATGCCATTGTGGGCGTGTTAGGTATCGATATCGATATCACTGAAGAGCTTGAAAAAACAAATATTCAATATGT
GATAACAAGTAAAGATGGCCATGTTTTATTTGCGGATTTTAGTGGCGAATCATGGAAAGGTAAGAACATCTATGAATTAA
GACCGCTATACCGAAATGTGAGTCAGGTTCCATTTTCATATCAAAATGATAATGGCGATCACTACAGTGTATCAAGGCAA
GATTTTAATAATCAATATGATGTATTTGCATTTACCCGTCAAAATTCAATAGTAGACAGCAGAAATGAGCTGTTAACGAC
AGTGGTAATACAATTACTCCTTGTTGGCGTGATTTTGGCATTAGTCGTATTCTTTATAGTAAGAAAAGAGATTGATATTA
ATCTAGGAGAAGAGCCTAGAGAGCTGGCTTCGAAAATCCGTATTTTTGCTGAAGGGAATTTGATGGGTGTTGATTTCTCT
CGCACGGGCTTGGTATCTATGTCGCTACGGGATATGCAAGAAAATATCAGGAATATTACCCAGACAACAGGAGCGGTAAC
TGAGTCATTGTTAGAAAACCAAGCCTTAATAGAGTCGATTATTCAAGAGAATAAGAGCAATGCACAAAATGAATCATTAG
AAGTAGACCAAGTCGCATCGGCAATCCTAGAGCTTTCGGCAACAGCTGCTGATGTCGCCCAAAATGCGGTGCTAGCAGAT
ACTCAAACATCTGAAGCGTTAAATGTTGTCACATTAGGCTCTGAAACACTCAGTCGTTCGGAAGTGATTTCAGAGCAAGT
GAACAGCTCTATTAAAGAGTCTGTCATCATAGTCAATGAGCTAAGAGCTTATGCAGAGAAAATTAGTAGCGTTGTACATG
TTATTACTTCAATTTCTGAGCAAACAAACCTACTGGCTTTAAACGCCGCTATTGAGGCTGCAAGAGCTGGTGAACAAGGC
CGTGGCTTTGCCGTCGTTGCCGATGAAGTGCGCTCATTAGCAGCAAAGACCCAACAATCGACCATAGATATTCAAAACAT
TATTAGTCAGCTGCAAGAGCAATCAAAAAAGGCCGACGAATCCATGATTAATAATTCTCACATGGTAGAAGAGTCAAACG
TGATTGCTAAAGAGATCGCCACCGCCTTCAATGAAATTTTAATAAAAGTTGAATCGATTTCAGATATCAATAGATTAGTT
GCTACGGCATCTGAACAGCAGTCAGCTGTTACATTAGATGTTTCTCACCGCGTAGAAAACATCAATGATACTGTGCAGGT
TAGTTTGAATAATGCCCATACCATCAGCGATGTGAATCAAGATATTTCTAGCTTAATTCATAAAGTTAAACAAGAGATGG
CATTCTTTAAAGTCAGTTAG

Upstream 100 bases:

>100_bases
ACCATATTGTCGCCTTAGGTAGAACGTCATTCTATTGATTAGATTTCGCTGAACTCAATTAATTATGACATCATAATTCT
TATATTTAGGGCTTAGCGCT

Downstream 100 bases:

>100_bases
TCCTACACATTGGCAAAAGCCTTATCACTGAACACTGCTGCGGTATCAATAACATTGTTGATACCGCACTTTATCTCCAC
ACTCATAAAGCTACGCATCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MLKKITTYFILTLSLLMVLSFYVSYNFFESWKNANIQKENDTVVNILNGTMSNALANAENSVNSLAKTFSGFEFDDETLN
IMRSIVTESKGKYMGVYFSKPGGETFTYSSEVSGLMEGFNAKHLNREWFIVAMQGRNIVSLPYVSSTGETIITVSSPIRN
SVNAIVGVLGIDIDITEELEKTNIQYVITSKDGHVLFADFSGESWKGKNIYELRPLYRNVSQVPFSYQNDNGDHYSVSRQ
DFNNQYDVFAFTRQNSIVDSRNELLTTVVIQLLLVGVILALVVFFIVRKEIDINLGEEPRELASKIRIFAEGNLMGVDFS
RTGLVSMSLRDMQENIRNITQTTGAVTESLLENQALIESIIQENKSNAQNESLEVDQVASAILELSATAADVAQNAVLAD
TQTSEALNVVTLGSETLSRSEVISEQVNSSIKESVIIVNELRAYAEKISSVVHVITSISEQTNLLALNAAIEAARAGEQG
RGFAVVADEVRSLAAKTQQSTIDIQNIISQLQEQSKKADESMINNSHMVEESNVIAKEIATAFNEILIKVESISDINRLV
ATASEQQSAVTLDVSHRVENINDTVQVSLNNAHTISDVNQDISSLIHKVKQEMAFFKVS

Sequences:

>Translated_619_residues
MLKKITTYFILTLSLLMVLSFYVSYNFFESWKNANIQKENDTVVNILNGTMSNALANAENSVNSLAKTFSGFEFDDETLN
IMRSIVTESKGKYMGVYFSKPGGETFTYSSEVSGLMEGFNAKHLNREWFIVAMQGRNIVSLPYVSSTGETIITVSSPIRN
SVNAIVGVLGIDIDITEELEKTNIQYVITSKDGHVLFADFSGESWKGKNIYELRPLYRNVSQVPFSYQNDNGDHYSVSRQ
DFNNQYDVFAFTRQNSIVDSRNELLTTVVIQLLLVGVILALVVFFIVRKEIDINLGEEPRELASKIRIFAEGNLMGVDFS
RTGLVSMSLRDMQENIRNITQTTGAVTESLLENQALIESIIQENKSNAQNESLEVDQVASAILELSATAADVAQNAVLAD
TQTSEALNVVTLGSETLSRSEVISEQVNSSIKESVIIVNELRAYAEKISSVVHVITSISEQTNLLALNAAIEAARAGEQG
RGFAVVADEVRSLAAKTQQSTIDIQNIISQLQEQSKKADESMINNSHMVEESNVIAKEIATAFNEILIKVESISDINRLV
ATASEQQSAVTLDVSHRVENINDTVQVSLNNAHTISDVNQDISSLIHKVKQEMAFFKVS
>Mature_619_residues
MLKKITTYFILTLSLLMVLSFYVSYNFFESWKNANIQKENDTVVNILNGTMSNALANAENSVNSLAKTFSGFEFDDETLN
IMRSIVTESKGKYMGVYFSKPGGETFTYSSEVSGLMEGFNAKHLNREWFIVAMQGRNIVSLPYVSSTGETIITVSSPIRN
SVNAIVGVLGIDIDITEELEKTNIQYVITSKDGHVLFADFSGESWKGKNIYELRPLYRNVSQVPFSYQNDNGDHYSVSRQ
DFNNQYDVFAFTRQNSIVDSRNELLTTVVIQLLLVGVILALVVFFIVRKEIDINLGEEPRELASKIRIFAEGNLMGVDFS
RTGLVSMSLRDMQENIRNITQTTGAVTESLLENQALIESIIQENKSNAQNESLEVDQVASAILELSATAADVAQNAVLAD
TQTSEALNVVTLGSETLSRSEVISEQVNSSIKESVIIVNELRAYAEKISSVVHVITSISEQTNLLALNAAIEAARAGEQG
RGFAVVADEVRSLAAKTQQSTIDIQNIISQLQEQSKKADESMINNSHMVEESNVIAKEIATAFNEILIKVESISDINRLV
ATASEQQSAVTLDVSHRVENINDTVQVSLNNAHTISDVNQDISSLIHKVKQEMAFFKVS

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=345, Percent_Identity=28.4057971014493, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=32.2368421052632, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788195, Length=273, Percent_Identity=31.1355311355311, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788194, Length=266, Percent_Identity=31.203007518797, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=267, Percent_Identity=28.4644194756554, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68409; Mature: 68409

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKITTYFILTLSLLMVLSFYVSYNFFESWKNANIQKENDTVVNILNGTMSNALANAEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
SVNSLAKTFSGFEFDDETLNIMRSIVTESKGKYMGVYFSKPGGETFTYSSEVSGLMEGFN
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHHCCC
AKHLNREWFIVAMQGRNIVSLPYVSSTGETIITVSSPIRNSVNAIVGVLGIDIDITEELE
CCCCCCEEEEEEECCCCEEEECEECCCCCEEEEECCHHHHHHHHHHHHHCCCEEEHHHHH
KTNIQYVITSKDGHVLFADFSGESWKGKNIYELRPLYRNVSQVPFSYQNDNGDHYSVSRQ
HCCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEEEEHH
DFNNQYDVFAFTRQNSIVDSRNELLTTVVIQLLLVGVILALVVFFIVRKEIDINLGEEPR
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ELASKIRIFAEGNLMGVDFSRTGLVSMSLRDMQENIRNITQTTGAVTESLLENQALIESI
HHHHHEEEEECCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQENKSNAQNESLEVDQVASAILELSATAADVAQNAVLADTQTSEALNVVTLGSETLSRS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEECCHHHHHH
EVISEQVNSSIKESVIIVNELRAYAEKISSVVHVITSISEQTNLLALNAAIEAARAGEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCC
RGFAVVADEVRSLAAKTQQSTIDIQNIISQLQEQSKKADESMINNSHMVEESNVIAKEIA
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TAFNEILIKVESISDINRLVATASEQQSAVTLDVSHRVENINDTVQVSLNNAHTISDVNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCEEEEEECCCCCHHHHHH
DISSLIHKVKQEMAFFKVS
HHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MLKKITTYFILTLSLLMVLSFYVSYNFFESWKNANIQKENDTVVNILNGTMSNALANAEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
SVNSLAKTFSGFEFDDETLNIMRSIVTESKGKYMGVYFSKPGGETFTYSSEVSGLMEGFN
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHHCCC
AKHLNREWFIVAMQGRNIVSLPYVSSTGETIITVSSPIRNSVNAIVGVLGIDIDITEELE
CCCCCCEEEEEEECCCCEEEECEECCCCCEEEEECCHHHHHHHHHHHHHCCCEEEHHHHH
KTNIQYVITSKDGHVLFADFSGESWKGKNIYELRPLYRNVSQVPFSYQNDNGDHYSVSRQ
HCCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEEEEHH
DFNNQYDVFAFTRQNSIVDSRNELLTTVVIQLLLVGVILALVVFFIVRKEIDINLGEEPR
HCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ELASKIRIFAEGNLMGVDFSRTGLVSMSLRDMQENIRNITQTTGAVTESLLENQALIESI
HHHHHEEEEECCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQENKSNAQNESLEVDQVASAILELSATAADVAQNAVLADTQTSEALNVVTLGSETLSRS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEEECCHHHHHH
EVISEQVNSSIKESVIIVNELRAYAEKISSVVHVITSISEQTNLLALNAAIEAARAGEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCC
RGFAVVADEVRSLAAKTQQSTIDIQNIISQLQEQSKKADESMINNSHMVEESNVIAKEIA
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TAFNEILIKVESISDINRLVATASEQQSAVTLDVSHRVENINDTVQVSLNNAHTISDVNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCEEEEEECCCCCHHHHHH
DISSLIHKVKQEMAFFKVS
HHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]