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The map label for this gene is yieG [C]

Identifier: 157963474

GI number: 157963474

Start: 4454085

End: 4455455

Strand: Direct

Name: yieG [C]

Synonym: Spea_3662

Alternate gene names: 157963474

Gene position: 4454085-4455455 (Clockwise)

Preceding gene: 157963472

Following gene: 157963480

Centisome position: 86.08

GC content: 48.43

Gene sequence:

>1371_bases
GTGGCGATCTCTAGCTTACTTCAACGTGCGGGTAAGTCCCGTTTTCTGGACTCAACCTTCAAGCTTTCACAGCGCAAGGC
CAATGTTGGCACCGAGCTATATGCAGGCTTTATTACCTTCTTAGCCATGAGCTATATTTTGGCGGTGAACCCAGCAATCT
TAGGTAGCATCGATGGGATGGATAAGGGTGCGATCTTTACCGCCACCGCACTCGCCGCCGCACTTGCCACCTTGATAATG
GGTTTTTTCGGTAACTATCCAGTGATGTTGGCGCCGGGCATGAGTATGAACGGCTTCTTTAAGGGCATGCTAGCATCGAG
CTCTGTGGCACTTATCTGGCACGAAGCCCTGTTCGGTATTTTCCTGTCTGGTATCGTCTATCTAATCTTTTCGATGACTA
AGATCCGCAAGCAGATGATTGAGTCGATCCCAGAAGATCTAAAACTTGCCATCACAGTGTCTTTAGGTCTATTTATCGCC
TTCCTCGGGCTGAAGAACGCCGGCATTATTGTCGCAAACCCTGTAGTGATGGTCAGTATGGGCGATATCACCCAGCCACA
AGTTGCCATCGCCTTTATCAGCTTGTTTGTCGCAGTCGGCTGCATGGTGAGAAATATCAAACTGGCCACCTTTATCGCCT
TTATGACCTCAATAACTCTCACGCTTATCAGCGATGCAGTGCTAGGCACTAAATATGCGCCGATCCCTGAAAATTGGTTC
AGTGTGCCGCCTAGCATAGAGCCTAGCTTTGGTAAGGTGTTTAACTTTGAATTTTTAACCGTCGACAAGCTATTTGATCT
ACTGTTTATCGTTATCATCTTCTTTATCGTCGACTTCTTCGACGGCTTATCGACGATTGTCGGCGTAGGTAAAGATGCAG
GCATTATTGATAAAGATGGCAAGGTACCTAACGCCCGCGCAGCACTAGTAGCCGATGCTGGCGGCACGGTAATTGGCAGC
GTACTGGGCACCACATCCATTACGGCGTTTTCAGAGTCTGGTATCGCCTCGGCGCAAGGTGCTAAAACGGGCTTAGCGGC
AGTAGCCACCGCGATACTGTTCCTACTGGCTCTGTTCTGCTACCCAGTGTTCTCAATGTTCTCTACCGCTATCGTTGCAC
CCGCAATGATCGTAGTGGGGATTTATATGATAGGTCGTTTAGGGCAAATAAACTGGGATCATAAACCTTCGTGTATTGCC
GCCTTCTTCACCATGATGTTCACGATTTTGAGCTTCTCACCAGCTAACGGCATGGCTATGGGCTTTATCAGTTACGCATT
TGCCATGGTGGTGGCCGGTAAAGGCCGTGAAGTTCATCCAATCATCTATGGCTTATCACTGATCTTTATCACTTACCTTG
TGATGCTCTAG

Upstream 100 bases:

>100_bases
AACGTTTAAAACACTTGGCAGGCCAGTGGTATCTGCCAATAAATTTATTGAACTCTTCGCGTATAAGAAAATTAGCGCAT
CAATAAAATAAGGCATCACT

Downstream 100 bases:

>100_bases
TTGAGATAAGCCTTAGCCGCATAAAAAAAGGGTCTGCAATGCAGACCCTTTTCTTTGTTCCAAACCAATTAATTTACTGG
TAGATGACTAACCTTAACTA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAISSLLQRAGKSRFLDSTFKLSQRKANVGTELYAGFITFLAMSYILAVNPAILGSIDGMDKGAIFTATALAAALATLIM
GFFGNYPVMLAPGMSMNGFFKGMLASSSVALIWHEALFGIFLSGIVYLIFSMTKIRKQMIESIPEDLKLAITVSLGLFIA
FLGLKNAGIIVANPVVMVSMGDITQPQVAIAFISLFVAVGCMVRNIKLATFIAFMTSITLTLISDAVLGTKYAPIPENWF
SVPPSIEPSFGKVFNFEFLTVDKLFDLLFIVIIFFIVDFFDGLSTIVGVGKDAGIIDKDGKVPNARAALVADAGGTVIGS
VLGTTSITAFSESGIASAQGAKTGLAAVATAILFLLALFCYPVFSMFSTAIVAPAMIVVGIYMIGRLGQINWDHKPSCIA
AFFTMMFTILSFSPANGMAMGFISYAFAMVVAGKGREVHPIIYGLSLIFITYLVML

Sequences:

>Translated_456_residues
MAISSLLQRAGKSRFLDSTFKLSQRKANVGTELYAGFITFLAMSYILAVNPAILGSIDGMDKGAIFTATALAAALATLIM
GFFGNYPVMLAPGMSMNGFFKGMLASSSVALIWHEALFGIFLSGIVYLIFSMTKIRKQMIESIPEDLKLAITVSLGLFIA
FLGLKNAGIIVANPVVMVSMGDITQPQVAIAFISLFVAVGCMVRNIKLATFIAFMTSITLTLISDAVLGTKYAPIPENWF
SVPPSIEPSFGKVFNFEFLTVDKLFDLLFIVIIFFIVDFFDGLSTIVGVGKDAGIIDKDGKVPNARAALVADAGGTVIGS
VLGTTSITAFSESGIASAQGAKTGLAAVATAILFLLALFCYPVFSMFSTAIVAPAMIVVGIYMIGRLGQINWDHKPSCIA
AFFTMMFTILSFSPANGMAMGFISYAFAMVVAGKGREVHPIIYGLSLIFITYLVML
>Mature_455_residues
AISSLLQRAGKSRFLDSTFKLSQRKANVGTELYAGFITFLAMSYILAVNPAILGSIDGMDKGAIFTATALAAALATLIMG
FFGNYPVMLAPGMSMNGFFKGMLASSSVALIWHEALFGIFLSGIVYLIFSMTKIRKQMIESIPEDLKLAITVSLGLFIAF
LGLKNAGIIVANPVVMVSMGDITQPQVAIAFISLFVAVGCMVRNIKLATFIAFMTSITLTLISDAVLGTKYAPIPENWFS
VPPSIEPSFGKVFNFEFLTVDKLFDLLFIVIIFFIVDFFDGLSTIVGVGKDAGIIDKDGKVPNARAALVADAGGTVIGSV
LGTTSITAFSESGIASAQGAKTGLAAVATAILFLLALFCYPVFSMFSTAIVAPAMIVVGIYMIGRLGQINWDHKPSCIAA
FFTMMFTILSFSPANGMAMGFISYAFAMVVAGKGREVHPIIYGLSLIFITYLVML

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=459, Percent_Identity=36.3834422657952, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87082309, Length=431, Percent_Identity=34.5707656612529, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1790499, Length=441, Percent_Identity=28.5714285714286, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI48994909, Length=430, Percent_Identity=26.9767441860465, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48602; Mature: 48470

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISSLLQRAGKSRFLDSTFKLSQRKANVGTELYAGFITFLAMSYILAVNPAILGSIDGM
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
DKGAIFTATALAAALATLIMGFFGNYPVMLAPGMSMNGFFKGMLASSSVALIWHEALFGI
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHH
FLSGIVYLIFSMTKIRKQMIESIPEDLKLAITVSLGLFIAFLGLKNAGIIVANPVVMVSM
HHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHCCCCCEEEECCEEEEEE
GDITQPQVAIAFISLFVAVGCMVRNIKLATFIAFMTSITLTLISDAVLGTKYAPIPENWF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SVPPSIEPSFGKVFNFEFLTVDKLFDLLFIVIIFFIVDFFDGLSTIVGVGKDAGIIDKDG
CCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVPNARAALVADAGGTVIGSVLGTTSITAFSESGIASAQGAKTGLAAVATAILFLLALFC
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YPVFSMFSTAIVAPAMIVVGIYMIGRLGQINWDHKPSCIAAFFTMMFTILSFSPANGMAM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
GFISYAFAMVVAGKGREVHPIIYGLSLIFITYLVML
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AISSLLQRAGKSRFLDSTFKLSQRKANVGTELYAGFITFLAMSYILAVNPAILGSIDGM
CHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
DKGAIFTATALAAALATLIMGFFGNYPVMLAPGMSMNGFFKGMLASSSVALIWHEALFGI
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHH
FLSGIVYLIFSMTKIRKQMIESIPEDLKLAITVSLGLFIAFLGLKNAGIIVANPVVMVSM
HHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHHCCCCCEEEECCEEEEEE
GDITQPQVAIAFISLFVAVGCMVRNIKLATFIAFMTSITLTLISDAVLGTKYAPIPENWF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SVPPSIEPSFGKVFNFEFLTVDKLFDLLFIVIIFFIVDFFDGLSTIVGVGKDAGIIDKDG
CCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVPNARAALVADAGGTVIGSVLGTTSITAFSESGIASAQGAKTGLAAVATAILFLLALFC
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YPVFSMFSTAIVAPAMIVVGIYMIGRLGQINWDHKPSCIAAFFTMMFTILSFSPANGMAM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
GFISYAFAMVVAGKGREVHPIIYGLSLIFITYLVML
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]