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The map label for this gene is add [H]

Identifier: 157963207

GI number: 157963207

Start: 4147086

End: 4148081

Strand: Direct

Name: add [H]

Synonym: Spea_3392

Alternate gene names: 157963207

Gene position: 4147086-4148081 (Clockwise)

Preceding gene: 157963206

Following gene: 157963208

Centisome position: 80.14

GC content: 44.38

Gene sequence:

>996_bases
ATGAATTATCTACAGCTACCCAAAATCGATCTTCACTGCCACTTAGACGGAAGTGTTCGTCCGCAAACCGTTATCGACCT
TGCTAAACTTCAAGACGTTACTATCCCAAGTTTTAACGTCGATGACATTAAAGCTTTAATGGTGGCTCCCGCATCTTGCC
CGAATCTCGATGAATACCTAACCCGCTTTGCACTGCCAGTTTCTGTGATGCAAACAGAAGCGGCGCTTGAGCGTATCTCG
TTCGAGCTTTTTGAAGATGCGGCTAAAGAGAATGTGAAGTACCTAGAGGTACGTTTTGGCCCGCAACTTCATCAAAAAAT
GAGTCTGAACTTCGAGCAGATTATTGGCAGTGTCGTTAAAGGTATGCGCAGAGCTGAAGCACAGTACGACATCAAAGGTA
ACTACATATTATCGATCATTAAGGTACTACCAAAAGATGATATCAATGATGTTATCGATGCCGGTGCTAAGTTCCTCAAC
AACGGTGTGGTCGCTTTTGACTTAGCCGCTAGCGAAGAGCCAGGCTTCTGCCACGAGTACATTCCTTACGCCAAGTATGC
TCTAGAAAAAGGCTATAGAATCACCATTCACGCTGGTGAGCAAGGTGTCGGCCAAAATGTGTATGATGCTATCTCACTTT
TAGGCGCCGAGCGCATCGGTCATGGCATTCATATCAATAGCCACCAACAAGCTTACGAATTAGTTAAAACAGAAGCCGTA
GCACTCGAAACCTGCCCTAGCAGTAACGTGCAAACTAAAGCGGTTGAAAGCATAGAGAGTCACCCATTTGGAGACTTCTA
CCGCGATGGTTTGTTGGTCACCATTAACACTGATAACCGTACCGTGTCAGACACGACAATGACCAAAGAGCTACAGCTTG
CAGCTGAGAAGTTTAACTTAACTGAAGCAGACTATTTTGCCATCTATAAGATGAGTGTCGACAATGCGTTTACATCCGAC
GAAGTGAAACTGTCTCTATTAAAATTTATCGATTAA

Upstream 100 bases:

>100_bases
TATGTAATGCTAATTTAACAAGTTTAGTGCTTTGTTGCTGTGCAACATGTGAGCGCTGATGGACTTAGATGGGTATAACC
ACTTAATAAAGGAGAGCTTC

Downstream 100 bases:

>100_bases
CCTTTATCGGTTTCTTATCTCAGGACGGGACAGACAAACTAAAAAAGCCTATTGGTTCAATCAATAGGCTTTTGTGTCTG
TACCAATCTAATTAAAACAC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MNYLQLPKIDLHCHLDGSVRPQTVIDLAKLQDVTIPSFNVDDIKALMVAPASCPNLDEYLTRFALPVSVMQTEAALERIS
FELFEDAAKENVKYLEVRFGPQLHQKMSLNFEQIIGSVVKGMRRAEAQYDIKGNYILSIIKVLPKDDINDVIDAGAKFLN
NGVVAFDLAASEEPGFCHEYIPYAKYALEKGYRITIHAGEQGVGQNVYDAISLLGAERIGHGIHINSHQQAYELVKTEAV
ALETCPSSNVQTKAVESIESHPFGDFYRDGLLVTINTDNRTVSDTTMTKELQLAAEKFNLTEADYFAIYKMSVDNAFTSD
EVKLSLLKFID

Sequences:

>Translated_331_residues
MNYLQLPKIDLHCHLDGSVRPQTVIDLAKLQDVTIPSFNVDDIKALMVAPASCPNLDEYLTRFALPVSVMQTEAALERIS
FELFEDAAKENVKYLEVRFGPQLHQKMSLNFEQIIGSVVKGMRRAEAQYDIKGNYILSIIKVLPKDDINDVIDAGAKFLN
NGVVAFDLAASEEPGFCHEYIPYAKYALEKGYRITIHAGEQGVGQNVYDAISLLGAERIGHGIHINSHQQAYELVKTEAV
ALETCPSSNVQTKAVESIESHPFGDFYRDGLLVTINTDNRTVSDTTMTKELQLAAEKFNLTEADYFAIYKMSVDNAFTSD
EVKLSLLKFID
>Mature_331_residues
MNYLQLPKIDLHCHLDGSVRPQTVIDLAKLQDVTIPSFNVDDIKALMVAPASCPNLDEYLTRFALPVSVMQTEAALERIS
FELFEDAAKENVKYLEVRFGPQLHQKMSLNFEQIIGSVVKGMRRAEAQYDIKGNYILSIIKVLPKDDINDVIDAGAKFLN
NGVVAFDLAASEEPGFCHEYIPYAKYALEKGYRITIHAGEQGVGQNVYDAISLLGAERIGHGIHINSHQQAYELVKTEAV
ALETCPSSNVQTKAVESIESHPFGDFYRDGLLVTINTDNRTVSDTTMTKELQLAAEKFNLTEADYFAIYKMSVDNAFTSD
EVKLSLLKFID

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=347, Percent_Identity=26.5129682997118, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI226693318, Length=335, Percent_Identity=25.0746268656716, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1787910, Length=325, Percent_Identity=28.9230769230769, Blast_Score=158, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17538512, Length=345, Percent_Identity=32.1739130434783, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565969, Length=345, Percent_Identity=32.1739130434783, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI115537133, Length=325, Percent_Identity=24.9230769230769, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324188, Length=331, Percent_Identity=23.8670694864048, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645260, Length=327, Percent_Identity=26.9113149847095, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36921; Mature: 36921

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLQLPKIDLHCHLDGSVRPQTVIDLAKLQDVTIPSFNVDDIKALMVAPASCPNLDEYL
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHEECCCCCCCHHHHH
TRFALPVSVMQTEAALERISFELFEDAAKENVKYLEVRFGPQLHQKMSLNFEQIIGSVVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHH
GMRRAEAQYDIKGNYILSIIKVLPKDDINDVIDAGAKFLNNGVVAFDLAASEEPGFCHEY
HHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHH
IPYAKYALEKGYRITIHAGEQGVGQNVYDAISLLGAERIGHGIHINSHQQAYELVKTEAV
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHH
ALETCPSSNVQTKAVESIESHPFGDFYRDGLLVTINTDNRTVSDTTMTKELQLAAEKFNL
EEECCCCCCCHHHHHHHHHCCCCCCHHHCCEEEEEECCCCEECCHHHHHHHHHHHHHCCC
TEADYFAIYKMSVDNAFTSDEVKLSLLKFID
CCCCEEEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNYLQLPKIDLHCHLDGSVRPQTVIDLAKLQDVTIPSFNVDDIKALMVAPASCPNLDEYL
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHEECCCCCCCHHHHH
TRFALPVSVMQTEAALERISFELFEDAAKENVKYLEVRFGPQLHQKMSLNFEQIIGSVVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHH
GMRRAEAQYDIKGNYILSIIKVLPKDDINDVIDAGAKFLNNGVVAFDLAASEEPGFCHEY
HHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHH
IPYAKYALEKGYRITIHAGEQGVGQNVYDAISLLGAERIGHGIHINSHQQAYELVKTEAV
HHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHH
ALETCPSSNVQTKAVESIESHPFGDFYRDGLLVTINTDNRTVSDTTMTKELQLAAEKFNL
EEECCCCCCCHHHHHHHHHCCCCCCHHHCCEEEEEECCCCEECCHHHHHHHHHHHHHCCC
TEADYFAIYKMSVDNAFTSDEVKLSLLKFID
CCCCEEEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA