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The map label for this gene is ygfA [H]

Identifier: 157963127

GI number: 157963127

Start: 4053775

End: 4054404

Strand: Direct

Name: ygfA [H]

Synonym: Spea_3311

Alternate gene names: 157963127

Gene position: 4053775-4054404 (Clockwise)

Preceding gene: 157963124

Following gene: 157963128

Centisome position: 78.34

GC content: 49.21

Gene sequence:

>630_bases
ATGCCATCACAGCTGCCGTCTCAGTTTTCATCCACAGCCAATATTCAATCGACTCGCAAAGCGCTTCGCCTGCAGATCCG
TCAAGCTCGGCGATCATTGTCGGATGAGCAGCAGCTTGCTTGTTCACAATTGGCAGCCAAGCACACACTGGAGGCGCTAA
TATCACGCAAGGTCAAGTGTGTGGCCTTGTATCTAAGTAATGATGGCGAACTCGATACGCAACCATTAATCGATGGGCTT
TGGCAAAACGGGGTTGATGTTTACCTCCCTAGACTGCACCCCTTCAGCGCAGGAAACTTGCTATTTTTGCGCTACGACAA
AGGTACCCAACTGCTAAAGAATCACTTGGGGATTTGGGAGCCAAAACTGGATATCACTCAGATGATCCTCACTCATCAGC
TGGATGTGGTGATCACGCCGTTAGTCGCCTTTGATCTGCAAGGCAACAGAATGGGCATGGGCGGTGGTTATTATGATAGA
AGCCTCAGCAATTGGCAGCAGCAACATAGACCTTTGCCTATCGGCTATGCCCATGATTGCCAACAAGTCGAGGCCCTGCC
ATGTGAGCATTGGGATGTACCTTTGCCATTTATTTTCACTCCTAGTCACTGCTATAGCTTTGAGCAATAG

Upstream 100 bases:

>100_bases
CGTCTTAGCTGTTCCTAGAACCTAAGACCTTTCTTTGCCTTCCCTAGGATCTTCTTTTGTATGCTAAGCTGCTTAGGTTA
TTGATAGGAGAGCCTATGTT

Downstream 100 bases:

>100_bases
TAGTTATTAGACTTATTACTGCTGAAAGGAATTTGTTTAAGCCTTTCAGCTATATGCTTTGCTCTCATATCACTTAAAAA
CAACAAGTTACAAATCACCA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MPSQLPSQFSSTANIQSTRKALRLQIRQARRSLSDEQQLACSQLAAKHTLEALISRKVKCVALYLSNDGELDTQPLIDGL
WQNGVDVYLPRLHPFSAGNLLFLRYDKGTQLLKNHLGIWEPKLDITQMILTHQLDVVITPLVAFDLQGNRMGMGGGYYDR
SLSNWQQQHRPLPIGYAHDCQQVEALPCEHWDVPLPFIFTPSHCYSFEQ

Sequences:

>Translated_209_residues
MPSQLPSQFSSTANIQSTRKALRLQIRQARRSLSDEQQLACSQLAAKHTLEALISRKVKCVALYLSNDGELDTQPLIDGL
WQNGVDVYLPRLHPFSAGNLLFLRYDKGTQLLKNHLGIWEPKLDITQMILTHQLDVVITPLVAFDLQGNRMGMGGGYYDR
SLSNWQQQHRPLPIGYAHDCQQVEALPCEHWDVPLPFIFTPSHCYSFEQ
>Mature_208_residues
PSQLPSQFSSTANIQSTRKALRLQIRQARRSLSDEQQLACSQLAAKHTLEALISRKVKCVALYLSNDGELDTQPLIDGLW
QNGVDVYLPRLHPFSAGNLLFLRYDKGTQLLKNHLGIWEPKLDITQMILTHQLDVVITPLVAFDLQGNRMGMGGGYYDRS
LSNWQQQHRPLPIGYAHDCQQVEALPCEHWDVPLPFIFTPSHCYSFEQ

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=26.5625, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1789278, Length=182, Percent_Identity=55.4945054945055, Blast_Score=204, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6321031, Length=202, Percent_Identity=29.7029702970297, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI161077430, Length=200, Percent_Identity=30, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23770; Mature: 23638

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSQLPSQFSSTANIQSTRKALRLQIRQARRSLSDEQQLACSQLAAKHTLEALISRKVKC
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEE
VALYLSNDGELDTQPLIDGLWQNGVDVYLPRLHPFSAGNLLFLRYDKGTQLLKNHLGIWE
EEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHCCCCCC
PKLDITQMILTHQLDVVITPLVAFDLQGNRMGMGGGYYDRSLSNWQQQHRPLPIGYAHDC
CCHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCH
QQVEALPCEHWDVPLPFIFTPSHCYSFEQ
HHHHCCCCCCCCCCCCEEECCHHHCCCCC
>Mature Secondary Structure 
PSQLPSQFSSTANIQSTRKALRLQIRQARRSLSDEQQLACSQLAAKHTLEALISRKVKC
CCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEE
VALYLSNDGELDTQPLIDGLWQNGVDVYLPRLHPFSAGNLLFLRYDKGTQLLKNHLGIWE
EEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHCCCCCC
PKLDITQMILTHQLDVVITPLVAFDLQGNRMGMGGGYYDRSLSNWQQQHRPLPIGYAHDC
CCHHHHHHHHHHHHHHHHHHHHEEECCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCH
QQVEALPCEHWDVPLPFIFTPSHCYSFEQ
HHHHCCCCCCCCCCCCEEECCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]