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The map label for this gene is nadD

Identifier: 157962963

GI number: 157962963

Start: 3851974

End: 3852624

Strand: Direct

Name: nadD

Synonym: Spea_3146

Alternate gene names: 157962963

Gene position: 3851974-3852624 (Clockwise)

Preceding gene: 157962962

Following gene: 157962964

Centisome position: 74.44

GC content: 47.31

Gene sequence:

>651_bases
ATGAAAATAGGCATTTTAGGTGGCACATTCGACCCGATCCACTTTGGCCATATCCGTCCGGCCCAAGAGGTGAAGCAGCA
GCTTAAGTTAGATGAGGTTTGGTTAATGCCAAACCACATCCCGCCCCATAAGCAAGGTACCCACGTTTCTAGTCAAGCTC
GGCTCGCCATGGCAGAACTTATCGCCGATGAGTTCCCCTGCTTCAAAGTGTGCGATATTGAGGCTAAGCGAGACACTCCC
TCCTATAGCGCAATGACGTTAACCCAGCTCACTAAGATTTATCCTCAGCATGAATTCTATTTCATCATGGGAATGGACTC
ATTTTTAAGCTTTACTCGTTGGCATGAGTGGCAACAGCTGTTTGGCCTGTGCCATCTAGTCGTCTGTAAGCGTCCTGGAT
GGCTGCTTGATGATAAAGATCCAATGCAAAAGATCTTAACCCCACGACTCCATGATGTCGCTAGGCCTTTACCAGCCAAG
TCTGGCAAGATCTTTATGGTCGATATCACACAGCAAGATATCTCTTCAACTCAGGTGCGACAGCAACTGATGCAAGGCAT
AATGCCTAGTGCCGTACTCCCTACTTCTATTCAAGAGTACATCCGACACAATCGTCTTTATCGAGGCGACTCATCAACGA
AAACCGATTAA

Upstream 100 bases:

>100_bases
TAAAGCAGCAAGGAATAGAAGATTGGACAGGGCTAAGCCATATCAGCTTATTGTTCGATGCCAAGGCCCATAACAAGCTG
GCACATATCGCGTTAGACTA

Downstream 100 bases:

>100_bases
AGCCTAATCAAACCCAGATATTTATGCCAATAGCTATTAATCTGGATTTGAAATACTGCTATACTATCGCGCTGTCTTAA
AATTAATGGGGTACCAGCGT

Product: nicotinate (nicotinamide) nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKIGILGGTFDPIHFGHIRPAQEVKQQLKLDEVWLMPNHIPPHKQGTHVSSQARLAMAELIADEFPCFKVCDIEAKRDTP
SYSAMTLTQLTKIYPQHEFYFIMGMDSFLSFTRWHEWQQLFGLCHLVVCKRPGWLLDDKDPMQKILTPRLHDVARPLPAK
SGKIFMVDITQQDISSTQVRQQLMQGIMPSAVLPTSIQEYIRHNRLYRGDSSTKTD

Sequences:

>Translated_216_residues
MKIGILGGTFDPIHFGHIRPAQEVKQQLKLDEVWLMPNHIPPHKQGTHVSSQARLAMAELIADEFPCFKVCDIEAKRDTP
SYSAMTLTQLTKIYPQHEFYFIMGMDSFLSFTRWHEWQQLFGLCHLVVCKRPGWLLDDKDPMQKILTPRLHDVARPLPAK
SGKIFMVDITQQDISSTQVRQQLMQGIMPSAVLPTSIQEYIRHNRLYRGDSSTKTD
>Mature_216_residues
MKIGILGGTFDPIHFGHIRPAQEVKQQLKLDEVWLMPNHIPPHKQGTHVSSQARLAMAELIADEFPCFKVCDIEAKRDTP
SYSAMTLTQLTKIYPQHEFYFIMGMDSFLSFTRWHEWQQLFGLCHLVVCKRPGWLLDDKDPMQKILTPRLHDVARPLPAK
SGKIFMVDITQQDISSTQVRQQLMQGIMPSAVLPTSIQEYIRHNRLYRGDSSTKTD

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=208, Percent_Identity=34.6153846153846, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_SHEPA (A8H7C5)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001502997.1
- ProteinModelPortal:   A8H7C5
- SMR:   A8H7C5
- STRING:   A8H7C5
- GeneID:   5663535
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_3146
- NMPDR:   fig|398579.3.peg.2725
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   LLGWDAF
- ProtClustDB:   CLSK906129
- BioCyc:   SPEA398579:SPEA_3146-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 24888; Mature: 24888

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGILGGTFDPIHFGHIRPAQEVKQQLKLDEVWLMPNHIPPHKQGTHVSSQARLAMAEL
CEEEEECCCCCCCCCCCCCCHHHHHHHHCHHHEEECCCCCCCCCCCCCCHHHHHHHHHHH
IADEFPCFKVCDIEAKRDTPSYSAMTLTQLTKIYPQHEFYFIMGMDSFLSFTRWHEWQQL
HHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
FGLCHLVVCKRPGWLLDDKDPMQKILTPRLHDVARPLPAKSGKIFMVDITQQDISSTQVR
HHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
QQLMQGIMPSAVLPTSIQEYIRHNRLYRGDSSTKTD
HHHHHCCCCCCCCHHHHHHHHHHCCEECCCCCCCCC
>Mature Secondary Structure
MKIGILGGTFDPIHFGHIRPAQEVKQQLKLDEVWLMPNHIPPHKQGTHVSSQARLAMAEL
CEEEEECCCCCCCCCCCCCCHHHHHHHHCHHHEEECCCCCCCCCCCCCCHHHHHHHHHHH
IADEFPCFKVCDIEAKRDTPSYSAMTLTQLTKIYPQHEFYFIMGMDSFLSFTRWHEWQQL
HHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
FGLCHLVVCKRPGWLLDDKDPMQKILTPRLHDVARPLPAKSGKIFMVDITQQDISSTQVR
HHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
QQLMQGIMPSAVLPTSIQEYIRHNRLYRGDSSTKTD
HHHHHCCCCCCCCHHHHHHHHHHCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA