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The map label for this gene is dcp [H]

Identifier: 157962671

GI number: 157962671

Start: 3481063

End: 3483198

Strand: Direct

Name: dcp [H]

Synonym: Spea_2852

Alternate gene names: 157962671

Gene position: 3481063-3483198 (Clockwise)

Preceding gene: 157962666

Following gene: 157962675

Centisome position: 67.27

GC content: 48.69

Gene sequence:

>2136_bases
ATGCATAAGACAATCATTGCTGCGGCCATTGCCGCCACCTTAGCCTTGAGTGGCTGCTCATCAACAGCTCCGTCTCAAAG
TTCGTCGGTAGAGATGGTGCAAAGTCAAAACCCATTCCTTCAAGCAAGCAAGTTGCAATATGAGGCGCCAGACTTCACTC
TGATAAAAGATGAGCATTTTCAGCCTGCACTAGAGCTTGGGATCAAAGAGCATTATCAAGAGATCTTAACCATAGCTAAC
AACCCTAAGGCGGCAACGTTTGAAAACACCATTGTGGCGATGGAGAAAAGCGGCGAACTACTCAACCGTACCTCAAAAGT
GTTCTACAACTTAACTGGATCGAACAGTAATCCAGAACTGCGCAAAATACAGGGCGAAATGGCCCCAAAAATGGCCGCCC
ACTCAGATAATATCAATCTCAACCCTGCTCTATTTAAACGGATTGAGAGCCTCTATAAACAACGTGCGGATCTGAGCTTA
TCAGCGGAAGAAAATCGCTTAGTCGAGGTTTACTACAAGCGCTTTGTTCGCGCTGGTGCCAAGCTCACAGAAGATCAAAA
ACAGCAGATCCGAGTGCTCAATGAAGAGCAATCGACTCTGACCAATGAGTTTGCTCAGCGTTTAATGCGCCAGACAAAAG
AGATTGCCGTCGTCGTCGACAGCAAGGAGCTACTAACTGGTTTGTCTGACAGCGCTATCCGCGCAGCAGCACAAGATGCA
AAAGCAGCAGGCCATGAAGGTAAGTATCAACTTAATATTACCAATACCACTCGCCAACCCGTTTTGACTCAGTTACAAGA
CCGGGAGTTGCGTCAACAGATCTGGCAAGCCTCTGCTAATCGTGGTCTTGAGGGTGATAATGAAACAGCCTCTTTAGTTG
CTCGTCTAGCCCAACTGCGCGCCGAGCGAGCAGAGCTGCTTGGCTATGAAAACTGGGCCGAGTATCGCCTAGAGCCACAG
ATGGCTAAGACCCCAGAAGCGGTTTATAAGATGTTTGGCTCTATGGTGCCAGCTGTTGTTAAGAACACGCAAAAAGAAGC
CAGCGATATTCAAGCCATGATCGACAAAACTGGCGGCGATTTTGAGCTAGCACCTTGGGACTGGGCTTATTACGCCGAAT
TAGTACGTAAAGAGAAGTTCGACCTAGATGAGAACGCCATCCGCCCCTATTTTGAATTTGACCGTGTACTTGAAGACGGC
GTGTTCTTTACCCTCAAAGAGCTCTACGGCGTAACGCTAAAGCCACGCCCTGATCTGCCTGTTTACCATGAAGATGTGAA
AGCCTACGAGATGTTTGATGAAGATGGTAGCAGCATGGCGATCTTCTATGCCGATTACTTCTCTCGTGAAGGCAAGCGAG
GTGGTGCATGGATGAGCTCGTTCGTGACGCAGTCGGAGTTACTTAATAGCAAGCCCGTTGTCGTTAACGTGATGAACATT
AAGAAGGCGCCAGCAGGCGAGCCAACTTTTGTCAGCTACGATGAAGTGACTACCATGTTCCATGAGATGGGCCACGGCAC
CCACGGCATGTTCTCGAAAGTCGTTTATCCAACTCTTTCAGGTACCGCGGTTTCACGTGACTTTGTTGAGTTTCCATCAA
CCTTCGAGGAAGATTGGGCTGCACATCCAAAAGTATTAGCCAACTATGCTAAGCACTATGAAACGGGTGAGCCTATCCCG
CAGGAGCTACTCAGCAAGCTATTAAAATCGCGCAGCTTTAACCAAGGTTTCGACACCTTAGAGTATATGTCTGCCGCTCT
TTTAGATCTTGAATGGCATACACTCAAGGCCGGTAGCCCACTGCAAGATGTTGCCAGCTTTGAGGCGGCAGCGCTTAAGA
AGCACGGCGTCGATCTTGCTGCGGTTCCACCTCGCTATAAGTCGACCTACTTTGCCCACGCTTTCCCAGGTGGTTACTCT
GCAAGCTACTACGCTTATATGTGGAGTGAAATCTTAGCGGCAGATGCCTTCGCCTACGTACAAACACAGGGCGGCTTAAA
TCGCGAAATAGGTATGAAGTTTAGAAAGACCATTCGTGAAGTGGGCAACACCGTTGCGCCTATGGATGCCTATAAGGCTT
TCAGAGGCCAAGAGCCAACAACCGATGCCTTGTTAGAGCGTCGTGGCTTAAACTAA

Upstream 100 bases:

>100_bases
AAAACCATGCATCTGCGCACAAAATCAATCAAATTAAGACACGTTTAATACTCAAATATTAGATTAAAAGCACAATTATA
ATAAAGGAAGTCAAAAATCT

Downstream 100 bases:

>100_bases
GGCTAAGTCAGTTTATTGCTTGCCGATGTCATGATAAATGGCTCCCTTTAAAGGGAGCTTTTTTTATGGCTGAGCTAGAT
AAATTCAGCCCACAAAAAAA

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MHKTIIAAAIAATLALSGCSSTAPSQSSSVEMVQSQNPFLQASKLQYEAPDFTLIKDEHFQPALELGIKEHYQEILTIAN
NPKAATFENTIVAMEKSGELLNRTSKVFYNLTGSNSNPELRKIQGEMAPKMAAHSDNINLNPALFKRIESLYKQRADLSL
SAEENRLVEVYYKRFVRAGAKLTEDQKQQIRVLNEEQSTLTNEFAQRLMRQTKEIAVVVDSKELLTGLSDSAIRAAAQDA
KAAGHEGKYQLNITNTTRQPVLTQLQDRELRQQIWQASANRGLEGDNETASLVARLAQLRAERAELLGYENWAEYRLEPQ
MAKTPEAVYKMFGSMVPAVVKNTQKEASDIQAMIDKTGGDFELAPWDWAYYAELVRKEKFDLDENAIRPYFEFDRVLEDG
VFFTLKELYGVTLKPRPDLPVYHEDVKAYEMFDEDGSSMAIFYADYFSREGKRGGAWMSSFVTQSELLNSKPVVVNVMNI
KKAPAGEPTFVSYDEVTTMFHEMGHGTHGMFSKVVYPTLSGTAVSRDFVEFPSTFEEDWAAHPKVLANYAKHYETGEPIP
QELLSKLLKSRSFNQGFDTLEYMSAALLDLEWHTLKAGSPLQDVASFEAAALKKHGVDLAAVPPRYKSTYFAHAFPGGYS
ASYYAYMWSEILAADAFAYVQTQGGLNREIGMKFRKTIREVGNTVAPMDAYKAFRGQEPTTDALLERRGLN

Sequences:

>Translated_711_residues
MHKTIIAAAIAATLALSGCSSTAPSQSSSVEMVQSQNPFLQASKLQYEAPDFTLIKDEHFQPALELGIKEHYQEILTIAN
NPKAATFENTIVAMEKSGELLNRTSKVFYNLTGSNSNPELRKIQGEMAPKMAAHSDNINLNPALFKRIESLYKQRADLSL
SAEENRLVEVYYKRFVRAGAKLTEDQKQQIRVLNEEQSTLTNEFAQRLMRQTKEIAVVVDSKELLTGLSDSAIRAAAQDA
KAAGHEGKYQLNITNTTRQPVLTQLQDRELRQQIWQASANRGLEGDNETASLVARLAQLRAERAELLGYENWAEYRLEPQ
MAKTPEAVYKMFGSMVPAVVKNTQKEASDIQAMIDKTGGDFELAPWDWAYYAELVRKEKFDLDENAIRPYFEFDRVLEDG
VFFTLKELYGVTLKPRPDLPVYHEDVKAYEMFDEDGSSMAIFYADYFSREGKRGGAWMSSFVTQSELLNSKPVVVNVMNI
KKAPAGEPTFVSYDEVTTMFHEMGHGTHGMFSKVVYPTLSGTAVSRDFVEFPSTFEEDWAAHPKVLANYAKHYETGEPIP
QELLSKLLKSRSFNQGFDTLEYMSAALLDLEWHTLKAGSPLQDVASFEAAALKKHGVDLAAVPPRYKSTYFAHAFPGGYS
ASYYAYMWSEILAADAFAYVQTQGGLNREIGMKFRKTIREVGNTVAPMDAYKAFRGQEPTTDALLERRGLN
>Mature_711_residues
MHKTIIAAAIAATLALSGCSSTAPSQSSSVEMVQSQNPFLQASKLQYEAPDFTLIKDEHFQPALELGIKEHYQEILTIAN
NPKAATFENTIVAMEKSGELLNRTSKVFYNLTGSNSNPELRKIQGEMAPKMAAHSDNINLNPALFKRIESLYKQRADLSL
SAEENRLVEVYYKRFVRAGAKLTEDQKQQIRVLNEEQSTLTNEFAQRLMRQTKEIAVVVDSKELLTGLSDSAIRAAAQDA
KAAGHEGKYQLNITNTTRQPVLTQLQDRELRQQIWQASANRGLEGDNETASLVARLAQLRAERAELLGYENWAEYRLEPQ
MAKTPEAVYKMFGSMVPAVVKNTQKEASDIQAMIDKTGGDFELAPWDWAYYAELVRKEKFDLDENAIRPYFEFDRVLEDG
VFFTLKELYGVTLKPRPDLPVYHEDVKAYEMFDEDGSSMAIFYADYFSREGKRGGAWMSSFVTQSELLNSKPVVVNVMNI
KKAPAGEPTFVSYDEVTTMFHEMGHGTHGMFSKVVYPTLSGTAVSRDFVEFPSTFEEDWAAHPKVLANYAKHYETGEPIP
QELLSKLLKSRSFNQGFDTLEYMSAALLDLEWHTLKAGSPLQDVASFEAAALKKHGVDLAAVPPRYKSTYFAHAFPGGYS
ASYYAYMWSEILAADAFAYVQTQGGLNREIGMKFRKTIREVGNTVAPMDAYKAFRGQEPTTDALLERRGLN

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=606, Percent_Identity=28.7128712871287, Blast_Score=237, Evalue=4e-62,
Organism=Homo sapiens, GI14149738, Length=611, Percent_Identity=29.2962356792144, Blast_Score=206, Evalue=6e-53,
Organism=Homo sapiens, GI156105687, Length=628, Percent_Identity=23.8853503184713, Blast_Score=166, Evalue=7e-41,
Organism=Escherichia coli, GI1787819, Length=678, Percent_Identity=44.9852507374631, Blast_Score=628, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=684, Percent_Identity=31.2865497076023, Blast_Score=349, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI32565901, Length=639, Percent_Identity=21.5962441314554, Blast_Score=94, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319793, Length=675, Percent_Identity=26.6666666666667, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6322715, Length=580, Percent_Identity=23.2758620689655, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21356111, Length=577, Percent_Identity=21.6637781629116, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI20129717, Length=416, Percent_Identity=26.6826923076923, Blast_Score=145, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 79843; Mature: 79843

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKTIIAAAIAATLALSGCSSTAPSQSSSVEMVQSQNPFLQASKLQYEAPDFTLIKDEHF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCEEHHCCEECCCCEEEECCCCC
QPALELGIKEHYQEILTIANNPKAATFENTIVAMEKSGELLNRTSKVFYNLTGSNSNPEL
CHHHHHHHHHHHHHHHHHCCCCCCCEECCEEEEEECCCHHHHHHHHEEEEECCCCCCCHH
RKIQGEMAPKMAAHSDNINLNPALFKRIESLYKQRADLSLSAEENRLVEVYYKRFVRAGA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCC
KLTEDQKQQIRVLNEEQSTLTNEFAQRLMRQTKEIAVVVDSKELLTGLSDSAIRAAAQDA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHHHH
KAAGHEGKYQLNITNTTRQPVLTQLQDRELRQQIWQASANRGLEGDNETASLVARLAQLR
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AERAELLGYENWAEYRLEPQMAKTPEAVYKMFGSMVPAVVKNTQKEASDIQAMIDKTGGD
HHHHHHCCCCCHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FELAPWDWAYYAELVRKEKFDLDENAIRPYFEFDRVLEDGVFFTLKELYGVTLKPRPDLP
EEECCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
VYHEDVKAYEMFDEDGSSMAIFYADYFSREGKRGGAWMSSFVTQSELLNSKPVVVNVMNI
CHHHHHHHHHHHCCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEC
KKAPAGEPTFVSYDEVTTMFHEMGHGTHGMFSKVVYPTLSGTAVSRDFVEFPSTFEEDWA
CCCCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHC
AHPKVLANYAKHYETGEPIPQELLSKLLKSRSFNQGFDTLEYMSAALLDLEWHTLKAGSP
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCCC
LQDVASFEAAALKKHGVDLAAVPPRYKSTYFAHAFPGGYSASYYAYMWSEILAADAFAYV
HHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHE
QTQGGLNREIGMKFRKTIREVGNTVAPMDAYKAFRGQEPTTDALLERRGLN
ECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MHKTIIAAAIAATLALSGCSSTAPSQSSSVEMVQSQNPFLQASKLQYEAPDFTLIKDEHF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCEEHHCCEECCCCEEEECCCCC
QPALELGIKEHYQEILTIANNPKAATFENTIVAMEKSGELLNRTSKVFYNLTGSNSNPEL
CHHHHHHHHHHHHHHHHHCCCCCCCEECCEEEEEECCCHHHHHHHHEEEEECCCCCCCHH
RKIQGEMAPKMAAHSDNINLNPALFKRIESLYKQRADLSLSAEENRLVEVYYKRFVRAGA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCC
KLTEDQKQQIRVLNEEQSTLTNEFAQRLMRQTKEIAVVVDSKELLTGLSDSAIRAAAQDA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHHHH
KAAGHEGKYQLNITNTTRQPVLTQLQDRELRQQIWQASANRGLEGDNETASLVARLAQLR
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AERAELLGYENWAEYRLEPQMAKTPEAVYKMFGSMVPAVVKNTQKEASDIQAMIDKTGGD
HHHHHHCCCCCHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FELAPWDWAYYAELVRKEKFDLDENAIRPYFEFDRVLEDGVFFTLKELYGVTLKPRPDLP
EEECCCCHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
VYHEDVKAYEMFDEDGSSMAIFYADYFSREGKRGGAWMSSFVTQSELLNSKPVVVNVMNI
CHHHHHHHHHHHCCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEC
KKAPAGEPTFVSYDEVTTMFHEMGHGTHGMFSKVVYPTLSGTAVSRDFVEFPSTFEEDWA
CCCCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHC
AHPKVLANYAKHYETGEPIPQELLSKLLKSRSFNQGFDTLEYMSAALLDLEWHTLKAGSP
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCCC
LQDVASFEAAALKKHGVDLAAVPPRYKSTYFAHAFPGGYSASYYAYMWSEILAADAFAYV
HHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHE
QTQGGLNREIGMKFRKTIREVGNTVAPMDAYKAFRGQEPTTDALLERRGLN
ECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]