Click here to switch to the map view.

The map label for this gene is aroC [H]

Identifier: 157962409

GI number: 157962409

Start: 3151216

End: 3152310

Strand: Reverse

Name: aroC [H]

Synonym: Spea_2588

Alternate gene names: 157962409

Gene position: 3152310-3151216 (Counterclockwise)

Preceding gene: 157962410

Following gene: 157962408

Centisome position: 60.92

GC content: 48.58

Gene sequence:

>1095_bases
ATGTCGGGAAACAGTATAGGTCAAAATTTCGTAGTAACAACATTCGGTGAAAGCCACGGTGTCGCCATCGGCTGTATTAT
CGACGGATGCCCACCAGGGGTTGAGTTGACAGAGGCGGATATGCAGCACGACTTAGATCGCCGCCGCCCTGGTACTTCAC
GATATACAACTGCTCGAAGAGAGCCTGACGAAGTGCGTATTCTGTCCGGTGTGTTTGAGGGGGAAACCACAGGTACCTCA
ATTGGTTTACTGATTGAAAACACCGACCAGCGCAGCAAAGATTATTCTAATATCAAAGATTTGTTCCGTCCAGGGCATGC
CGACTACACTTACCAACAAAAATACGGTCAACGCGACTATCGCGGTGGCGGTCGTTCATCTGCTCGCGAAACGGCAATGC
GAGTCGCAGCTGGCGCTGTCGCTAAAAAATACCTAAAACAAGTTCATGGCGTTGAAATTCATGCTTATCTGTCACAGCTT
GGGCCGATTGCAGCCGAGACTGTCGATTTTGATCAGATAGAGCAAAATGCCTTTTTCTTTCCTGATGCCACAAAACTGGA
TTCACTAGACGAGTACATGCGTGAGCTTAAAAAGAGTGGGGACTCCATTGGCGCAAAAGTGTCTGTAGTCGCAACGGGTG
TGCCAGTGGGTCTTGGTGAGCCAGTATTTGATCGCTTGGATGCCGATATCGCTCATGCGCTAATGGGCATTAATGCTGTT
AAAGGCGTTGAGATTGGTGATGGTTTTGAAGTGGTGAATCAAAAAGGCTCTGAACATAGAGACTTGATGTCACCAGCAGG
TTTTGCCTCCAATCATGCGGGTGGCATTTTAGGCGGGATCTCTTCTGGTCAGCCAATTATTGCCCATATTGCTATGAAGC
CGACTTCGAGTATTAGCGTGCCGGGTGAGAGCATGAATGCTCAGGGTGAAGTCGCCGAGGTTATCACTAAAGGGCGTCAC
GATCCTTGTGTGGGTATTAGAGCGGTACCAATTGCCGAAGCCATGTTGGCTATCGTGCTGATGGATCACTTATTACGTCA
CCGCGCACAAAATATGGATGTGAATAGCAGTACACCTATTATCGGAATGCGTTGA

Upstream 100 bases:

>100_bases
GGCAATCTGTACTCCTACATTTAGGTTGGTATTGAAGGAATTTACCGATAGAACGCGGGTAAATAAAAATTAGAAAAAGA
GAAAGAGGGCTAAAAAGCGA

Downstream 100 bases:

>100_bases
TGTTTCAACCCAAAAGCACAGAGCAGCAACTTCGCTGGCTCTGTGCCTGTTATTTCTTTTTCTTTTCCATCTTGGGCATC
ATGGTGCCTTATCTGGGAGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGETTGTS
IGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQL
GPIAAETVDFDQIEQNAFFFPDATKLDSLDEYMRELKKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
KGVEIGDGFEVVNQKGSEHRDLMSPAGFASNHAGGILGGISSGQPIIAHIAMKPTSSISVPGESMNAQGEVAEVITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPIIGMR

Sequences:

>Translated_364_residues
MSGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGETTGTS
IGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQL
GPIAAETVDFDQIEQNAFFFPDATKLDSLDEYMRELKKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
KGVEIGDGFEVVNQKGSEHRDLMSPAGFASNHAGGILGGISSGQPIIAHIAMKPTSSISVPGESMNAQGEVAEVITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPIIGMR
>Mature_363_residues
SGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGETTGTSI
GLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQLG
PIAAETVDFDQIEQNAFFFPDATKLDSLDEYMRELKKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAVK
GVEIGDGFEVVNQKGSEHRDLMSPAGFASNHAGGILGGISSGQPIIAHIAMKPTSSISVPGESMNAQGEVAEVITKGRHD
PCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPIIGMR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=76.8802228412256, Blast_Score=551, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6321290, Length=372, Percent_Identity=44.0860215053763, Blast_Score=294, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39048; Mature: 38916

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARR
CCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDEVRILSGVFEGETTGTSIGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQLGPIAAETVDFDQIEQNAFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCHHHHHCCEEEC
PDATKLDSLDEYMRELKKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFEVVNQKGSEHRDLMSPAGFASNHAGGILGGISSGQPIIAHIAMKPTSSISV
CCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCC
PGESMNAQGEVAEVITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPI
CCCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IGMR
EECC
>Mature Secondary Structure 
SGNSIGQNFVVTTFGESHGVAIGCIIDGCPPGVELTEADMQHDLDRRRPGTSRYTTARR
CCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDEVRILSGVFEGETTGTSIGLLIENTDQRSKDYSNIKDLFRPGHADYTYQQKYGQRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKQVHGVEIHAYLSQLGPIAAETVDFDQIEQNAFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCHHHHHCCEEEC
PDATKLDSLDEYMRELKKSGDSIGAKVSVVATGVPVGLGEPVFDRLDADIAHALMGINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFEVVNQKGSEHRDLMSPAGFASNHAGGILGGISSGQPIIAHIAMKPTSSISV
CCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCC
PGESMNAQGEVAEVITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNMDVNSSTPI
CCCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IGMR
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA