Click here to switch to the map view.

The map label for this gene is yegE [C]

Identifier: 157962322

GI number: 157962322

Start: 3045885

End: 3047243

Strand: Direct

Name: yegE [C]

Synonym: Spea_2501

Alternate gene names: 157962322

Gene position: 3045885-3047243 (Clockwise)

Preceding gene: 157962321

Following gene: 157962325

Centisome position: 58.86

GC content: 41.8

Gene sequence:

>1359_bases
ATGACCAACATAGAACAAGCGCTCGCCCTACTCGCTGCACCTTATACAGATGAACACTTCTTTGCTCGCGCCCTAAAGGC
GTTAACCTTAGTGACCGGTTGCCGCTGGGCAGGATTTGGCCGCCCTTCCGCTCAGGAGGGATACGGTGAAATAATTGCTT
TTTTCGATGGTAATGAAAATTTACCTAGTTTTGAATTTGAACTAAAAGGTTCCCCTTGCGAGCAGGTTTACCAGAACAAT
CAATGCCACTTGATCTTTAACAGCGACCTTCAGAAGCTCTTTCCCAATTTTGATTTGATAAAAACACTTGGCGCAGACAG
TTATCAAGCAGAGCAAATATTAAACGAAAAGGGAGGAATGATCGGCCATATCTTCGTACTTGATCCGAAACCGCAAAAAG
AAGACTGTAAATCAAATGAGTTTTTCAGACTCGTTGCCCAGCGAATTGGGGTTGAATATCAGCGGCATATCATTACTCAA
GAACTTGAGCAGCGACAGAAGATGATCGCTTTATCAGAGCAGTATATGTCATTTGTCGATACCGACTATATTTACCGTGT
TGTATCGAAAGGCTATGAGTCACTATTTAACTTAACTCAAGAGCAGATCATCGGAAAGAGTGTTTTCGAACTACATGGCA
GAAACGTATTTGAAAATCAAATAAAACCGCTACTCGATCGTTGCTTTCGAGGAGAACAGATAAAAACTCAAATTTGGGTC
CACCCACCTAACCATAAAAGGCCGATTTTCTTAGATGTTCACCATAATCCTTACTTCGATGCCTACGGTCAAATACAGGG
TTCTATCGTTTCGGCTCATAATATTACTGAGCTTGAACAAGCTAAGAGCAGAATAGAGTATATAGCAAATCACGATAGCC
TAACGGGGCTAGCCAACAGGCGCTCGTTATTTTACCAATTCGAGAAGTTACTTAAAGTGGAAGAAAATGCTAGCCCAACT
GTCGCCATCGCCTATTTAGATATTGACCATTTTAAATCAATTAACGACAACTATGGCCACCAAATTGGCGACCTAGTGCT
CATCGAAGTGGCTGAAATATTAACTCGTGCGAGCTTACAAGGTGATACTGTTGCCCGAATTGGTGGGGACGAATTTATTT
TAATCAAAACTTTTGAGCAACAGCTCGCCACATTAAATGGACAAGTCTTGCTCGATAATCTGCGAATACAACTGCAACAT
GCATTGTGTACTCAGGTTTCAATTGGTGGTCACAAGATAAAAATTAGCGCAAGTATCGGACTTCACTTAGTCGATGACAC
ATCTGCGGAATTAGCTTCACTCATAAATCAGGCCGATAATGAAATGTTTAAATACAAACAAGGCGCACCCGGTCGCTAA

Upstream 100 bases:

>100_bases
CTCGTTAGCAAGCTTAATTAAGTGAATAATAACATTAACATCAATTGAATTAGCTCTGATTTATGGATTAACTGACTGTA
TATGCATCTGGGACAGGGAT

Downstream 100 bases:

>100_bases
TAATACCAAGTTTTCTTATGCATTCGTTTGTAGCATCTCGCCATCAGATTTCGATATGCAGGGCACTTGACACTAACGCC
TACATACCAATGCTTAACCG

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTNIEQALALLAAPYTDEHFFARALKALTLVTGCRWAGFGRPSAQEGYGEIIAFFDGNENLPSFEFELKGSPCEQVYQNN
QCHLIFNSDLQKLFPNFDLIKTLGADSYQAEQILNEKGGMIGHIFVLDPKPQKEDCKSNEFFRLVAQRIGVEYQRHIITQ
ELEQRQKMIALSEQYMSFVDTDYIYRVVSKGYESLFNLTQEQIIGKSVFELHGRNVFENQIKPLLDRCFRGEQIKTQIWV
HPPNHKRPIFLDVHHNPYFDAYGQIQGSIVSAHNITELEQAKSRIEYIANHDSLTGLANRRSLFYQFEKLLKVEENASPT
VAIAYLDIDHFKSINDNYGHQIGDLVLIEVAEILTRASLQGDTVARIGGDEFILIKTFEQQLATLNGQVLLDNLRIQLQH
ALCTQVSIGGHKIKISASIGLHLVDDTSAELASLINQADNEMFKYKQGAPGR

Sequences:

>Translated_452_residues
MTNIEQALALLAAPYTDEHFFARALKALTLVTGCRWAGFGRPSAQEGYGEIIAFFDGNENLPSFEFELKGSPCEQVYQNN
QCHLIFNSDLQKLFPNFDLIKTLGADSYQAEQILNEKGGMIGHIFVLDPKPQKEDCKSNEFFRLVAQRIGVEYQRHIITQ
ELEQRQKMIALSEQYMSFVDTDYIYRVVSKGYESLFNLTQEQIIGKSVFELHGRNVFENQIKPLLDRCFRGEQIKTQIWV
HPPNHKRPIFLDVHHNPYFDAYGQIQGSIVSAHNITELEQAKSRIEYIANHDSLTGLANRRSLFYQFEKLLKVEENASPT
VAIAYLDIDHFKSINDNYGHQIGDLVLIEVAEILTRASLQGDTVARIGGDEFILIKTFEQQLATLNGQVLLDNLRIQLQH
ALCTQVSIGGHKIKISASIGLHLVDDTSAELASLINQADNEMFKYKQGAPGR
>Mature_451_residues
TNIEQALALLAAPYTDEHFFARALKALTLVTGCRWAGFGRPSAQEGYGEIIAFFDGNENLPSFEFELKGSPCEQVYQNNQ
CHLIFNSDLQKLFPNFDLIKTLGADSYQAEQILNEKGGMIGHIFVLDPKPQKEDCKSNEFFRLVAQRIGVEYQRHIITQE
LEQRQKMIALSEQYMSFVDTDYIYRVVSKGYESLFNLTQEQIIGKSVFELHGRNVFENQIKPLLDRCFRGEQIKTQIWVH
PPNHKRPIFLDVHHNPYFDAYGQIQGSIVSAHNITELEQAKSRIEYIANHDSLTGLANRRSLFYQFEKLLKVEENASPTV
AIAYLDIDHFKSINDNYGHQIGDLVLIEVAEILTRASLQGDTVARIGGDEFILIKTFEQQLATLNGQVLLDNLRIQLQHA
LCTQVSIGGHKIKISASIGLHLVDDTSAELASLINQADNEMFKYKQGAPGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=272, Percent_Identity=27.5735294117647, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787541, Length=269, Percent_Identity=28.6245353159851, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=32.0441988950276, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081881, Length=181, Percent_Identity=29.8342541436464, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082007, Length=176, Percent_Identity=31.25, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786584, Length=190, Percent_Identity=27.3684210526316, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788956, Length=178, Percent_Identity=32.5842696629214, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=36.094674556213, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=29.1925465838509, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787262, Length=180, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081974, Length=84, Percent_Identity=36.9047619047619, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788085, Length=108, Percent_Identity=35.1851851851852, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 51285; Mature: 51154

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIEQALALLAAPYTDEHFFARALKALTLVTGCRWAGFGRPSAQEGYGEIIAFFDGNEN
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCC
LPSFEFELKGSPCEQVYQNNQCHLIFNSDLQKLFPNFDLIKTLGADSYQAEQILNEKGGM
CCCEEEEECCCCHHHHHCCCCEEEEECCCHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCE
IGHIFVLDPKPQKEDCKSNEFFRLVAQRIGVEYQRHIITQELEQRQKMIALSEQYMSFVD
EEEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDYIYRVVSKGYESLFNLTQEQIIGKSVFELHGRNVFENQIKPLLDRCFRGEQIKTQIWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEE
HPPNHKRPIFLDVHHNPYFDAYGQIQGSIVSAHNITELEQAKSRIEYIANHDSLTGLANR
ECCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHH
RSLFYQFEKLLKVEENASPTVAIAYLDIDHFKSINDNYGHQIGDLVLIEVAEILTRASLQ
HHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
GDTVARIGGDEFILIKTFEQQLATLNGQVLLDNLRIQLQHALCTQVSIGGHKIKISASIG
CCCEEEECCCCEEEEEEHHHHHHHCCCEEEEEHHHHHHHHHHHHEEECCCEEEEEEEEEC
LHLVDDTSAELASLINQADNEMFKYKQGAPGR
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNIEQALALLAAPYTDEHFFARALKALTLVTGCRWAGFGRPSAQEGYGEIIAFFDGNEN
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCC
LPSFEFELKGSPCEQVYQNNQCHLIFNSDLQKLFPNFDLIKTLGADSYQAEQILNEKGGM
CCCEEEEECCCCHHHHHCCCCEEEEECCCHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCE
IGHIFVLDPKPQKEDCKSNEFFRLVAQRIGVEYQRHIITQELEQRQKMIALSEQYMSFVD
EEEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDYIYRVVSKGYESLFNLTQEQIIGKSVFELHGRNVFENQIKPLLDRCFRGEQIKTQIWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEE
HPPNHKRPIFLDVHHNPYFDAYGQIQGSIVSAHNITELEQAKSRIEYIANHDSLTGLANR
ECCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHH
RSLFYQFEKLLKVEENASPTVAIAYLDIDHFKSINDNYGHQIGDLVLIEVAEILTRASLQ
HHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
GDTVARIGGDEFILIKTFEQQLATLNGQVLLDNLRIQLQHALCTQVSIGGHKIKISASIG
CCCEEEECCCCEEEEEEHHHHHHHCCCEEEEEHHHHHHHHHHHHEEECCCEEEEEEEEEC
LHLVDDTSAELASLINQADNEMFKYKQGAPGR
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]