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The map label for this gene is nreC [H]

Identifier: 157962120

GI number: 157962120

Start: 2791252

End: 2791917

Strand: Direct

Name: nreC [H]

Synonym: Spea_2299

Alternate gene names: 157962120

Gene position: 2791252-2791917 (Clockwise)

Preceding gene: 157962119

Following gene: 157962121

Centisome position: 53.94

GC content: 44.74

Gene sequence:

>666_bases
ATGTCTGAAAAAATTACAATTATACTCGTCGATGACCATATATTAGTCCGAGCAGGGATCCGAAGTTTATTAGAGTCCAT
CGCCAATGTTGAAGTCATTCAAGAGTCAGGAGATGGAATTGAAGCCTTGTCGTTACTGCGAGCCCACGAACCGACACTGT
TGATATTAGACATCTCCTTACCCGGCTTGAACGGACTCGAAGTCGCCCGTAGCGTCACAAAGATGAAGACCAAGACAAAA
ATCTTAATGCTGTCGATGCACAGCGACATTGAATACGTTGCAAAAGCACTCACCATAGGCAGCCACGGTTACCTCATGAA
AGAGTCTGCCGTCGACGAACTCGAAACCGCTATTTCTACACTGATGAGTGACAAACAATATATAGGGAAAAACATCGATC
TGCAGATGGTCGATAAACTCAAAGGCGATAGCAATCAAGACAGCGATTTAATAGAACTGCTGACTAGCCGTCAGAGGCAG
ATCTTGCAGCTGATTGCCGAAGGTTATTCAACAAGGGAGATAGCCCTACGCATGAATGTAAGTATTAAAACGGTTGAGAC
CCATCGCGCCCATATTATGTCCCGCCTCAATATATTTGATATTGCCGGTCTCGTGCGGTTTGCCATTCGTTCTAAACTGA
TTTGCCTCAATGAAGAGCCACACTAA

Upstream 100 bases:

>100_bases
GGACTACTCGGTATGGAAGAGCGTGTGCATTCGTTATCTGGAAAATTGATGCTTCACTCAAGTGTCACAAATGGTTCAAT
AATTAAGGTGGTGATCCCTA

Downstream 100 bases:

>100_bases
ATGGTGTGGCCCTGACGCTTAAGTTCGAAATCAATACTCGACGCATCATGGCTTGCGACAAAGCCATTAATAGTGGCAGT
AACAGAATACTGCGACAGAA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSEKITIILVDDHILVRAGIRSLLESIANVEVIQESGDGIEALSLLRAHEPTLLILDISLPGLNGLEVARSVTKMKTKTK
ILMLSMHSDIEYVAKALTIGSHGYLMKESAVDELETAISTLMSDKQYIGKNIDLQMVDKLKGDSNQDSDLIELLTSRQRQ
ILQLIAEGYSTREIALRMNVSIKTVETHRAHIMSRLNIFDIAGLVRFAIRSKLICLNEEPH

Sequences:

>Translated_221_residues
MSEKITIILVDDHILVRAGIRSLLESIANVEVIQESGDGIEALSLLRAHEPTLLILDISLPGLNGLEVARSVTKMKTKTK
ILMLSMHSDIEYVAKALTIGSHGYLMKESAVDELETAISTLMSDKQYIGKNIDLQMVDKLKGDSNQDSDLIELLTSRQRQ
ILQLIAEGYSTREIALRMNVSIKTVETHRAHIMSRLNIFDIAGLVRFAIRSKLICLNEEPH
>Mature_220_residues
SEKITIILVDDHILVRAGIRSLLESIANVEVIQESGDGIEALSLLRAHEPTLLILDISLPGLNGLEVARSVTKMKTKTKI
LMLSMHSDIEYVAKALTIGSHGYLMKESAVDELETAISTLMSDKQYIGKNIDLQMVDKLKGDSNQDSDLIELLTSRQRQI
LQLIAEGYSTREIALRMNVSIKTVETHRAHIMSRLNIFDIAGLVRFAIRSKLICLNEEPH

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=35.8851674641148, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=33.6633663366337, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1786747, Length=209, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=27.1794871794872, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=26.5700483091787, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1788546, Length=209, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24645; Mature: 24514

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKITIILVDDHILVRAGIRSLLESIANVEVIQESGDGIEALSLLRAHEPTLLILDISL
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCCEEEEEEECC
PGLNGLEVARSVTKMKTKTKILMLSMHSDIEYVAKALTIGSHGYLMKESAVDELETAIST
CCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
LMSDKQYIGKNIDLQMVDKLKGDSNQDSDLIELLTSRQRQILQLIAEGYSTREIALRMNV
HHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
SIKTVETHRAHIMSRLNIFDIAGLVRFAIRSKLICLNEEPH
EEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEECCCCC
>Mature Secondary Structure 
SEKITIILVDDHILVRAGIRSLLESIANVEVIQESGDGIEALSLLRAHEPTLLILDISL
CCEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCCEEEEEEECC
PGLNGLEVARSVTKMKTKTKILMLSMHSDIEYVAKALTIGSHGYLMKESAVDELETAIST
CCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
LMSDKQYIGKNIDLQMVDKLKGDSNQDSDLIELLTSRQRQILQLIAEGYSTREIALRMNV
HHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
SIKTVETHRAHIMSRLNIFDIAGLVRFAIRSKLICLNEEPH
EEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]