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The map label for this gene is yjjG [H]

Identifier: 157961677

GI number: 157961677

Start: 2255283

End: 2255975

Strand: Direct

Name: yjjG [H]

Synonym: Spea_1853

Alternate gene names: 157961677

Gene position: 2255283-2255975 (Clockwise)

Preceding gene: 157961676

Following gene: 157961679

Centisome position: 43.58

GC content: 45.17

Gene sequence:

>693_bases
ATGCAGTATAAATGGGTACTTTTTGACGCCGATGAAACCTTGTTTCACTTCGATGCATTTCAAGGGTTACAGCTGATGTT
CTCCCGTTTTGATGTGGATTTTACTCGTCAAGACTTCATGCAATATCAAACGGTTAACCAGCCACTTTGGGTAGACTATC
AAGATGGCAAACTGACCGCCAAAGAACTACAAAATATTCGTTTCGAATCTTGGGCGCAGAAACTGGCAGTTTCAACCCAG
AGGCTTAATAGTGACTTTTTAAAGGCCATGGCGGAGATCTGTCAGTTACTACCCGGGGCACAAGAACTGATTGATAGCCT
TTCTGGTCGGGTCAATATGGGGATCATTACCAATGGCTTTACCGAGTTGCAAACGGTACGACTCGAGAAGGTCGGCTTAG
CTCAGCATTTCTCGCCCCTAGTGATCTCTGAAGAGGTCGGAATGGCTAAGCCAGATATCGGCATTTTTAACCACGCCTTT
GCTATGATGGGCCACCCAGCTAAAGAGTCGGTGTTAATGGTGGGCGATAACCCTCATTCTGATATTCTAGGTGGGTTAAA
TGCTGGTATTCACACCTGCTGGCTTAATAGTCATGGAGCCGAAAAACCCCATGATATCGACCCTCACTATCAGGTGAGTT
CGTTATGCGAATTAAGACTATTACTCACCGATAAGACCATTAATCCGAGTTAA

Upstream 100 bases:

>100_bases
AGATGGTTAATAGCAAAAATGCATCTCAGTCTTGGACAATAAAAAGCACTTAAGATAACCTTGGCCAACTTTTATTGTGG
TAATTTTTAATAGGATTGAG

Downstream 100 bases:

>100_bases
GATGGTGGCTAAATGCTTTAGCTTTTAGCGTTTTTTCTCGAAATGAAGCAAGCGGTTATTGGCAGGCATGGGGTGATCTT
CGATTAACTCCAAGCCTTGC

Product: nucleotidase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MQYKWVLFDADETLFHFDAFQGLQLMFSRFDVDFTRQDFMQYQTVNQPLWVDYQDGKLTAKELQNIRFESWAQKLAVSTQ
RLNSDFLKAMAEICQLLPGAQELIDSLSGRVNMGIITNGFTELQTVRLEKVGLAQHFSPLVISEEVGMAKPDIGIFNHAF
AMMGHPAKESVLMVGDNPHSDILGGLNAGIHTCWLNSHGAEKPHDIDPHYQVSSLCELRLLLTDKTINPS

Sequences:

>Translated_230_residues
MQYKWVLFDADETLFHFDAFQGLQLMFSRFDVDFTRQDFMQYQTVNQPLWVDYQDGKLTAKELQNIRFESWAQKLAVSTQ
RLNSDFLKAMAEICQLLPGAQELIDSLSGRVNMGIITNGFTELQTVRLEKVGLAQHFSPLVISEEVGMAKPDIGIFNHAF
AMMGHPAKESVLMVGDNPHSDILGGLNAGIHTCWLNSHGAEKPHDIDPHYQVSSLCELRLLLTDKTINPS
>Mature_230_residues
MQYKWVLFDADETLFHFDAFQGLQLMFSRFDVDFTRQDFMQYQTVNQPLWVDYQDGKLTAKELQNIRFESWAQKLAVSTQ
RLNSDFLKAMAEICQLLPGAQELIDSLSGRVNMGIITNGFTELQTVRLEKVGLAQHFSPLVISEEVGMAKPDIGIFNHAF
AMMGHPAKESVLMVGDNPHSDILGGLNAGIHTCWLNSHGAEKPHDIDPHYQVSSLCELRLLLTDKTINPS

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=215, Percent_Identity=26.9767441860465, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790833, Length=222, Percent_Identity=56.7567567567568, Blast_Score=266, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25987; Mature: 25987

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYKWVLFDADETLFHFDAFQGLQLMFSRFDVDFTRQDFMQYQTVNQPLWVDYQDGKLTA
CCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCH
KELQNIRFESWAQKLAVSTQRLNSDFLKAMAEICQLLPGAQELIDSLSGRVNMGIITNGF
HHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCH
TELQTVRLEKVGLAQHFSPLVISEEVGMAKPDIGIFNHAFAMMGHPAKESVLMVGDNPHS
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCH
DILGGLNAGIHTCWLNSHGAEKPHDIDPHYQVSSLCELRLLLTDKTINPS
HHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MQYKWVLFDADETLFHFDAFQGLQLMFSRFDVDFTRQDFMQYQTVNQPLWVDYQDGKLTA
CCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCH
KELQNIRFESWAQKLAVSTQRLNSDFLKAMAEICQLLPGAQELIDSLSGRVNMGIITNGF
HHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCH
TELQTVRLEKVGLAQHFSPLVISEEVGMAKPDIGIFNHAFAMMGHPAKESVLMVGDNPHS
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCH
DILGGLNAGIHTCWLNSHGAEKPHDIDPHYQVSSLCELRLLLTDKTINPS
HHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]