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The map label for this gene is oadA [H]

Identifier: 157961027

GI number: 157961027

Start: 1459138

End: 1460949

Strand: Direct

Name: oadA [H]

Synonym: Spea_1199

Alternate gene names: 157961027

Gene position: 1459138-1460949 (Clockwise)

Preceding gene: 157961026

Following gene: 157961028

Centisome position: 28.2

GC content: 47.02

Gene sequence:

>1812_bases
ATGAGCAAGCCATTGGCTTTAACTGATGTTGTCTTAAGAGATGCACACCAATCTATTCTCGCTACTCGTTTGCGTACCGA
AGATATGTTACCTATTGCGCCACTACTGGATAAGGTGGGCCTTTGGTCTATAGAGTCATGGGGCGGTGCCACTTTTGACT
CTTGTATTCGTTATTTAGGTGAAGATCCTTGGGAGAGGATCCGTGAACTCAAGAAGGTTATGCCTAATACACCTCAACAG
ATGTTATTGCGCGGACAAAACCTCCTAGGTTACCGTCACTATGCAGATGACCTAGTACATCGTTTTGTTGAGCGAGCCCA
TACCAATGGTGTCGATGTATTCCGTGTCTTCGATGCGATGAACGATGTGCGCAACCTAGAAACTGCGGTTAAAGCTGTTG
TCGAAGTCGGCGGCCATGCTCAAGGCACACTATCTTATACTACTAGCCCAGTGCATAACTTGACCACTTGGATCTATATG
GCAAAGCGTATCGAAGATATGGGTTGCCATTCTCTGTGTATTAAAGACATGGCTGGGCTATTAAAGCCATTTGAAGCATT
TGAGCTTATTAGCCAAATTAAGTCGCAAACCGATCTGGTTTTATCTCTGCACTGTCATGCCACTACAGGCCTAAGTACGG
CAACCTATCAAAAAGCCATTGAAGCTGGCATCGATGTCCTCGATACGGCTATCTCTTCAATGAGTCAGACCTATGGACAC
AGTGCAACTGAAACCTTGGTTGCTATGGTTGAAGGCACTGATAGAGCAACGGGTTACGATATGGCGTTGCTTGAAGAGAT
CGCGGCTTACTTTAGAATCATACGTAAGAAGTATGCGGCTTTCGAAGGTGAGCTAAAGGGGATCGACTCACGTATCCTGC
GTGCTCAAGTGCCTGGTGGAATGCTGACTAATATGGAAAGCCAGCTCAAAGAGCAGGGCGCCGCTGACAAGTTAGATCTT
GTACTTGAGGAGATCCCTCGAGTACGAGAAGACTTAGGTTTCTTGCCTTTAGTCACGCCAACCTCACAAATCGTTGGTAC
TCAGTCTGTTATCAACGTACTAACAGGTGAGCGTTATAAATCAATGACTAAAGAAACTGAAGGGGTATTAAAAGGTGAAT
ACGGTGCAACACCTGCCCCTGTTAATGCCGAACTTCAGCAGCGTGTATTGGCTGGCAAAGAAGCGATTACCTGCCGCCCG
GCAGACTTGCTTGAGTCTGAATTAGATAAATTGCGCATCGAGTTAAAAGAGAAAGCCGCTGCCGATGGCATAACGCTTGC
TGAAGAGCTCGATGATGACGTTCTGACATACGCATTATTCCCACAGATCGGTCTTAAATTCCTTAGTAATCGTAATAACC
CTGATGTGTTTGAGCCAAAGCCTGAGGTGGCGGCTAAAGCACTGGAGGAAGCTAAGAAGGCTGAGATTGCAGCGGCCAAT
AAGCAAGGGCCAGAAACTTATACTGTTACTGTTCAAGGCCAAAGCTTTGTGGTTGAAGTCGCAGAAGGGGGGGATATCAG
TCAGATCACCCCAAGCGAGAATGTAGTGCCGTTTACTGCACCAGTTCAAGCTGCGCCAGTTGTGGATCTATCTGCAGTTA
AGCATGAGCAGAATGCGCCGCTTTCGGGCAATATCTTTAAAGTACACGTCTCGCCTGGCGATAGCGTCAAAGAGGGGGAT
GTTGTGATCATTCTAGAAGCGATGAAGATGGAAACCGAAGTTCGTGCAGAGGCCGATGGGGTGATCTCAAAGGTTTGGGT
TAAAGAAGGTGACGCTGTCGCAGTGGGTAGTCAATTGTTGGCATTAGCTTAG

Upstream 100 bases:

>100_bases
AATCGAGTCAATCCGCAGTGAGCCCATTAATGGCGGCGGTTATTACTGCTGCAATTCATCAGCACCGTAAAAAAGCATAA
TAAAAGTAGGGAGTTTTTGT

Downstream 100 bases:

>100_bases
GGGTCATCATGGAAGGATTAATCGCGTTTTGGTCTGAATCTGGCATTGCTAACTTTACCTCGGGCCAATTGCTAATGATG
GGCGTGGGTTGCCTGTTGTT

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSKPLALTDVVLRDAHQSILATRLRTEDMLPIAPLLDKVGLWSIESWGGATFDSCIRYLGEDPWERIRELKKVMPNTPQQ
MLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAMNDVRNLETAVKAVVEVGGHAQGTLSYTTSPVHNLTTWIYM
AKRIEDMGCHSLCIKDMAGLLKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
SATETLVAMVEGTDRATGYDMALLEEIAAYFRIIRKKYAAFEGELKGIDSRILRAQVPGGMLTNMESQLKEQGAADKLDL
VLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYKSMTKETEGVLKGEYGATPAPVNAELQQRVLAGKEAITCRP
ADLLESELDKLRIELKEKAAADGITLAEELDDDVLTYALFPQIGLKFLSNRNNPDVFEPKPEVAAKALEEAKKAEIAAAN
KQGPETYTVTVQGQSFVVEVAEGGDISQITPSENVVPFTAPVQAAPVVDLSAVKHEQNAPLSGNIFKVHVSPGDSVKEGD
VVIILEAMKMETEVRAEADGVISKVWVKEGDAVAVGSQLLALA

Sequences:

>Translated_603_residues
MSKPLALTDVVLRDAHQSILATRLRTEDMLPIAPLLDKVGLWSIESWGGATFDSCIRYLGEDPWERIRELKKVMPNTPQQ
MLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAMNDVRNLETAVKAVVEVGGHAQGTLSYTTSPVHNLTTWIYM
AKRIEDMGCHSLCIKDMAGLLKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
SATETLVAMVEGTDRATGYDMALLEEIAAYFRIIRKKYAAFEGELKGIDSRILRAQVPGGMLTNMESQLKEQGAADKLDL
VLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYKSMTKETEGVLKGEYGATPAPVNAELQQRVLAGKEAITCRP
ADLLESELDKLRIELKEKAAADGITLAEELDDDVLTYALFPQIGLKFLSNRNNPDVFEPKPEVAAKALEEAKKAEIAAAN
KQGPETYTVTVQGQSFVVEVAEGGDISQITPSENVVPFTAPVQAAPVVDLSAVKHEQNAPLSGNIFKVHVSPGDSVKEGD
VVIILEAMKMETEVRAEADGVISKVWVKEGDAVAVGSQLLALA
>Mature_602_residues
SKPLALTDVVLRDAHQSILATRLRTEDMLPIAPLLDKVGLWSIESWGGATFDSCIRYLGEDPWERIRELKKVMPNTPQQM
LLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAMNDVRNLETAVKAVVEVGGHAQGTLSYTTSPVHNLTTWIYMA
KRIEDMGCHSLCIKDMAGLLKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGHS
ATETLVAMVEGTDRATGYDMALLEEIAAYFRIIRKKYAAFEGELKGIDSRILRAQVPGGMLTNMESQLKEQGAADKLDLV
LEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYKSMTKETEGVLKGEYGATPAPVNAELQQRVLAGKEAITCRPA
DLLESELDKLRIELKEKAAADGITLAEELDDDVLTYALFPQIGLKFLSNRNNPDVFEPKPEVAAKALEEAKKAEIAAANK
QGPETYTVTVQGQSFVVEVAEGGDISQITPSENVVPFTAPVQAAPVVDLSAVKHEQNAPLSGNIFKVHVSPGDSVKEGDV
VIILEAMKMETEVRAEADGVISKVWVKEGDAVAVGSQLLALA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=635, Percent_Identity=32.4409448818898, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI106049295, Length=635, Percent_Identity=32.4409448818898, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI106049292, Length=635, Percent_Identity=32.4409448818898, Blast_Score=281, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17562816, Length=631, Percent_Identity=31.5372424722662, Blast_Score=302, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6319695, Length=634, Percent_Identity=33.1230283911672, Blast_Score=316, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6321376, Length=634, Percent_Identity=32.9652996845426, Blast_Score=306, Evalue=4e-84,
Organism=Drosophila melanogaster, GI281363050, Length=627, Percent_Identity=33.1738437001595, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652224, Length=627, Percent_Identity=33.1738437001595, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652222, Length=627, Percent_Identity=33.1738437001595, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652220, Length=627, Percent_Identity=33.1738437001595, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652218, Length=627, Percent_Identity=33.1738437001595, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652212, Length=627, Percent_Identity=33.1738437001595, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652210, Length=627, Percent_Identity=33.1738437001595, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652214, Length=627, Percent_Identity=33.1738437001595, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI19921944, Length=627, Percent_Identity=33.1738437001595, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24652216, Length=627, Percent_Identity=33.1738437001595, Blast_Score=302, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 65840; Mature: 65709

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLALTDVVLRDAHQSILATRLRTEDMLPIAPLLDKVGLWSIESWGGATFDSCIRYLG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEECCCCCCCHHHHHHHHC
EDPWERIRELKKVMPNTPQQMLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAM
CCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NDVRNLETAVKAVVEVGGHAQGTLSYTTSPVHNLTTWIYMAKRIEDMGCHSLCIKDMAGL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
HCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATETLVAMVEGTDRATGYDMALLEEIAAYFRIIRKKYAAFEGELKGIDSRILRAQVPGG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHCCCCC
MLTNMESQLKEQGAADKLDLVLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHH
SMTKETEGVLKGEYGATPAPVNAELQQRVLAGKEAITCRPADLLESELDKLRIELKEKAA
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHC
ADGITLAEELDDDVLTYALFPQIGLKFLSNRNNPDVFEPKPEVAAKALEEAKKAEIAAAN
CCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
KQGPETYTVTVQGQSFVVEVAEGGDISQITPSENVVPFTAPVQAAPVVDLSAVKHEQNAP
CCCCCEEEEEEECCEEEEEEECCCCCCEECCCCCEEEECCCCCCCCCCHHHHHHHCCCCC
LSGNIFKVHVSPGDSVKEGDVVIILEAMKMETEVRAEADGVISKVWVKEGDAVAVGSQLL
CCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHH
ALA
HCC
>Mature Secondary Structure 
SKPLALTDVVLRDAHQSILATRLRTEDMLPIAPLLDKVGLWSIESWGGATFDSCIRYLG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEECCCCCCCHHHHHHHHC
EDPWERIRELKKVMPNTPQQMLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAM
CCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NDVRNLETAVKAVVEVGGHAQGTLSYTTSPVHNLTTWIYMAKRIEDMGCHSLCIKDMAGL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
HCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATETLVAMVEGTDRATGYDMALLEEIAAYFRIIRKKYAAFEGELKGIDSRILRAQVPGG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHCCCCC
MLTNMESQLKEQGAADKLDLVLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHH
SMTKETEGVLKGEYGATPAPVNAELQQRVLAGKEAITCRPADLLESELDKLRIELKEKAA
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHC
ADGITLAEELDDDVLTYALFPQIGLKFLSNRNNPDVFEPKPEVAAKALEEAKKAEIAAAN
CCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
KQGPETYTVTVQGQSFVVEVAEGGDISQITPSENVVPFTAPVQAAPVVDLSAVKHEQNAP
CCCCCEEEEEEECCEEEEEEECCCCCCEECCCCCEEEECCCCCCCCCCHHHHHHHCCCCC
LSGNIFKVHVSPGDSVKEGDVVIILEAMKMETEVRAEADGVISKVWVKEGDAVAVGSQLL
CCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHH
ALA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]