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The map label for this gene is acpS

Identifier: 157960869

GI number: 157960869

Start: 1263587

End: 1263982

Strand: Direct

Name: acpS

Synonym: Spea_1041

Alternate gene names: 157960869

Gene position: 1263587-1263982 (Clockwise)

Preceding gene: 157960868

Following gene: 157960872

Centisome position: 24.42

GC content: 48.74

Gene sequence:

>396_bases
ATGATTGTGGGTTTAGGCACTGACATTGTGGAAATAGCTCGAATTGAGTCGCGTATTCCAGCAGCTGGCGATGAGGCGTT
ATTAACTTGCCGTTTAGCTAAGCGTGTATTAACCGAAACAGAGTTTGCACTCTTTGTTGGTTCAACTCAACCTGCTCGCT
ACCTGGCTAAGCGCTTTGCCGCTAAAGAGGCAGCAGCGAAAGCACTGGGTACAGGCATAGGCCGCGGGGTATCTTTTCAG
CATATTGAGATCAGTAATAATGACAATGGTGCACCACAGGTTGTCTTTACTGATGGCGCATCTGAGCGGCTATCTCAGCT
TGGGGGAGTGAAAGCGCATCTCTCTATTGCCGATGAGCAGCACTATGCGACAGCGACGGTTATATTGGAGTCTTAA

Upstream 100 bases:

>100_bases
AACTTAGCATAGCGTTGTTATTGAAGCCGAGACTGATGCTCTCGGCTTTTATTTATCCCTTATGGGGCTAAGTTTAAGCG
GTATGAGGTAGAGAGTCGTT

Downstream 100 bases:

>100_bases
TTTATCAAGACATTTAAAAAGAGGCTTTAGTGTTAAACACATCGAGGCTACAGTTCATGACATGTTCGCCTTCGCAAACT
CGCTCGTCGGTGAATTTGAA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MIVGLGTDIVEIARIESRIPAAGDEALLTCRLAKRVLTETEFALFVGSTQPARYLAKRFAAKEAAAKALGTGIGRGVSFQ
HIEISNNDNGAPQVVFTDGASERLSQLGGVKAHLSIADEQHYATATVILES

Sequences:

>Translated_131_residues
MIVGLGTDIVEIARIESRIPAAGDEALLTCRLAKRVLTETEFALFVGSTQPARYLAKRFAAKEAAAKALGTGIGRGVSFQ
HIEISNNDNGAPQVVFTDGASERLSQLGGVKAHLSIADEQHYATATVILES
>Mature_131_residues
MIVGLGTDIVEIARIESRIPAAGDEALLTCRLAKRVLTETEFALFVGSTQPARYLAKRFAAKEAAAKALGTGIGRGVSFQ
HIEISNNDNGAPQVVFTDGASERLSQLGGVKAHLSIADEQHYATATVILES

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=130, Percent_Identity=51.5384615384615, Blast_Score=130, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SHEPA (A8H1D1)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001500903.1
- ProteinModelPortal:   A8H1D1
- SMR:   A8H1D1
- STRING:   A8H1D1
- GeneID:   5661440
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_1041
- NMPDR:   fig|398579.3.peg.907
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   SPEA398579:SPEA_1041-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13852; Mature: 13852

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLGTDIVEIARIESRIPAAGDEALLTCRLAKRVLTETEFALFVGSTQPARYLAKRFA
CEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
AKEAAAKALGTGIGRGVSFQHIEISNNDNGAPQVVFTDGASERLSQLGGVKAHLSIADEQ
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCC
HYATATVILES
CEEEEEEEEEC
>Mature Secondary Structure
MIVGLGTDIVEIARIESRIPAAGDEALLTCRLAKRVLTETEFALFVGSTQPARYLAKRFA
CEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
AKEAAAKALGTGIGRGVSFQHIEISNNDNGAPQVVFTDGASERLSQLGGVKAHLSIADEQ
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHHCCCEEEEEECCCC
HYATATVILES
CEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA