Click here to switch to the map view.

The map label for this gene is gluQ [H]

Identifier: 157960525

GI number: 157960525

Start: 857471

End: 858349

Strand: Reverse

Name: gluQ [H]

Synonym: Spea_0697

Alternate gene names: 157960525

Gene position: 858349-857471 (Counterclockwise)

Preceding gene: 157960526

Following gene: 157960524

Centisome position: 16.59

GC content: 47.21

Gene sequence:

>879_bases
ATGGTTAATACGACTCCCTATATAGGCCGCTTTGCGCCTTCCCCATCTGGTCCTCTTCATTTTGGTTCATTGATTGCTGC
CCTCGGCAGTTTTTTGCGTGCCCGCTCTTTGGGCGGCAAATGGTTGGTTCGTATCGAAGATATCGATCCGCCACGTGAAA
TTGCTGGCGCCAGCAGTGCCATTTTGAAAACCCTTGAAGCCTACGGCTTAGAGTGGGATGAGTCTGTGCTCTATCAGAGC
CAACGACTCGACGTATATCAAGCTAGAATTGAGCAATTACTGCAAGATAATCAAGCCTATTATTGTCAATGTACGCGCAA
GCAGATCCAAGCCATGGGCGGCAGTTACGATGGCCGTTGCGGTCAGTTATTACAGCCACTCAACCAAGGGGCTATTCGAG
TCCGCAATCCATTTGCGGTCGAGCATTTTGTCGATCAACATATGGGACATGTGTCTGTTGATAGCGCATTCGCAGCAGAG
GACTTTATCATCAAGCGCAGCGATGGCTTATATGCTTATCAGCTGGCGGTAGTACTGGATGATATTTTCCAGCAAATTAC
CGAAGTCGTCAGAGGGTGCGATCTACTTGAACCAACGTGTCGTCAAGAAAGCTTGTATCAGATCCTAAAAGCGCCTACAC
CACAGTGGTTACATCTGCCGTTAGCCTGTGCCGAAAAAGGTAGAAAGTTATCTAAGCAAAACCATGCACCAGCAATTGAT
AATCTGTACCCACAAGCCAGTATTAATGCCGCTTTAGTCTTCCTAGGTCAACAGCCTGTGACAGCAGAGTCTCAGGTCAG
TAAGATGATTGAACAAGCCGTGAGTCAATTTGATCTCTCAAAGGTACCTAAACAATCGGAAATACTCCTTGATACGTGA

Upstream 100 bases:

>100_bases
AAAACGTTAGCTGAGATCAAAGAAAAGCAGATGGCAGGCTAAATGCCATCTTAAGGTGCGGAGCTTATGGCTCCGCTCTT
TTGTTTTACGACTGCTATAA

Downstream 100 bases:

>100_bases
GCTCAATCGTATACTCATTAAGCTTTAATTGAGTTATCATAGCCCACTTGTTTTAACCAAATTAAGATCCAAATCAGAGG
TGTCCCATTTTTCGCCGTAT

Product: glutamyl-tRNA synthetase class Ic

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MVNTTPYIGRFAPSPSGPLHFGSLIAALGSFLRARSLGGKWLVRIEDIDPPREIAGASSAILKTLEAYGLEWDESVLYQS
QRLDVYQARIEQLLQDNQAYYCQCTRKQIQAMGGSYDGRCGQLLQPLNQGAIRVRNPFAVEHFVDQHMGHVSVDSAFAAE
DFIIKRSDGLYAYQLAVVLDDIFQQITEVVRGCDLLEPTCRQESLYQILKAPTPQWLHLPLACAEKGRKLSKQNHAPAID
NLYPQASINAALVFLGQQPVTAESQVSKMIEQAVSQFDLSKVPKQSEILLDT

Sequences:

>Translated_292_residues
MVNTTPYIGRFAPSPSGPLHFGSLIAALGSFLRARSLGGKWLVRIEDIDPPREIAGASSAILKTLEAYGLEWDESVLYQS
QRLDVYQARIEQLLQDNQAYYCQCTRKQIQAMGGSYDGRCGQLLQPLNQGAIRVRNPFAVEHFVDQHMGHVSVDSAFAAE
DFIIKRSDGLYAYQLAVVLDDIFQQITEVVRGCDLLEPTCRQESLYQILKAPTPQWLHLPLACAEKGRKLSKQNHAPAID
NLYPQASINAALVFLGQQPVTAESQVSKMIEQAVSQFDLSKVPKQSEILLDT
>Mature_292_residues
MVNTTPYIGRFAPSPSGPLHFGSLIAALGSFLRARSLGGKWLVRIEDIDPPREIAGASSAILKTLEAYGLEWDESVLYQS
QRLDVYQARIEQLLQDNQAYYCQCTRKQIQAMGGSYDGRCGQLLQPLNQGAIRVRNPFAVEHFVDQHMGHVSVDSAFAAE
DFIIKRSDGLYAYQLAVVLDDIFQQITEVVRGCDLLEPTCRQESLYQILKAPTPQWLHLPLACAEKGRKLSKQNHAPAID
NLYPQASINAALVFLGQQPVTAESQVSKMIEQAVSQFDLSKVPKQSEILLDT

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=310, Percent_Identity=32.258064516129, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI226510925, Length=287, Percent_Identity=53.3101045296167, Blast_Score=304, Evalue=3e-84,
Organism=Escherichia coli, GI1788743, Length=290, Percent_Identity=36.2068965517241, Blast_Score=160, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71993394, Length=315, Percent_Identity=30.1587301587302, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324540, Length=314, Percent_Identity=30.8917197452229, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24665321, Length=306, Percent_Identity=32.0261437908497, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 32464; Mature: 32464

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTTPYIGRFAPSPSGPLHFGSLIAALGSFLRARSLGGKWLVRIEDIDPPREIAGASSA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCHHHH
ILKTLEAYGLEWDESVLYQSQRLDVYQARIEQLLQDNQAYYCQCTRKQIQAMGGSYDGRC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCH
GQLLQPLNQGAIRVRNPFAVEHFVDQHMGHVSVDSAFAAEDFIIKRSDGLYAYQLAVVLD
HHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHEEECCCCCHHHHHHHHHH
DIFQQITEVVRGCDLLEPTCRQESLYQILKAPTPQWLHLPLACAEKGRKLSKQNHAPAID
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEECHHHHHHHCHHHHHCCCCCCHH
NLYPQASINAALVFLGQQPVTAESQVSKMIEQAVSQFDLSKVPKQSEILLDT
HCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure
MVNTTPYIGRFAPSPSGPLHFGSLIAALGSFLRARSLGGKWLVRIEDIDPPREIAGASSA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCHHHH
ILKTLEAYGLEWDESVLYQSQRLDVYQARIEQLLQDNQAYYCQCTRKQIQAMGGSYDGRC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCH
GQLLQPLNQGAIRVRNPFAVEHFVDQHMGHVSVDSAFAAEDFIIKRSDGLYAYQLAVVLD
HHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHEEECCCCCHHHHHHHHHH
DIFQQITEVVRGCDLLEPTCRQESLYQILKAPTPQWLHLPLACAEKGRKLSKQNHAPAID
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEECHHHHHHHCHHHHHCCCCCCHH
NLYPQASINAALVFLGQQPVTAESQVSKMIEQAVSQFDLSKVPKQSEILLDT
HCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]