Click here to switch to the map view.

The map label for this gene is dnaB [H]

Identifier: 157825863

GI number: 157825863

Start: 720179

End: 721663

Strand: Direct

Name: dnaB [H]

Synonym: A1C_04010

Alternate gene names: 157825863

Gene position: 720179-721663 (Clockwise)

Preceding gene: 157825862

Following gene: 157825866

Centisome position: 58.5

GC content: 33.2

Gene sequence:

>1485_bases
ATGGCACATAATAAAATAAATAACGACACAAATATACTAACTGATGATGAAGATAATTTACCCATACCAAGGGTTTTACC
TTCAAATGTTCAAGCGGAGCAAATGCTACTTGGTGCGATTTTAACCAATAATGAATTACTAAATTACGTATCGGAATTTT
TACGTGATGAACATTTTTTTGAACCTATTCATCAAAAAATATATAACGCAATTGAAAAAATTACCGAAAAAGGTTTGATA
GCTACACCTATTACTTTACGTAGCATGTTAACTCAAGATAAACTATTTCAAGCAATAGAAGGATCGGAGTATTTAGCAAA
ATTGATAACTATGTCAATGATGGTAATAAATCCGCTTGATTACGGTAAAATAATATATGATTTAGCAATAAAGCGTAATT
TAATAAATATCGGTGAAGAAGTAGTAAATAATGCCTATAATTCTTCATTAGAAGTTGAAGCAAAGGCACAGATTGAATAT
GCCGAAGCTAAACTTTACGATTTAGCTAGCGAAGGCTTGAATGAAAAAAGTTTTACCAAAATCGGTATATCTATTTCAGA
GTCACTAGCTAGTATTAATAGGGCCATGAAAAATAATGATCACGTAATCGGTATATCTACCGGTTTGCTTGATCTAGATA
ATAAATTATTCGGCTTTCATAATTCCGATCTTATCATTCTTGCAGGACGTCCGTCGATGGGTAAAACGGCATTTGCTATA
AATCTTGCACTTAACGCCTGTAATAATATGCGTCGTAAAAATATTATGGATAATCAAGAAATTCAGTCGGTAGGTTTTTT
CTCGTTAGAAATGTCCTCAGAACAGCTAACCACACGTCTACTTTCAATGTGTGCAGAAATTGATTCTACTTCTCTTCGTA
CAGGGATTCTAGGTGAAGAAAAATATAACCGTCTTCGCAAAGAAGCAAATACTTTATCGGAATTACAATTTTTTATCGAT
GATACCCCTGCTCTATCTATTTCCGCTATAAGAACAAGAGCTAGAAGAATGAAACGCAAGCATAATCTTGGTATATTATT
TATCGATTATCTACAATTAATTAGAGGAGCGACTAAATTCGAAAATAGAGTTAGCGAAATTTCAGAGATTACACAAGGTT
TAAAAGCGATAGCAAAAGAGTTAAATATTCCGGTGATCGCCTTATCTCAGCTTTCAAGAGCGGTAGAACTGCGTGAGGAC
AAAAAACCTATGCTATCTGACCTTAGAGAATCAGGAACTATAGAACAGGATGCGGATATAGTAATGTTTATTTACCGTGA
AGAATATTATTTAACTAGAAAAGAACCGGCAGCAGGTGATGCTAAACATGCCGAATGGTTAGATAAGCTCAATAAAGTAT
ATAATATTGCCGATATAATTGTTGCAAAACATCGTAATGGACCGGTTGGAAATGTTCCGCTTTATTATGATAGTCAATTT
TCTAAATTTGGTAATTTGGAGAAAAGAACTTTTAATTCTGTTTAA

Upstream 100 bases:

>100_bases
AAAAATACTAACATTGTTAGTATTTTTAACTGGGTCCTGTGAATAAATCACGTGATGACACTGTATACTTTGCACACCCC
AATAAACTTTAACAAACAAA

Downstream 100 bases:

>100_bases
ATCAGAATTGCCTTAACGTCATTGCGAACGACTAAAGGCGTTGTTGCATGGGTCGATCCCGCTGAGGCTGGAATCCGTCG
TTGTCATACCGTGACTTAAT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MAHNKINNDTNILTDDEDNLPIPRVLPSNVQAEQMLLGAILTNNELLNYVSEFLRDEHFFEPIHQKIYNAIEKITEKGLI
ATPITLRSMLTQDKLFQAIEGSEYLAKLITMSMMVINPLDYGKIIYDLAIKRNLINIGEEVVNNAYNSSLEVEAKAQIEY
AEAKLYDLASEGLNEKSFTKIGISISESLASINRAMKNNDHVIGISTGLLDLDNKLFGFHNSDLIILAGRPSMGKTAFAI
NLALNACNNMRRKNIMDNQEIQSVGFFSLEMSSEQLTTRLLSMCAEIDSTSLRTGILGEEKYNRLRKEANTLSELQFFID
DTPALSISAIRTRARRMKRKHNLGILFIDYLQLIRGATKFENRVSEISEITQGLKAIAKELNIPVIALSQLSRAVELRED
KKPMLSDLRESGTIEQDADIVMFIYREEYYLTRKEPAAGDAKHAEWLDKLNKVYNIADIIVAKHRNGPVGNVPLYYDSQF
SKFGNLEKRTFNSV

Sequences:

>Translated_494_residues
MAHNKINNDTNILTDDEDNLPIPRVLPSNVQAEQMLLGAILTNNELLNYVSEFLRDEHFFEPIHQKIYNAIEKITEKGLI
ATPITLRSMLTQDKLFQAIEGSEYLAKLITMSMMVINPLDYGKIIYDLAIKRNLINIGEEVVNNAYNSSLEVEAKAQIEY
AEAKLYDLASEGLNEKSFTKIGISISESLASINRAMKNNDHVIGISTGLLDLDNKLFGFHNSDLIILAGRPSMGKTAFAI
NLALNACNNMRRKNIMDNQEIQSVGFFSLEMSSEQLTTRLLSMCAEIDSTSLRTGILGEEKYNRLRKEANTLSELQFFID
DTPALSISAIRTRARRMKRKHNLGILFIDYLQLIRGATKFENRVSEISEITQGLKAIAKELNIPVIALSQLSRAVELRED
KKPMLSDLRESGTIEQDADIVMFIYREEYYLTRKEPAAGDAKHAEWLDKLNKVYNIADIIVAKHRNGPVGNVPLYYDSQF
SKFGNLEKRTFNSV
>Mature_493_residues
AHNKINNDTNILTDDEDNLPIPRVLPSNVQAEQMLLGAILTNNELLNYVSEFLRDEHFFEPIHQKIYNAIEKITEKGLIA
TPITLRSMLTQDKLFQAIEGSEYLAKLITMSMMVINPLDYGKIIYDLAIKRNLINIGEEVVNNAYNSSLEVEAKAQIEYA
EAKLYDLASEGLNEKSFTKIGISISESLASINRAMKNNDHVIGISTGLLDLDNKLFGFHNSDLIILAGRPSMGKTAFAIN
LALNACNNMRRKNIMDNQEIQSVGFFSLEMSSEQLTTRLLSMCAEIDSTSLRTGILGEEKYNRLRKEANTLSELQFFIDD
TPALSISAIRTRARRMKRKHNLGILFIDYLQLIRGATKFENRVSEISEITQGLKAIAKELNIPVIALSQLSRAVELREDK
KPMLSDLRESGTIEQDADIVMFIYREEYYLTRKEPAAGDAKHAEWLDKLNKVYNIADIIVAKHRNGPVGNVPLYYDSQFS
KFGNLEKRTFNSV

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=466, Percent_Identity=36.6952789699571, Blast_Score=294, Evalue=8e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 55856; Mature: 55725

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHNKINNDTNILTDDEDNLPIPRVLPSNVQAEQMLLGAILTNNELLNYVSEFLRDEHFF
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EPIHQKIYNAIEKITEKGLIATPITLRSMLTQDKLFQAIEGSEYLAKLITMSMMVINPLD
HHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
YGKIIYDLAIKRNLINIGEEVVNNAYNSSLEVEAKAQIEYAEAKLYDLASEGLNEKSFTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHE
IGISISESLASINRAMKNNDHVIGISTGLLDLDNKLFGFHNSDLIILAGRPSMGKTAFAI
ECHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCCCCCCEEEEECCCCCCCCEEEE
NLALNACNNMRRKNIMDNQEIQSVGFFSLEMSSEQLTTRLLSMCAEIDSTSLRTGILGEE
HHHHHHHHHHHHHCCCCCHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHCCCCHH
KYNRLRKEANTLSELQFFIDDTPALSISAIRTRARRMKRKHNLGILFIDYLQLIRGATKF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCHHHH
ENRVSEISEITQGLKAIAKELNIPVIALSQLSRAVELREDKKPMLSDLRESGTIEQDADI
HHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCE
VMFIYREEYYLTRKEPAAGDAKHAEWLDKLNKVYNIADIIVAKHRNGPVGNVPLYYDSQF
EEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEECCHH
SKFGNLEKRTFNSV
HHHCCCHHHHCCCC
>Mature Secondary Structure 
AHNKINNDTNILTDDEDNLPIPRVLPSNVQAEQMLLGAILTNNELLNYVSEFLRDEHFF
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EPIHQKIYNAIEKITEKGLIATPITLRSMLTQDKLFQAIEGSEYLAKLITMSMMVINPLD
HHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
YGKIIYDLAIKRNLINIGEEVVNNAYNSSLEVEAKAQIEYAEAKLYDLASEGLNEKSFTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHE
IGISISESLASINRAMKNNDHVIGISTGLLDLDNKLFGFHNSDLIILAGRPSMGKTAFAI
ECHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCCCCCCEEEEECCCCCCCCEEEE
NLALNACNNMRRKNIMDNQEIQSVGFFSLEMSSEQLTTRLLSMCAEIDSTSLRTGILGEE
HHHHHHHHHHHHHCCCCCHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHCCCCHH
KYNRLRKEANTLSELQFFIDDTPALSISAIRTRARRMKRKHNLGILFIDYLQLIRGATKF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCHHHH
ENRVSEISEITQGLKAIAKELNIPVIALSQLSRAVELREDKKPMLSDLRESGTIEQDADI
HHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCE
VMFIYREEYYLTRKEPAAGDAKHAEWLDKLNKVYNIADIIVAKHRNGPVGNVPLYYDSQF
EEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEECCHH
SKFGNLEKRTFNSV
HHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA