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The map label for this gene is trxB [H]

Identifier: 157825741

GI number: 157825741

Start: 603763

End: 604695

Strand: Direct

Name: trxB [H]

Synonym: A1C_03335

Alternate gene names: 157825741

Gene position: 603763-604695 (Clockwise)

Preceding gene: 157825740

Following gene: 157825742

Centisome position: 49.04

GC content: 38.05

Gene sequence:

>933_bases
ATGAAAATTACTACTAAAGTACTAATAATAGGCTCAGGTCCTGCTGGTCTAAGTGCCGCTATTTATACGGCTAGAGCCGC
TCTAAAACCAATATTAATTAATGGTATGCGGCCAGGTGGGCAGCTTACAATTACCACCAATGTTGAGAATTATCCAGGAT
TTGTGGAAACGGTGCAAGGACCTTGGCTTATGGAGCAGATGTCTATGCAGGCTCAAAATGTCGGTACAGAAATTATTAGT
GATTATGTGGAAAAAGTGGATTTATCAAAGAGGCCTTTTAAAGTATTTACAGGATCAGGAAATGAATATGAAGCAGAAAG
TATAATCATCTGTACTGGTGCGGAAGCAAAATGGCTTGGTATAGCTTCGGAGCAAGACTTTATGGGGTTTGGTGTTTCGG
CATGTGCTACTTGCGATGGTTTCTTTTTTAAGAATCAAGAAATAGTTGTAGTAGGGGGAGGGAATAGTGCAGTAGAAGAA
GCTTTATACTTAACCAATCATGCTAGCAAAGTTACTATAGTGCATAGGAGAGATAGTTTTAGAGCTGAGCAAATATTACA
AGATCGATTATTTAAAAATCCTAAAATATCGGTAATTTGGGATCATGTAGTAGATGAGATTGTAGGTCGCAATAAGCCAA
AATCTGTTACCGGAGTTAAAATTCAAAATGTCCACACCAAAGAGATTAGTTTATTGAATTGTAGCGGTGTATTTATAGCT
ATCGGGCATGTACCGAATACGGGGTTATTTACTGGACAAATTGCAATGGATGATGATAATTATATCATCACGGAATCAGG
TACAACCAAAACTAATGTAGAAGGTGTTTTTGCTGCCGGTGACGTTCAGGATAAAATTTATAGACAAGCAGTAACTGCTG
CAGGAACAGGCTGTATGGCAGCTCTTGAGGCTGAAAAATTTTTGAATAAATAA

Upstream 100 bases:

>100_bases
TTTTTGAAATTAAAAGCTCGATTTATCTTGCTTTATGCTGTATTCCAGCCCACGCCGGAATGACACAGAGATCATTTAAA
TTAATTAACAAATAATAATT

Downstream 100 bases:

>100_bases
TACATTTCCTAAAAAAAGACATAATCATATAATAATTTATTAATTTAAATTCTTGTATTGAAAATTATAGCAATATACTC
TTTCTTTCTAATGTTCTAAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMRPGGQLTITTNVENYPGFVETVQGPWLMEQMSMQAQNVGTEIIS
DYVEKVDLSKRPFKVFTGSGNEYEAESIIICTGAEAKWLGIASEQDFMGFGVSACATCDGFFFKNQEIVVVGGGNSAVEE
ALYLTNHASKVTIVHRRDSFRAEQILQDRLFKNPKISVIWDHVVDEIVGRNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
IGHVPNTGLFTGQIAMDDDNYIITESGTTKTNVEGVFAAGDVQDKIYRQAVTAAGTGCMAALEAEKFLNK

Sequences:

>Translated_310_residues
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMRPGGQLTITTNVENYPGFVETVQGPWLMEQMSMQAQNVGTEIIS
DYVEKVDLSKRPFKVFTGSGNEYEAESIIICTGAEAKWLGIASEQDFMGFGVSACATCDGFFFKNQEIVVVGGGNSAVEE
ALYLTNHASKVTIVHRRDSFRAEQILQDRLFKNPKISVIWDHVVDEIVGRNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
IGHVPNTGLFTGQIAMDDDNYIITESGTTKTNVEGVFAAGDVQDKIYRQAVTAAGTGCMAALEAEKFLNK
>Mature_310_residues
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMRPGGQLTITTNVENYPGFVETVQGPWLMEQMSMQAQNVGTEIIS
DYVEKVDLSKRPFKVFTGSGNEYEAESIIICTGAEAKWLGIASEQDFMGFGVSACATCDGFFFKNQEIVVVGGGNSAVEE
ALYLTNHASKVTIVHRRDSFRAEQILQDRLFKNPKISVIWDHVVDEIVGRNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
IGHVPNTGLFTGQIAMDDDNYIITESGTTKTNVEGVFAAGDVQDKIYRQAVTAAGTGCMAALEAEKFLNK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=52.7156549520767, Blast_Score=331, Evalue=3e-92,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=33.6601307189542, Blast_Score=138, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=47.4683544303797, Blast_Score=281, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=47.3186119873817, Blast_Score=278, Evalue=6e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33507; Mature: 33507

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMRPGGQLTITTNVENYPGFVETVQG
CCEEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCEEEEEECCCCCCCHHEECCC
PWLMEQMSMQAQNVGTEIISDYVEKVDLSKRPFKVFTGSGNEYEAESIIICTGAEAKWLG
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCEECCEEEEEECCCCEEEE
IASEQDFMGFGVSACATCDGFFFKNQEIVVVGGGNSAVEEALYLTNHASKVTIVHRRDSF
ECCCCCCCCCCCHHHHCCCCEEECCCEEEEEECCCHHHHHHHHEECCCCEEEEEEECCCH
RAEQILQDRLFKNPKISVIWDHVVDEIVGRNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
HHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEECEEECEEEEEECCCEEEE
IGHVPNTGLFTGQIAMDDDNYIITESGTTKTNVEGVFAAGDVQDKIYRQAVTAAGTGCMA
EECCCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHH
ALEAEKFLNK
HHHHHHHHCC
>Mature Secondary Structure
MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMRPGGQLTITTNVENYPGFVETVQG
CCEEEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCEEEEEECCCCCCCHHEECCC
PWLMEQMSMQAQNVGTEIISDYVEKVDLSKRPFKVFTGSGNEYEAESIIICTGAEAKWLG
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCEECCEEEEEECCCCEEEE
IASEQDFMGFGVSACATCDGFFFKNQEIVVVGGGNSAVEEALYLTNHASKVTIVHRRDSF
ECCCCCCCCCCCHHHHCCCCEEECCCEEEEEECCCHHHHHHHHEECCCCEEEEEEECCCH
RAEQILQDRLFKNPKISVIWDHVVDEIVGRNKPKSVTGVKIQNVHTKEISLLNCSGVFIA
HHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEECEEECEEEEEECCCEEEE
IGHVPNTGLFTGQIAMDDDNYIITESGTTKTNVEGVFAAGDVQDKIYRQAVTAAGTGCMA
EECCCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHH
ALEAEKFLNK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]