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The map label for this gene is gpsA

Identifier: 157825736

GI number: 157825736

Start: 599827

End: 600780

Strand: Direct

Name: gpsA

Synonym: A1C_03310

Alternate gene names: 157825736

Gene position: 599827-600780 (Clockwise)

Preceding gene: 157825735

Following gene: 157825737

Centisome position: 48.72

GC content: 32.7

Gene sequence:

>954_bases
ATGAATAAATTTAAAAATATTGCTGTTTATGGCGGAGGGAGTTTCGGTACTAGTCTTGCTGCTTTAGCAGCACAAAACTG
TAGTAATGTTACTTTATTTTTACGTGACGAGGAAATAGCAAAAGAAATTTTACATAAAAAAACTAACATAAAATATTTAG
GTGGTATTAAATTACCTGCTCATTTACATGCTACTACAAACTTAAGTGTAATTAAGGATTTTGAGCTAATTATTATTGCA
GTGCCGTCTTATGCTTTTGATGACTCAATAAAATTATTAAAAACTCACGGCATTTCTGAAGATAATACTCTTCTAATCGC
AACAAAAGGCTTTGCCCGTAATCCTACTGAACTATTTTCTGATAGATTAAAAACTCTATTACCGCATAGCTCTACAGCGT
TTTTTGCAGGTCCGAATTTAGCAAAAGAACTCGCTAAGAATTTACCGGCTTCGGCAAGTATTGCAAGTTTAGATATAGAT
ATAGCAAATAAAATAGCCAATAACATAAGTTCAAAAATTTTTACTACTAATATGACAAGCGATATTGTAACATTACAGGT
AGCAGGAGCGTTGAAAAATATTTTTGCTATTAAAAGTGGAATTGATTTAGCAAGTGAGCAGGGCGAGAATGCAAGGGCAA
CGCTTATAGTGGATGCCTTAAAAGAAATTATTACTTTATCTAAGGTCTTTGGAGGTTTGCAAAAAAATTCTGATATTTTG
CTAGAGGCAGGAGTAGTAGGCGATTTAGTGCTTACTTGTTACGCTTTAGGTTCACGTAATACAAATTTTGGTTATGAGCT
TGGAATTAGTAGTGATAAAAAGAAATTTTTACAGGAATATAAACAGCTAGTAGAGGGAAGAGAAGCATTAAAATTAGTTT
TAGATTTGATAAAGCAATATGATTTACATATGCCTATAATTTCAGAAGTGGCTAGCTATGTCATGCCTGCATAG

Upstream 100 bases:

>100_bases
GATGTAATTCTTCTCGCAATGGTAGAAAACTGGTCTACAAAGGCAACGCCACGTAGGAATGATACAAACATAAACTTGCA
AGCGACAAAGAAAAAATCAA

Downstream 100 bases:

>100_bases
GTGTGGCGTTGTTGCATGGAACGCAAAACCTACTTTATGTCATTCCAGCCTACGCGGGAATGACATAAAATGATCCATGC
AACAACGCTTCCTAGCAATG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNKFKNIAVYGGGSFGTSLAALAAQNCSNVTLFLRDEEIAKEILHKKTNIKYLGGIKLPAHLHATTNLSVIKDFELIIIA
VPSYAFDDSIKLLKTHGISEDNTLLIATKGFARNPTELFSDRLKTLLPHSSTAFFAGPNLAKELAKNLPASASIASLDID
IANKIANNISSKIFTTNMTSDIVTLQVAGALKNIFAIKSGIDLASEQGENARATLIVDALKEIITLSKVFGGLQKNSDIL
LEAGVVGDLVLTCYALGSRNTNFGYELGISSDKKKFLQEYKQLVEGREALKLVLDLIKQYDLHMPIISEVASYVMPA

Sequences:

>Translated_317_residues
MNKFKNIAVYGGGSFGTSLAALAAQNCSNVTLFLRDEEIAKEILHKKTNIKYLGGIKLPAHLHATTNLSVIKDFELIIIA
VPSYAFDDSIKLLKTHGISEDNTLLIATKGFARNPTELFSDRLKTLLPHSSTAFFAGPNLAKELAKNLPASASIASLDID
IANKIANNISSKIFTTNMTSDIVTLQVAGALKNIFAIKSGIDLASEQGENARATLIVDALKEIITLSKVFGGLQKNSDIL
LEAGVVGDLVLTCYALGSRNTNFGYELGISSDKKKFLQEYKQLVEGREALKLVLDLIKQYDLHMPIISEVASYVMPA
>Mature_317_residues
MNKFKNIAVYGGGSFGTSLAALAAQNCSNVTLFLRDEEIAKEILHKKTNIKYLGGIKLPAHLHATTNLSVIKDFELIIIA
VPSYAFDDSIKLLKTHGISEDNTLLIATKGFARNPTELFSDRLKTLLPHSSTAFFAGPNLAKELAKNLPASASIASLDID
IANKIANNISSKIFTTNMTSDIVTLQVAGALKNIFAIKSGIDLASEQGENARATLIVDALKEIITLSKVFGGLQKNSDIL
LEAGVVGDLVLTCYALGSRNTNFGYELGISSDKKKFLQEYKQLVEGREALKLVLDLIKQYDLHMPIISEVASYVMPA

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=275, Percent_Identity=26.9090909090909, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI24307999, Length=269, Percent_Identity=26.3940520446097, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790037, Length=308, Percent_Identity=31.4935064935065, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17507425, Length=314, Percent_Identity=25.1592356687898, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320181, Length=312, Percent_Identity=26.9230769230769, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324513, Length=312, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17136204, Length=276, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17136200, Length=276, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17136202, Length=276, Percent_Identity=28.2608695652174, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_RICAH (A8GNH3)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493456.1
- ProteinModelPortal:   A8GNH3
- SMR:   A8GNH3
- STRING:   A8GNH3
- GeneID:   5644702
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_03310
- NMPDR:   fig|293614.3.peg.618
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- BioCyc:   RAKA293614:A1C_03310-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34304; Mature: 34304

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 109-109 BINDING 109-109 BINDING 141-141 BINDING 259-259 BINDING 285-285

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFKNIAVYGGGSFGTSLAALAAQNCSNVTLFLRDEEIAKEILHKKTNIKYLGGIKLPA
CCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCEEECCCCCCC
HLHATTNLSVIKDFELIIIAVPSYAFDDSIKLLKTHGISEDNTLLIATKGFARNPTELFS
EEEECCCCEEEECCEEEEEEECCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
DRLKTLLPHSSTAFFAGPNLAKELAKNLPASASIASLDIDIANKIANNISSKIFTTNMTS
HHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCEEEECCCC
DIVTLQVAGALKNIFAIKSGIDLASEQGENARATLIVDALKEIITLSKVFGGLQKNSDIL
CEEEEEHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LEAGVVGDLVLTCYALGSRNTNFGYELGISSDKKKFLQEYKQLVEGREALKLVLDLIKQY
EECCHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLHMPIISEVASYVMPA
CCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNKFKNIAVYGGGSFGTSLAALAAQNCSNVTLFLRDEEIAKEILHKKTNIKYLGGIKLPA
CCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCEEECCCCCCC
HLHATTNLSVIKDFELIIIAVPSYAFDDSIKLLKTHGISEDNTLLIATKGFARNPTELFS
EEEECCCCEEEECCEEEEEEECCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
DRLKTLLPHSSTAFFAGPNLAKELAKNLPASASIASLDIDIANKIANNISSKIFTTNMTS
HHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCEEEECCCC
DIVTLQVAGALKNIFAIKSGIDLASEQGENARATLIVDALKEIITLSKVFGGLQKNSDIL
CEEEEEHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LEAGVVGDLVLTCYALGSRNTNFGYELGISSDKKKFLQEYKQLVEGREALKLVLDLIKQY
EECCHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLHMPIISEVASYVMPA
CCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA