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The map label for this gene is ppnK [H]

Identifier: 157825733

GI number: 157825733

Start: 597001

End: 597768

Strand: Reverse

Name: ppnK [H]

Synonym: A1C_03295

Alternate gene names: 157825733

Gene position: 597768-597001 (Counterclockwise)

Preceding gene: 157825738

Following gene: 157825732

Centisome position: 48.56

GC content: 33.33

Gene sequence:

>768_bases
ATGAATATAAATAAAATAGCATTAATTTATAACCAAAATTCCAAACATCTAGCTATTATAGAGGAAATAAAAAAACTCTA
TAATTATTGTAAAATAGAGGAAGCAGAAGCAATTATCGTAATAGGAGGTGATGGAGCATTACTACATAATATTCACCGCT
ATATGCATCTTAATATACCTTTTTATGGAGTTAATTTAGGAAACCTCGGCTTTTTAATGAATCCTTTAGATACTAAGAAT
TTATCACAAAATATACATGAAAGTACTGTTTCTATTCTAAATCCTCTTCTTATGCAAGCTGAAGATATAAGTGGTCAAAT
ATATACCGCACTTGCTATTAACGAAGTATCGATATTTCGTAAAACTAATCAAGCTGCTAAATTTAGAATAGACGTAAACG
GAATAGAGAGAATGAGCGAATTAGTAGCAGACGGAGCTTTAATTGCAACGCCTGCCGGAAGTAGTGCTTACAATTTATCT
GCCGGCGGTCCTATTTTACCGCTTGAATCAAATATGCTATGCCTAACCCCTATCTGCTCTTTTAGACCACGTAGATGGCA
CGGTGCTTTACTGCTTGCATCTGCTACAATTCAATTTAAAATACTTAATACAAATAAACGACCGGTAAATGCTACTGCCG
ATTTTCAGGAGTTTAATAATATCACAAATGTTACCGTTAAATCTACTACGGATACGCCTATCAAACTGCTCTTTAATAAA
AACCATACGCTAGAAGATAGAATTATTAAAGAGCAATTCGGTGGATAA

Upstream 100 bases:

>100_bases
TTGAATGATGACATAATTTAACTTAATATTTATTTTATTACTTTATTCTTATAACTTATTATGAGTTAAGCGTCTATATA
TTAAAAAAGAAATTCGTATA

Downstream 100 bases:

>100_bases
TTATTAAAAAATATTAATAATTTTTGACTAAGAATCAAATTAATATACAATGCCTTGTTAACAATAACTAGGCATTCTAT
ATGAAATCACACAAGTCTTC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNINKIALIYNQNSKHLAIIEEIKKLYNYCKIEEAEAIIVIGGDGALLHNIHRYMHLNIPFYGVNLGNLGFLMNPLDTKN
LSQNIHESTVSILNPLLMQAEDISGQIYTALAINEVSIFRKTNQAAKFRIDVNGIERMSELVADGALIATPAGSSAYNLS
AGGPILPLESNMLCLTPICSFRPRRWHGALLLASATIQFKILNTNKRPVNATADFQEFNNITNVTVKSTTDTPIKLLFNK
NHTLEDRIIKEQFGG

Sequences:

>Translated_255_residues
MNINKIALIYNQNSKHLAIIEEIKKLYNYCKIEEAEAIIVIGGDGALLHNIHRYMHLNIPFYGVNLGNLGFLMNPLDTKN
LSQNIHESTVSILNPLLMQAEDISGQIYTALAINEVSIFRKTNQAAKFRIDVNGIERMSELVADGALIATPAGSSAYNLS
AGGPILPLESNMLCLTPICSFRPRRWHGALLLASATIQFKILNTNKRPVNATADFQEFNNITNVTVKSTTDTPIKLLFNK
NHTLEDRIIKEQFGG
>Mature_255_residues
MNINKIALIYNQNSKHLAIIEEIKKLYNYCKIEEAEAIIVIGGDGALLHNIHRYMHLNIPFYGVNLGNLGFLMNPLDTKN
LSQNIHESTVSILNPLLMQAEDISGQIYTALAINEVSIFRKTNQAAKFRIDVNGIERMSELVADGALIATPAGSSAYNLS
AGGPILPLESNMLCLTPICSFRPRRWHGALLLASATIQFKILNTNKRPVNATADFQEFNNITNVTVKSTTDTPIKLLFNK
NHTLEDRIIKEQFGG

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=152, Percent_Identity=35.5263157894737, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325068, Length=194, Percent_Identity=31.4432989690722, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 28306; Mature: 28306

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINKIALIYNQNSKHLAIIEEIKKLYNYCKIEEAEAIIVIGGDGALLHNIHRYMHLNIP
CCCEEEEEEEECCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHEEEECCC
FYGVNLGNLGFLMNPLDTKNLSQNIHESTVSILNPLLMQAEDISGQIYTALAINEVSIFR
EEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHEEEEE
KTNQAAKFRIDVNGIERMSELVADGALIATPAGSSAYNLSAGGPILPLESNMLCLTPICS
ECCCCEEEEEECHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCEEECCCCCEEEECHHC
FRPRRWHGALLLASATIQFKILNTNKRPVNATADFQEFNNITNVTVKSTTDTPIKLLFNK
CCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCEEEEECC
NHTLEDRIIKEQFGG
CCCHHHHHHHHHCCC
>Mature Secondary Structure
MNINKIALIYNQNSKHLAIIEEIKKLYNYCKIEEAEAIIVIGGDGALLHNIHRYMHLNIP
CCCEEEEEEEECCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHEEEECCC
FYGVNLGNLGFLMNPLDTKNLSQNIHESTVSILNPLLMQAEDISGQIYTALAINEVSIFR
EEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEHEEEEE
KTNQAAKFRIDVNGIERMSELVADGALIATPAGSSAYNLSAGGPILPLESNMLCLTPICS
ECCCCEEEEEECHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCEEECCCCCEEEECHHC
FRPRRWHGALLLASATIQFKILNTNKRPVNATADFQEFNNITNVTVKSTTDTPIKLLFNK
CCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCEEEEECC
NHTLEDRIIKEQFGG
CCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA