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The map label for this gene is ilvE [H]

Identifier: 157825713

GI number: 157825713

Start: 582134

End: 583006

Strand: Direct

Name: ilvE [H]

Synonym: A1C_03195

Alternate gene names: 157825713

Gene position: 582134-583006 (Clockwise)

Preceding gene: 157825706

Following gene: 157825714

Centisome position: 47.29

GC content: 33.79

Gene sequence:

>873_bases
ATGACAATGATAAAACTAGAGCAAATTTTTGGGCATGTTTGGATTAATGGTGATTTAGTTCCTTATCAATTCGCAAGGAT
TCATGTTTTAACTCATAGCCTGCATTATTCAGGATCGGTATTTGAGGGTGAGAGAGCTTATAACGGCAAAGTTTTTAAAC
TAAAAGAACATACGGCAAGGTTAATAAAATCAGCAGAAGCATTAGGTTTAAAAGTACCTTATAGTGTGGACGAGATAATA
AAAGCTCATGAACTTGTAATAAAACAAAATAATATTAAGGATGCATATATAAGACCGCTTATTTGGTGCGGAGACGAATC
ACTAAATATTACTAACCCTGATTTGTCTACTAATCTTTTGATTGCCGGTATTCCATCAATTCCCAGGTCTTTTGAAAAAG
GTATAAATTTACATGTAAGCCGTTGGCGTAAAGCAATGCCTGATAGCACCCCGGTACAATCTAAATCTGCCGCTCAATAT
AATATGGCAATAACGAGTCAAAAAGCAGCTAAAGCTCTTGGCTATGATGATGCATTATTACTTGATTATGAAGGGTATAT
TGCTGAATGTACTACAACAAATATTTTCTTTGTTCAAGATAAAACGTTATATACTCCAATTGCTGATAGATTTTTAAACG
GTATAACAAGACAGACTATTATTGAAATTGCAAAAGATTTAGGTCTAGAAGTAAAAGAAGAGCGCTTGAAATTAGAGCAA
CTAGAAAATTTTACCGGATGTTTTGTTACAGGTACGGCAATTGAGGTGCAAAATATTAGTTCTATAGATCTTGGCAATAA
AAAGCTTATTTTTGAGGATCATAAAATTACAGAACTTTTGAAAGAAGAGTATGGGCGTGTTGTTAGGGAGTAG

Upstream 100 bases:

>100_bases
CAGTAAAATTATTAATATCATAAGCTGTTTTTTTGGACCCCGTGGTCAAGCCACGGGGTGAGATCTTAGATTATATCTAC
TTTAATATAAATATGTGTTA

Downstream 100 bases:

>100_bases
GAATAAGTGCTAAATATTTAATCCAGTGATTAAGTCGTGGGATAACAAATTAGGAAGCTGAACCATGAGGCAAATGCTTC
CTCACAATGACAAATTAATA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTMIKLEQIFGHVWINGDLVPYQFARIHVLTHSLHYSGSVFEGERAYNGKVFKLKEHTARLIKSAEALGLKVPYSVDEII
KAHELVIKQNNIKDAYIRPLIWCGDESLNITNPDLSTNLLIAGIPSIPRSFEKGINLHVSRWRKAMPDSTPVQSKSAAQY
NMAITSQKAAKALGYDDALLLDYEGYIAECTTTNIFFVQDKTLYTPIADRFLNGITRQTIIEIAKDLGLEVKEERLKLEQ
LENFTGCFVTGTAIEVQNISSIDLGNKKLIFEDHKITELLKEEYGRVVRE

Sequences:

>Translated_290_residues
MTMIKLEQIFGHVWINGDLVPYQFARIHVLTHSLHYSGSVFEGERAYNGKVFKLKEHTARLIKSAEALGLKVPYSVDEII
KAHELVIKQNNIKDAYIRPLIWCGDESLNITNPDLSTNLLIAGIPSIPRSFEKGINLHVSRWRKAMPDSTPVQSKSAAQY
NMAITSQKAAKALGYDDALLLDYEGYIAECTTTNIFFVQDKTLYTPIADRFLNGITRQTIIEIAKDLGLEVKEERLKLEQ
LENFTGCFVTGTAIEVQNISSIDLGNKKLIFEDHKITELLKEEYGRVVRE
>Mature_289_residues
TMIKLEQIFGHVWINGDLVPYQFARIHVLTHSLHYSGSVFEGERAYNGKVFKLKEHTARLIKSAEALGLKVPYSVDEIIK
AHELVIKQNNIKDAYIRPLIWCGDESLNITNPDLSTNLLIAGIPSIPRSFEKGINLHVSRWRKAMPDSTPVQSKSAAQYN
MAITSQKAAKALGYDDALLLDYEGYIAECTTTNIFFVQDKTLYTPIADRFLNGITRQTIIEIAKDLGLEVKEERLKLEQL
ENFTGCFVTGTAIEVQNISSIDLGNKKLIFEDHKITELLKEEYGRVVRE

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=262, Percent_Identity=38.5496183206107, Blast_Score=191, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17565728, Length=312, Percent_Identity=27.8846153846154, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32817; Mature: 32686

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMIKLEQIFGHVWINGDLVPYQFARIHVLTHSLHYSGSVFEGERAYNGKVFKLKEHTAR
CCEEEEEHHHCEEEECCCCCCHHHHEEEEEEEEHCCCCCEECCCCCCCCEEEEEHHHHHH
LIKSAEALGLKVPYSVDEIIKAHELVIKQNNIKDAYIRPLIWCGDESLNITNPDLSTNLL
HHHHHHHHCEECCCCHHHHHHHHHHEEECCCCCCHHHCEEEEECCCCCCCCCCCCCCCEE
IAGIPSIPRSFEKGINLHVSRWRKAMPDSTPVQSKSAAQYNMAITSQKAAKALGYDDALL
EEECCCCCHHHHHCCCEEHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHCCCCCEEE
LDYEGYIAECTTTNIFFVQDKTLYTPIADRFLNGITRQTIIEIAKDLGLEVKEERLKLEQ
EECCCEEEEEEECEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHH
LENFTGCFVTGTAIEVQNISSIDLGNKKLIFEDHKITELLKEEYGRVVRE
HCCCCCEEEECCEEEEECCCEECCCCEEEEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMIKLEQIFGHVWINGDLVPYQFARIHVLTHSLHYSGSVFEGERAYNGKVFKLKEHTAR
CEEEEEHHHCEEEECCCCCCHHHHEEEEEEEEHCCCCCEECCCCCCCCEEEEEHHHHHH
LIKSAEALGLKVPYSVDEIIKAHELVIKQNNIKDAYIRPLIWCGDESLNITNPDLSTNLL
HHHHHHHHCEECCCCHHHHHHHHHHEEECCCCCCHHHCEEEEECCCCCCCCCCCCCCCEE
IAGIPSIPRSFEKGINLHVSRWRKAMPDSTPVQSKSAAQYNMAITSQKAAKALGYDDALL
EEECCCCCHHHHHCCCEEHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHCCCCCEEE
LDYEGYIAECTTTNIFFVQDKTLYTPIADRFLNGITRQTIIEIAKDLGLEVKEERLKLEQ
EECCCEEEEEEECEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHH
LENFTGCFVTGTAIEVQNISSIDLGNKKLIFEDHKITELLKEEYGRVVRE
HCCCCCEEEECCEEEEECCCEECCCCEEEEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]