Click here to switch to the map view.

The map label for this gene is murG

Identifier: 157825690

GI number: 157825690

Start: 556779

End: 557927

Strand: Direct

Name: murG

Synonym: A1C_03060

Alternate gene names: 157825690

Gene position: 556779-557927 (Clockwise)

Preceding gene: 157825689

Following gene: 157825691

Centisome position: 45.23

GC content: 33.16

Gene sequence:

>1149_bases
ATGAAAAAAATAATTTTAGCAGCAGGTGGTACGGGCGGGCATTTTTTCCCGGCTGTTGCTCTTGGAGAAGAATTAGTGAA
ACGTGGATATGAAGTTCATTTTATTACTGATTTAAGATGCCAAAAATATATAAATCAGAATCTGGGGTTAATTTTTCATA
TCTTAGATTTAAAACGCTCAAGTAATATTTTTTTATTTTTACCAAACTTATCAATTGCGATCTTAAAAGCTATTAAATTA
TTATACAATATCAGGTCTTCAGCTATTATAGGATTTGGCAGTTATCCTGTTATATCTTCGATGTTTGCGGCAGTTTTTTT
AAGAGTACCGATTATAATTCATGAACAAAATTCTTACCTCGGGAAAGTTAATAAATTTTTTGCAAGCTTTGCTAAAAGGA
TAGCTATTTCTTATGAAGAGGTAAAAAATTTACCGGAATTTGCAAAAAGTAAAATAGTAGTTACCGGTGGGATAGTTAGG
GAGAATATTAGGGAGTTGGATTCTATAGTGTACTCAGCGTCACACCGTGGCTTGATCACGGGGTCCAAAAAAATAAAAAA
AAGACTGGATTCCGTGGTAACGCCACAGAATGACAAGCTTTTTACTATATTCATCTTTGGCGGTAGTCAAGGAGCTACGT
TATTTTCAGAGCTGATACCTGCAAGTATCCAAATTTTGATGCAAAAACAACCAAATCTTAAATTAAATATAATCCAGCAA
GCCGCATTAGATGATCAAGTAAAAATAAAAGATATATACTCGAAATTAAACATTAATTATGAATGTGCCGAATTTTTTGA
TAATATGGCATTGCAATATAAAGAAGCCGATGTAGTGATTTCAAGAGCAGGAGCATCTACTATAGAAGAATTGACATATA
TAGGGTTGCCGGCAATCTTTATTCCACTGCCTAGTGCTGCGGATAATCATCAATATTACAATGCAAAATTATTGGAAGAT
AAAAAAGCAGGATGGTGTTTAGAGCAGAGTGATATTTCTGCAGGAAAATTAGCAGATAAAATACTCGATTTGATAAGTAA
TCCTAAGATATTAGAAGAGGCTTCAAAAAATTTATTAAAAAGAAGAAAAGAAGGGCATGTGTTGTTAAGTGATTTAATAG
AAGGAGTGATTTATCACCCCGTGGCTTGA

Upstream 100 bases:

>100_bases
GTTCTTCAACGCTTGCAATAGCTATCGCTACCGGTATGCTTCTTGGCTTTACAAGACACCGTACTCCTTTAAATTCGTAC
AAAATTCGTAATGTTGAAAT

Downstream 100 bases:

>100_bases
CACCTGGGTCCAGAAACAAATAAAAAATGCTGGATCCTGTGGTTAAGCAACGGGATAACAGTAAGGTACGCAACAATACC
AAAAATACCTCAGAATAACA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKKIILAAGGTGGHFFPAVALGEELVKRGYEVHFITDLRCQKYINQNLGLIFHILDLKRSSNIFLFLPNLSIAILKAIKL
LYNIRSSAIIGFGSYPVISSMFAAVFLRVPIIIHEQNSYLGKVNKFFASFAKRIAISYEEVKNLPEFAKSKIVVTGGIVR
ENIRELDSIVYSASHRGLITGSKKIKKRLDSVVTPQNDKLFTIFIFGGSQGATLFSELIPASIQILMQKQPNLKLNIIQQ
AALDDQVKIKDIYSKLNINYECAEFFDNMALQYKEADVVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAKLLED
KKAGWCLEQSDISAGKLADKILDLISNPKILEEASKNLLKRRKEGHVLLSDLIEGVIYHPVA

Sequences:

>Translated_382_residues
MKKIILAAGGTGGHFFPAVALGEELVKRGYEVHFITDLRCQKYINQNLGLIFHILDLKRSSNIFLFLPNLSIAILKAIKL
LYNIRSSAIIGFGSYPVISSMFAAVFLRVPIIIHEQNSYLGKVNKFFASFAKRIAISYEEVKNLPEFAKSKIVVTGGIVR
ENIRELDSIVYSASHRGLITGSKKIKKRLDSVVTPQNDKLFTIFIFGGSQGATLFSELIPASIQILMQKQPNLKLNIIQQ
AALDDQVKIKDIYSKLNINYECAEFFDNMALQYKEADVVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAKLLED
KKAGWCLEQSDISAGKLADKILDLISNPKILEEASKNLLKRRKEGHVLLSDLIEGVIYHPVA
>Mature_382_residues
MKKIILAAGGTGGHFFPAVALGEELVKRGYEVHFITDLRCQKYINQNLGLIFHILDLKRSSNIFLFLPNLSIAILKAIKL
LYNIRSSAIIGFGSYPVISSMFAAVFLRVPIIIHEQNSYLGKVNKFFASFAKRIAISYEEVKNLPEFAKSKIVVTGGIVR
ENIRELDSIVYSASHRGLITGSKKIKKRLDSVVTPQNDKLFTIFIFGGSQGATLFSELIPASIQILMQKQPNLKLNIIQQ
AALDDQVKIKDIYSKLNINYECAEFFDNMALQYKEADVVISRAGASTIEELTYIGLPAIFIPLPSAADNHQYYNAKLLED
KKAGWCLEQSDISAGKLADKILDLISNPKILEEASKNLLKRRKEGHVLLSDLIEGVIYHPVA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=347, Percent_Identity=27.0893371757925, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RICAH (A8GNC7)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493410.1
- ProteinModelPortal:   A8GNC7
- SMR:   A8GNC7
- STRING:   A8GNC7
- GeneID:   5645283
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_03060
- NMPDR:   fig|293614.3.peg.571
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   RAKA293614:A1C_03060-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- InterPro:   IPR022439
- TIGRFAMs:   TIGR01133
- TIGRFAMs:   TIGR03777

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 42590; Mature: 42590

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIILAAGGTGGHFFPAVALGEELVKRGYEVHFITDLRCQKYINQNLGLIFHILDLKRS
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCC
SNIFLFLPNLSIAILKAIKLLYNIRSSAIIGFGSYPVISSMFAAVFLRVPIIIHEQNSYL
CCEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHH
GKVNKFFASFAKRIAISYEEVKNLPEFAKSKIVVTGGIVRENIRELDSIVYSASHRGLIT
HHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCEEEECHHHHHHHHHHHHHHHHCCCCCEEE
GSKKIKKRLDSVVTPQNDKLFTIFIFGGSQGATLFSELIPASIQILMQKQPNLKLNIIQQ
CCHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
AALDDQVKIKDIYSKLNINYECAEFFDNMALQYKEADVVISRAGASTIEELTYIGLPAIF
HHCCCCHHHHHHHHHHCCCCHHHHHHHHHHEEEECHHEEEECCCCHHHHHHHHHCCCEEE
IPLPSAADNHQYYNAKLLEDKKAGWCLEQSDISAGKLADKILDLISNPKILEEASKNLLK
EECCCCCCCCCEEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RRKEGHVLLSDLIEGVIYHPVA
HHHCCCEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKIILAAGGTGGHFFPAVALGEELVKRGYEVHFITDLRCQKYINQNLGLIFHILDLKRS
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCC
SNIFLFLPNLSIAILKAIKLLYNIRSSAIIGFGSYPVISSMFAAVFLRVPIIIHEQNSYL
CCEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHH
GKVNKFFASFAKRIAISYEEVKNLPEFAKSKIVVTGGIVRENIRELDSIVYSASHRGLIT
HHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCEEEECHHHHHHHHHHHHHHHHCCCCCEEE
GSKKIKKRLDSVVTPQNDKLFTIFIFGGSQGATLFSELIPASIQILMQKQPNLKLNIIQQ
CCHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
AALDDQVKIKDIYSKLNINYECAEFFDNMALQYKEADVVISRAGASTIEELTYIGLPAIF
HHCCCCHHHHHHHHHHCCCCHHHHHHHHHHEEEECHHEEEECCCCHHHHHHHHHCCCEEE
IPLPSAADNHQYYNAKLLEDKKAGWCLEQSDISAGKLADKILDLISNPKILEEASKNLLK
EECCCCCCCCCEEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RRKEGHVLLSDLIEGVIYHPVA
HHHCCCEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA