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The map label for this gene is ruvB [H]

Identifier: 157825660

GI number: 157825660

Start: 524339

End: 525367

Strand: Direct

Name: ruvB [H]

Synonym: A1C_02910

Alternate gene names: 157825660

Gene position: 524339-525367 (Clockwise)

Preceding gene: 157825659

Following gene: 157825661

Centisome position: 42.59

GC content: 37.03

Gene sequence:

>1029_bases
ATGACTAATATATTATCACCTGAAAAAAGTGACAATGATCAAGAATTGCCTATAAGACCGTCATATTTACAGGAATTTGT
CGGTCAACAGCAGATTAAAGAAAATCTTTCGGTATTTATTAAAGCTGCAAAATCTCGGAATCAGCATCTTGATCATACTT
TATTTTACGGTCCACCAGGTCTTGGTAAGACTACGCTTGCCAAAATTATTTCCAACGAAATTGGAGGTAATTTCAAATCC
ACCTCCGGTCCTGCTATACTTAAGGCAGCTGATCTTGCTGCTATTCTTACCAATCTTGAAAAGAACGACGTATTATTTAT
TGATGAAATCCACCGCTTAAATACTGCGGTTGAAGAGATTTTATATCCTGCTATGGAAGATTTTGAGCTTGATATAATTA
TCGGTGAAGGACCTGCCGCAAGGTCAGTGAAAATAACCTTGCCGAAATTTACATTAATCGGGGCTACTACACGCCTTGGG
CTGCTTAGTAATCCTTTGCGTGATAGGTTCGGTATTCCTATGCGGCTTAATTTTTATAATACTGAAGAATTGAAAAAAGT
TCTAAATAGAGCGAGTAAGTTATTTGATATTGATTTGACTGATTCAGGTTCGGAAGAGATAGCAAAAAGAAGTAGAGGAA
CGCCAAGAATTGCATTAAGATTGCTGCGTCGTATAAGAGATTTTGCAGCAGTTGACGGTAAATCAAGAGTAGATAAAGAA
ATCTCTGATTTTGGGTTAAAGCGTTTGGAGGTTGATCTAATAGGACTTGATAGTAATGATTATCGTTATTTGAAATTCAT
AGCGGATCATTATAACGGTGGTCCTGTTGGAATTGAAACGATCGCAGCAGCCCTTTCTGAAGAGCGTGACGCACTTGAAG
AAACCATAGAGCCTTATCTAATACAGATAGGTTTACTACAAAGAACTCCTAGAGGTAGGGTAATCACGATTGCCGCTTTT
GAGCATTTGAAAATGCCGATACCTAATCAATCACATCATCAATTTAATATTTTTAATGAGAATGAATAA

Upstream 100 bases:

>100_bases
TATATAATATAAATCAGTTAAATTATATAGAATCTTAAAATAATTTATAGCATAAAACTATTTTTTAGCTATTATTAGTC
ATCATATTCGATTTAAAATA

Downstream 100 bases:

>100_bases
TAATAATTTAAATGATACTTATACAGCTGCATATGTTATAAAAAGGCTGATAAAAGATCATATTAAACCTTATGCAAATA
AAATATATTTTTCTATATTT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTNILSPEKSDNDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNQHLDHTLFYGPPGLGKTTLAKIISNEIGGNFKS
TSGPAILKAADLAAILTNLEKNDVLFIDEIHRLNTAVEEILYPAMEDFELDIIIGEGPAARSVKITLPKFTLIGATTRLG
LLSNPLRDRFGIPMRLNFYNTEELKKVLNRASKLFDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVDGKSRVDKE
ISDFGLKRLEVDLIGLDSNDYRYLKFIADHYNGGPVGIETIAAALSEERDALEETIEPYLIQIGLLQRTPRGRVITIAAF
EHLKMPIPNQSHHQFNIFNENE

Sequences:

>Translated_342_residues
MTNILSPEKSDNDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNQHLDHTLFYGPPGLGKTTLAKIISNEIGGNFKS
TSGPAILKAADLAAILTNLEKNDVLFIDEIHRLNTAVEEILYPAMEDFELDIIIGEGPAARSVKITLPKFTLIGATTRLG
LLSNPLRDRFGIPMRLNFYNTEELKKVLNRASKLFDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVDGKSRVDKE
ISDFGLKRLEVDLIGLDSNDYRYLKFIADHYNGGPVGIETIAAALSEERDALEETIEPYLIQIGLLQRTPRGRVITIAAF
EHLKMPIPNQSHHQFNIFNENE
>Mature_341_residues
TNILSPEKSDNDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNQHLDHTLFYGPPGLGKTTLAKIISNEIGGNFKST
SGPAILKAADLAAILTNLEKNDVLFIDEIHRLNTAVEEILYPAMEDFELDIIIGEGPAARSVKITLPKFTLIGATTRLGL
LSNPLRDRFGIPMRLNFYNTEELKKVLNRASKLFDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVDGKSRVDKEI
SDFGLKRLEVDLIGLDSNDYRYLKFIADHYNGGPVGIETIAAALSEERDALEETIEPYLIQIGLLQRTPRGRVITIAAFE
HLKMPIPNQSHHQFNIFNENE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=311, Percent_Identity=56.5916398713826, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1787119, Length=249, Percent_Identity=30.5220883534137, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38406; Mature: 38275

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNILSPEKSDNDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNQHLDHTLFYGPPG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
LGKTTLAKIISNEIGGNFKSTSGPAILKAADLAAILTNLEKNDVLFIDEIHRLNTAVEEI
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHH
LYPAMEDFELDIIIGEGPAARSVKITLPKFTLIGATTRLGLLSNPLRDRFGIPMRLNFYN
HHHCCCCCEEEEEECCCCCCCEEEEEECCEEEEECHHHHHHHCCCHHHHCCCCEEEECCC
TEELKKVLNRASKLFDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVDGKSRVDKE
HHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
ISDFGLKRLEVDLIGLDSNDYRYLKFIADHYNGGPVGIETIAAALSEERDALEETIEPYL
HHHCCCEEEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IQIGLLQRTPRGRVITIAAFEHLKMPIPNQSHHQFNIFNENE
EEHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
TNILSPEKSDNDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNQHLDHTLFYGPPG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
LGKTTLAKIISNEIGGNFKSTSGPAILKAADLAAILTNLEKNDVLFIDEIHRLNTAVEEI
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHH
LYPAMEDFELDIIIGEGPAARSVKITLPKFTLIGATTRLGLLSNPLRDRFGIPMRLNFYN
HHHCCCCCEEEEEECCCCCCCEEEEEECCEEEEECHHHHHHHCCCHHHHCCCCEEEECCC
TEELKKVLNRASKLFDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVDGKSRVDKE
HHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
ISDFGLKRLEVDLIGLDSNDYRYLKFIADHYNGGPVGIETIAAALSEERDALEETIEPYL
HHHCCCEEEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IQIGLLQRTPRGRVITIAAFEHLKMPIPNQSHHQFNIFNENE
EEHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA