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The map label for this gene is kdsB [H]

Identifier: 157825649

GI number: 157825649

Start: 517215

End: 517955

Strand: Reverse

Name: kdsB [H]

Synonym: A1C_02855

Alternate gene names: 157825649

Gene position: 517955-517215 (Counterclockwise)

Preceding gene: 157825650

Following gene: 157825647

Centisome position: 42.07

GC content: 35.22

Gene sequence:

>741_bases
ATGCAGCATCAGGACGTTGCTATAATTATCCCCTCAAGGCTAAGTTCAACTAGGCTTAAACAAAAACCGCTGCAGCTTAT
CGGCTCTATAACTTTAATCGAGCGTGTATTCAAACAAATAAATCAAGCTAACCTTGAGCATACATATGTTGCGACCGACT
CGGAAGAGATATCAAATATTATTAAAAAAGTCAGAGGGAAAGTAATATTCACAGATAGTGCTATCCCAACCGGTACTGAC
CGTACTTATGAAGCTTTTAAATTAATTCCAAATAATCAAAACATTAACTACATAGTTAATGTACAGGGAGATATGCCTTT
TATTGAACCTAGCTCTGTTTTGAAAATTATAGAATATTTAAAAAACAGCGAATACGATATTGTTACACCGGTAGTAAAGG
TAGATAGGGAATCAGTGGAAGCTAGTAGTAATGTGACCGTAGCGGTTGACTCGGCGGGGAAAGCATTGTATTTTTCGCGT
AGTCTTATTCCAAACGGTGCAGAAGAATTTTTATATCATGTAGGCATGTATGGTTTTCGCAAAAACGCTTTAGAAAAATT
TGTATCTCTTAAGCCAACTTTTTTAGAAAAAACAGAACGTTTGGAACAATTACGTGTCCTTGAAAACGGCATGACTATAG
GTACATGTTTAGTTGAGAATGTCCCTATTTCCGTAGATACGGAAGAAGACTTAAAAAAAGCAGTAAAATTTTACGAAAAT
ATTAGTAAACTAGGTTTATAA

Upstream 100 bases:

>100_bases
TTCTTAAGTGTACAAATATATTCAAAATTATATTTTACTTTATCGCCGAAAAAGGCTAAGCTGTCAACAATTATTTTTTA
ATTTAATATATAGGAAGTTT

Downstream 100 bases:

>100_bases
TAAATAATGGTACGTTTTATTTTTGTTACCGGCGGCGTTGTTTCAGCACTCGGTAAAGGTATAACGGCTGCATCTCTTGC
TATGCTGTTACAAGCGAAAG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MQHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQINQANLEHTYVATDSEEISNIIKKVRGKVIFTDSAIPTGTD
RTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSVLKIIEYLKNSEYDIVTPVVKVDRESVEASSNVTVAVDSAGKALYFSR
SLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
ISKLGL

Sequences:

>Translated_246_residues
MQHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQINQANLEHTYVATDSEEISNIIKKVRGKVIFTDSAIPTGTD
RTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSVLKIIEYLKNSEYDIVTPVVKVDRESVEASSNVTVAVDSAGKALYFSR
SLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
ISKLGL
>Mature_246_residues
MQHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQINQANLEHTYVATDSEEISNIIKKVRGKVIFTDSAIPTGTD
RTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSVLKIIEYLKNSEYDIVTPVVKVDRESVEASSNVTVAVDSAGKALYFSR
SLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
ISKLGL

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=239, Percent_Identity=33.8912133891213, Blast_Score=130, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27717; Mature: 27717

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQINQANLEHTYVATDSEEISNI
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
IKKVRGKVIFTDSAIPTGTDRTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSVLKIIEYL
HHHHCCCEEEECCCCCCCCCCCEEHEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
KNSEYDIVTPVVKVDRESVEASSNVTVAVDSAGKALYFSRSLIPNGAEEFLYHVGMYGFR
HCCCCEEEHHHHHHCHHHHCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
KNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHH
ISKLGL
HHHHCC
>Mature Secondary Structure
MQHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQINQANLEHTYVATDSEEISNI
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
IKKVRGKVIFTDSAIPTGTDRTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSVLKIIEYL
HHHHCCCEEEECCCCCCCCCCCEEHEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
KNSEYDIVTPVVKVDRESVEASSNVTVAVDSAGKALYFSRSLIPNGAEEFLYHVGMYGFR
HCCCCEEEHHHHHHCHHHHCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
KNALEKFVSLKPTFLEKTERLEQLRVLENGMTIGTCLVENVPISVDTEEDLKKAVKFYEN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHH
ISKLGL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA