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The map label for this gene is lysK

Identifier: 157825634

GI number: 157825634

Start: 498497

End: 500086

Strand: Direct

Name: lysK

Synonym: A1C_02755

Alternate gene names: 157825634

Gene position: 498497-500086 (Clockwise)

Preceding gene: 157825631

Following gene: 157825635

Centisome position: 40.49

GC content: 37.48

Gene sequence:

>1590_bases
ATGTCAGAAATTTGGGAAGATGCTATTAAGTCAAACGCTTGGCCTTTTGTTGAGGCTAAGAAAATATTAGACAGCTTAAA
CGGTAAAACTCCTGAAAAAGGTTACTTATTATTTGAAACGGGGTACGGTCCTTCAGGTTTGCCTCATATAGGTACTTTTG
GTGAAAATGCCCGTATAGTGATGGTGCAGAAAGCGTTTGAGCAATTATCCGATATTCCTACTAAGCTAATTTGCTTTTCT
GATGATATGGACGGACTTCGTAAAGTTCCTAGTAATATCCCACATCCTGAAATGGTAGCTGGGTATATGGATATGCCGCT
TACTTCTATCCCTGATCCGTTCGGTGAGTGTGAAAGTTATGGACATTATATGAACGCAAAGCTTCGCTCATTCCTTGATA
AATTTGGCTTTAAGTATGAATTTTATAGCAGTACTAACTGTTATAAAGCCGGTATGTTTGATGAAATGCTGATAAGAGTG
CTAGAGCAATATGACAAGATAATGGAGCTGATGCTACCGACCTTTAGAGAAGAGCGAAAGGCTACATATTCGCCTTTCAT
GCCTGTATGCCTGAAAACAGGTAAGGTACTGCAAGTACCTATAGAGAAATGGGATGCTAAAGTAGGTACTGTTACATATA
AAGACGAAGCCGGTAATTATATAGAAGTACCGGTAACGGGAGGGCATTGTAAATTACAGTGGAAGCCGGATTTCGGTATG
CGCTGGGCTGCTCTTAAAGTCGATTATGAAATGTACGGCAAAGACCATCTAGCAAATGCTCGACTTTATTCGGAAATTTG
CCGAATCCTAGGAGGCAAGCCGCCAGTGCAGCTATGTTATGAGCTATTTTTAGATGAAAACGGTGAGAAAATATCAAAAT
CAAAAGGTAATAGTATTAGTGTTGATGATTGGCTTAAATATGCTCCCGTTGAAAGTATGGCATTATTTATGTACCAAAAT
CCGACTAGAGCTAAGCGTTTGTTTTTTGATGTAATTCCTAAAAATGTTGATGAATATATTACTTTTAATCAGAAATATCA
TTTAGAAGAGGATAGGGCAAAGCGTTTTGCAAATCCAGTTTATCACATACATCACGGGAATGTACCGAAAATTGAGACTT
TTGGCATTACCTATGTATTGCTTTTAAATCTTACTTCTGTGTGTAATCCTTCCGATAAAACGGTACTTTGGGGATTTATT
AGCAAATATGAGCCAAAAGCAACTCCAAATACTAGCCCTTATCTTGACCACTTAGCAGAATTTGCTATAAGATACTACAA
TGACTTTATTAAAGCACATAAATCATATTTAGCTCCTTCCGAAAAGCATAATGTTATTTTACGGGATATATTAGATATGT
TATCTGATATATCTGATCAAACGGAGGCGGAAGGCATTCAGAAAGCAATATATGATATAGGAATGAGAGCAGGATATGAA
AATCTGCGTGATTACTTTAAAGATTTATATCAGATATTGCTTGGGCAAAGCGAAGGTCCAAGACTCGGAACTTTTATAAA
GCTTTACGGGGTGCAGGAAACGAAGAAGTTGGTCGCAGGTAAGTTGACCATGTTATCTAGAAAAAAATAA

Upstream 100 bases:

>100_bases
TGGGATGACATTAAAAAATTCAAGTGATATTTTACAAATTTACAAATAAATAAATTTAGTATATTGTCACTGATTATTAA
TTAAAGTGCAAGAAAAATAA

Downstream 100 bases:

>100_bases
AAAAGACTGGATCCCGCGATCAAGTCGCGGGATGACACAGAAAATAAAAGCTATTAACAAATGAATGAAATTTTTTGTAG
TACGTTACCTATTTTTTTAA

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSEIWEDAIKSNAWPFVEAKKILDSLNGKTPEKGYLLFETGYGPSGLPHIGTFGENARIVMVQKAFEQLSDIPTKLICFS
DDMDGLRKVPSNIPHPEMVAGYMDMPLTSIPDPFGECESYGHYMNAKLRSFLDKFGFKYEFYSSTNCYKAGMFDEMLIRV
LEQYDKIMELMLPTFREERKATYSPFMPVCLKTGKVLQVPIEKWDAKVGTVTYKDEAGNYIEVPVTGGHCKLQWKPDFGM
RWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISVDDWLKYAPVESMALFMYQN
PTRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRFANPVYHIHHGNVPKIETFGITYVLLLNLTSVCNPSDKTVLWGFI
SKYEPKATPNTSPYLDHLAEFAIRYYNDFIKAHKSYLAPSEKHNVILRDILDMLSDISDQTEAEGIQKAIYDIGMRAGYE
NLRDYFKDLYQILLGQSEGPRLGTFIKLYGVQETKKLVAGKLTMLSRKK

Sequences:

>Translated_529_residues
MSEIWEDAIKSNAWPFVEAKKILDSLNGKTPEKGYLLFETGYGPSGLPHIGTFGENARIVMVQKAFEQLSDIPTKLICFS
DDMDGLRKVPSNIPHPEMVAGYMDMPLTSIPDPFGECESYGHYMNAKLRSFLDKFGFKYEFYSSTNCYKAGMFDEMLIRV
LEQYDKIMELMLPTFREERKATYSPFMPVCLKTGKVLQVPIEKWDAKVGTVTYKDEAGNYIEVPVTGGHCKLQWKPDFGM
RWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISVDDWLKYAPVESMALFMYQN
PTRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRFANPVYHIHHGNVPKIETFGITYVLLLNLTSVCNPSDKTVLWGFI
SKYEPKATPNTSPYLDHLAEFAIRYYNDFIKAHKSYLAPSEKHNVILRDILDMLSDISDQTEAEGIQKAIYDIGMRAGYE
NLRDYFKDLYQILLGQSEGPRLGTFIKLYGVQETKKLVAGKLTMLSRKK
>Mature_528_residues
SEIWEDAIKSNAWPFVEAKKILDSLNGKTPEKGYLLFETGYGPSGLPHIGTFGENARIVMVQKAFEQLSDIPTKLICFSD
DMDGLRKVPSNIPHPEMVAGYMDMPLTSIPDPFGECESYGHYMNAKLRSFLDKFGFKYEFYSSTNCYKAGMFDEMLIRVL
EQYDKIMELMLPTFREERKATYSPFMPVCLKTGKVLQVPIEKWDAKVGTVTYKDEAGNYIEVPVTGGHCKLQWKPDFGMR
WAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISVDDWLKYAPVESMALFMYQNP
TRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRFANPVYHIHHGNVPKIETFGITYVLLLNLTSVCNPSDKTVLWGFIS
KYEPKATPNTSPYLDHLAEFAIRYYNDFIKAHKSYLAPSEKHNVILRDILDMLSDISDQTEAEGIQKAIYDIGMRAGYEN
LRDYFKDLYQILLGQSEGPRLGTFIKLYGVQETKKLVAGKLTMLSRKK

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYK_RICAH (A8GN71)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493354.1
- STRING:   A8GN71
- GeneID:   5645733
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_02755
- NMPDR:   fig|293614.3.peg.512
- eggNOG:   COG1384
- HOGENOM:   HBG294650
- OMA:   SKGNGLT
- ProtClustDB:   PRK00750
- BioCyc:   RAKA293614:A1C_02755-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00177
- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- Gene3D:   G3DSA:1.10.10.350
- TIGRFAMs:   TIGR00467

Pfam domain/function: PF01921 tRNA-synt_1f; SSF48163 tRNA-synt_bind

EC number: =6.1.1.6

Molecular weight: Translated: 60727; Mature: 60595

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 293-293

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIWEDAIKSNAWPFVEAKKILDSLNGKTPEKGYLLFETGYGPSGLPHIGTFGENARIV
CCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEE
MVQKAFEQLSDIPTKLICFSDDMDGLRKVPSNIPHPEMVAGYMDMPLTSIPDPFGECESY
EHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
GHYMNAKLRSFLDKFGFKYEFYSSTNCYKAGMFDEMLIRVLEQYDKIMELMLPTFREERK
HHHHHHHHHHHHHHHCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATYSPFMPVCLKTGKVLQVPIEKWDAKVGTVTYKDEAGNYIEVPVTGGHCKLQWKPDFGM
CCCCCCHHHHHCCCCEEEEEHHHHCCCCCEEEEECCCCCEEEEEEECCEEEEEECCCCCC
RWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSIS
EEEEEEECHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHCCCCCCC
VDDWLKYAPVESMALFMYQNPTRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRFANPV
HHHHHHHCCHHHEEEEEECCCHHHHHHHHHHHCCCHHHHEECCCEECCCHHHHHHHCCCE
YHIHHGNVPKIETFGITYVLLLNLTSVCNPSDKTVLWGFISKYEPKATPNTSPYLDHLAE
EEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCHHHHHHHH
FAIRYYNDFIKAHKSYLAPSEKHNVILRDILDMLSDISDQTEAEGIQKAIYDIGMRAGYE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHH
NLRDYFKDLYQILLGQSEGPRLGTFIKLYGVQETKKLVAGKLTMLSRKK
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEIWEDAIKSNAWPFVEAKKILDSLNGKTPEKGYLLFETGYGPSGLPHIGTFGENARIV
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEE
MVQKAFEQLSDIPTKLICFSDDMDGLRKVPSNIPHPEMVAGYMDMPLTSIPDPFGECESY
EHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
GHYMNAKLRSFLDKFGFKYEFYSSTNCYKAGMFDEMLIRVLEQYDKIMELMLPTFREERK
HHHHHHHHHHHHHHHCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATYSPFMPVCLKTGKVLQVPIEKWDAKVGTVTYKDEAGNYIEVPVTGGHCKLQWKPDFGM
CCCCCCHHHHHCCCCEEEEEHHHHCCCCCEEEEECCCCCEEEEEEECCEEEEEECCCCCC
RWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSIS
EEEEEEECHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHCCCCCCC
VDDWLKYAPVESMALFMYQNPTRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRFANPV
HHHHHHHCCHHHEEEEEECCCHHHHHHHHHHHCCCHHHHEECCCEECCCHHHHHHHCCCE
YHIHHGNVPKIETFGITYVLLLNLTSVCNPSDKTVLWGFISKYEPKATPNTSPYLDHLAE
EEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCHHHHHHHH
FAIRYYNDFIKAHKSYLAPSEKHNVILRDILDMLSDISDQTEAEGIQKAIYDIGMRAGYE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHH
NLRDYFKDLYQILLGQSEGPRLGTFIKLYGVQETKKLVAGKLTMLSRKK
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA