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The map label for this gene is nuoC [H]

Identifier: 157825616

GI number: 157825616

Start: 481414

End: 482037

Strand: Reverse

Name: nuoC [H]

Synonym: A1C_02665

Alternate gene names: 157825616

Gene position: 482037-481414 (Counterclockwise)

Preceding gene: 157825617

Following gene: 157825615

Centisome position: 39.16

GC content: 33.65

Gene sequence:

>624_bases
ATGACGCTAGACAAATTCATTGAAAAACTTGCAGATAAATCTAGCATTTTAATAACTCCGGTCATGGTTAAAGATTACCT
AGCTTATAAAGTCGAGCTTAATTTTTTATTACCATTTTTAAAAGCTTTAAAAGAATCGGCAGAATTACGTTTTACCGTAC
TGACTGATTTATTTGGAGCTGATTTTCCTAAAAGAGATAAAAGATTTGAAGTAGTTTACAACTTATTAAGCTTAAAATTA
AATAAGCGTCTTATAATAAAAGTATATATATCTGAAGAAGAAACTATACCTTCGGCAATGAATATATTTAGTACAGCTTG
TTGGTATGAGCGTGAAGTTTACGATATGTACGGGGTAAATTTCGATGGCAATGACGATAAAAGACGGATACTAACTGATT
ATGAATTTGATGGACATCCATTACGTAAAGATTTCCCGTTAACAGGTTATACACAAGTTAAATATGATGAGCAGCTAAAG
CAAGTAGCTTATGAGCCGGTTAATTGCGATATAGAATATCGTGAGTTTGATTTTAGCTCTCACTGGCATAGCCAGACTTA
CGTATTACCGGGGGATGAGAAGGCAGCCTATGTTATTCCCAAGAAAACGGAAGCTCAAAAATAG

Upstream 100 bases:

>100_bases
GTTGACGTATATGTCCCTGGCTGCCCTCCTACCGCTGAAGCATTAATTTACGGACTTATGCAATTACAGAAAAAAATTAA
ACGCACTACAGGTTTTAAGT

Downstream 100 bases:

>100_bases
CATGACATCAAAACTGTCATTGCGAGGAGGGACATAGTCCCGACGCGGCAACCCAGGAAAAATTATGAAGCAACTGGCTG
TATGTATATTGCTAATAAAC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTLDKFIEKLADKSSILITPVMVKDYLAYKVELNFLLPFLKALKESAELRFTVLTDLFGADFPKRDKRFEVVYNLLSLKL
NKRLIIKVYISEEETIPSAMNIFSTACWYEREVYDMYGVNFDGNDDKRRILTDYEFDGHPLRKDFPLTGYTQVKYDEQLK
QVAYEPVNCDIEYREFDFSSHWHSQTYVLPGDEKAAYVIPKKTEAQK

Sequences:

>Translated_207_residues
MTLDKFIEKLADKSSILITPVMVKDYLAYKVELNFLLPFLKALKESAELRFTVLTDLFGADFPKRDKRFEVVYNLLSLKL
NKRLIIKVYISEEETIPSAMNIFSTACWYEREVYDMYGVNFDGNDDKRRILTDYEFDGHPLRKDFPLTGYTQVKYDEQLK
QVAYEPVNCDIEYREFDFSSHWHSQTYVLPGDEKAAYVIPKKTEAQK
>Mature_206_residues
TLDKFIEKLADKSSILITPVMVKDYLAYKVELNFLLPFLKALKESAELRFTVLTDLFGADFPKRDKRFEVVYNLLSLKLN
KRLIIKVYISEEETIPSAMNIFSTACWYEREVYDMYGVNFDGNDDKRRILTDYEFDGHPLRKDFPLTGYTQVKYDEQLKQ
VAYEPVNCDIEYREFDFSSHWHSQTYVLPGDEKAAYVIPKKTEAQK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=149, Percent_Identity=48.993288590604, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI145693162, Length=143, Percent_Identity=33.5664335664336, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32563621, Length=186, Percent_Identity=43.5483870967742, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71990788, Length=186, Percent_Identity=43.5483870967742, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24656494, Length=210, Percent_Identity=41.4285714285714, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 24394; Mature: 24263

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDKFIEKLADKSSILITPVMVKDYLAYKVELNFLLPFLKALKESAELRFTVLTDLFGA
CCHHHHHHHHCCCCCEEEEHHHHHHHHEEEEHHHHHHHHHHHHHHHHCEEEEEEHHHHCC
DFPKRDKRFEVVYNLLSLKLNKRLIIKVYISEEETIPSAMNIFSTACWYEREVYDMYGVN
CCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
FDGNDDKRRILTDYEFDGHPLRKDFPLTGYTQVKYDEQLKQVAYEPVNCDIEYREFDFSS
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCCCEEEEEECCCC
HWHSQTYVLPGDEKAAYVIPKKTEAQK
CCCCEEEEECCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TLDKFIEKLADKSSILITPVMVKDYLAYKVELNFLLPFLKALKESAELRFTVLTDLFGA
CHHHHHHHHCCCCCEEEEHHHHHHHHEEEEHHHHHHHHHHHHHHHHCEEEEEEHHHHCC
DFPKRDKRFEVVYNLLSLKLNKRLIIKVYISEEETIPSAMNIFSTACWYEREVYDMYGVN
CCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
FDGNDDKRRILTDYEFDGHPLRKDFPLTGYTQVKYDEQLKQVAYEPVNCDIEYREFDFSS
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCCCEEEEEECCCC
HWHSQTYVLPGDEKAAYVIPKKTEAQK
CCCCEEEEECCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA