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The map label for this gene is cysQ [H]

Identifier: 157825534

GI number: 157825534

Start: 403977

End: 404756

Strand: Direct

Name: cysQ [H]

Synonym: A1C_02205

Alternate gene names: 157825534

Gene position: 403977-404756 (Clockwise)

Preceding gene: 157825533

Following gene: 157825536

Centisome position: 32.82

GC content: 33.97

Gene sequence:

>780_bases
ATGAATAATAACTTAATAGCCGCTTTAAAAGATTTAATTATTAATACCGGCAAGGTTGCACTAGATATAAAAAAGGCAGG
AATATTGACTGATATTAAATCAGATGGGTCAGTAGTTACTAATGCCGATAAGGAAATTAGTAAAATAATTTATCAAACTT
TACGAAGCTTAACCTCTCAAATAGCGATAGTATGTGAAGAGCAGCCGCTACCTATATTAAGCAGTGATACTTTTTGGTTA
ATCGATCCTATTGATGGGACACGGAGCTATGTAGACGGTAAAAGTACATATACGGTAAATATAGGGCTTATTGAAAACGG
TTTTCCAACCATAGGCTTGATATATCACCCTGAAACGGCAAAGCTATATTATACCGATGTGAACGGTCGGTTAAAAATCG
AACAGAATTCTAAAGAAATATTTGTTAATCATGAACCAAAACATGAAGAGCTTAATGCGGTAATAGGTTTTTATAATTCA
AATAAAGCTACTAAAGAATTTTTAAGTAAGTATTCATTCGGTCAAATAAATGAAATAGGCAGTTCAATTAAATTATGCTT
AATTGCTGAAGGGGCAGCTGATATATATCCACAATTCAGTCAAACTATGGAATGGGACATAGCTGCAGGTCATGCTTTAA
TTAAAGCCGGCGGCGGTAATATTTTAGATACACATGGACAAGAAATTACTTACGGTAAAGAAAATTTCGCTAATCCTAAT
TTTTTCGCTTGCGGTAAATATTGGTTGGAAAAGTATCCAGCCTGTAATACCTTGGCTTGA

Upstream 100 bases:

>100_bases
CTAGATTGCAGAAAAGCTTCGCTCTTTGCAATGCCAATTTTTAGTATCCATAATGGCAATGCATACGCATGAATGACATA
ATTCGCATTTAATAAATAAT

Downstream 100 bases:

>100_bases
CCACGGTATCCATTAGAAACATTTGTAGTAGTTCAATATTACTGGATACCGCGATCAAGTCGCGGTATGACAATACAGAC
TACTGAATCCATGCTTTCGC

Product: cysQ protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNNNLIAALKDLIINTGKVALDIKKAGILTDIKSDGSVVTNADKEISKIIYQTLRSLTSQIAIVCEEQPLPILSSDTFWL
IDPIDGTRSYVDGKSTYTVNIGLIENGFPTIGLIYHPETAKLYYTDVNGRLKIEQNSKEIFVNHEPKHEELNAVIGFYNS
NKATKEFLSKYSFGQINEIGSSIKLCLIAEGAADIYPQFSQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKENFANPN
FFACGKYWLEKYPACNTLA

Sequences:

>Translated_259_residues
MNNNLIAALKDLIINTGKVALDIKKAGILTDIKSDGSVVTNADKEISKIIYQTLRSLTSQIAIVCEEQPLPILSSDTFWL
IDPIDGTRSYVDGKSTYTVNIGLIENGFPTIGLIYHPETAKLYYTDVNGRLKIEQNSKEIFVNHEPKHEELNAVIGFYNS
NKATKEFLSKYSFGQINEIGSSIKLCLIAEGAADIYPQFSQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKENFANPN
FFACGKYWLEKYPACNTLA
>Mature_259_residues
MNNNLIAALKDLIINTGKVALDIKKAGILTDIKSDGSVVTNADKEISKIIYQTLRSLTSQIAIVCEEQPLPILSSDTFWL
IDPIDGTRSYVDGKSTYTVNIGLIENGFPTIGLIYHPETAKLYYTDVNGRLKIEQNSKEIFVNHEPKHEELNAVIGFYNS
NKATKEFLSKYSFGQINEIGSSIKLCLIAEGAADIYPQFSQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKENFANPN
FFACGKYWLEKYPACNTLA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=207, Percent_Identity=31.4009661835749, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790659, Length=237, Percent_Identity=33.7552742616034, Blast_Score=115, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320493, Length=211, Percent_Identity=26.5402843601896, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24664926, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357303, Length=235, Percent_Identity=23.8297872340426, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357329, Length=210, Percent_Identity=25.2380952380952, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28609; Mature: 28609

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNLIAALKDLIINTGKVALDIKKAGILTDIKSDGSVVTNADKEISKIIYQTLRSLTSQ
CCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHH
IAIVCEEQPLPILSSDTFWLIDPIDGTRSYVDGKSTYTVNIGLIENGFPTIGLIYHPETA
EEEEECCCCCCEECCCCEEEEECCCCCCHHCCCCEEEEEEEEEEECCCCEEEEEECCCCC
KLYYTDVNGRLKIEQNSKEIFVNHEPKHEELNAVIGFYNSNKATKEFLSKYSFGQINEIG
EEEEEECCCEEEEECCCCEEEEECCCCHHCCEEEEEEECCCHHHHHHHHHCCCCCHHHCC
SSIKLCLIAEGAADIYPQFSQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKENFANPN
CCEEEEEEECCCHHCCCCHHCCEEEEEECCEEEEEECCCCEEECCCCEEEECHHHCCCCC
FFACGKYWLEKYPACNTLA
EEEHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNNNLIAALKDLIINTGKVALDIKKAGILTDIKSDGSVVTNADKEISKIIYQTLRSLTSQ
CCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHH
IAIVCEEQPLPILSSDTFWLIDPIDGTRSYVDGKSTYTVNIGLIENGFPTIGLIYHPETA
EEEEECCCCCCEECCCCEEEEECCCCCCHHCCCCEEEEEEEEEEECCCCEEEEEECCCCC
KLYYTDVNGRLKIEQNSKEIFVNHEPKHEELNAVIGFYNSNKATKEFLSKYSFGQINEIG
EEEEEECCCEEEEECCCCEEEEECCCCHHCCEEEEEEECCCHHHHHHHHHCCCCCHHHCC
SSIKLCLIAEGAADIYPQFSQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKENFANPN
CCEEEEEEECCCHHCCCCHHCCEEEEEECCEEEEEECCCCEEECCCCEEEECHHHCCCCC
FFACGKYWLEKYPACNTLA
EEEHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]