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The map label for this gene is mrdB [H]

Identifier: 157825498

GI number: 157825498

Start: 373251

End: 374351

Strand: Reverse

Name: mrdB [H]

Synonym: A1C_01995

Alternate gene names: 157825498

Gene position: 374351-373251 (Counterclockwise)

Preceding gene: 157825499

Following gene: 157825496

Centisome position: 30.41

GC content: 33.97

Gene sequence:

>1101_bases
ATGAATAAAAACTATCTAGAACAATTACAAAAATTACCACTCACTTTAATTTTACTAATCATCTTAATTTGCTGTATTAG
TTTCATTGTACTTTATTCTGCAGCGAATAGCCATTTGCAGCCTTGGGCTTACAAACAAATTATAAATTTTTGTATATTCT
TGCCTTTAGCCATTATTATTGCATTACTTGATTTGCGAATAATATTTAGGCTATCGTATATCTTTTATTTTTGCGTACTC
GCTTTACTAGTAGCCGTGGAGCTTTTTGGCTCAACTGCCATGGGCGGAAAAAGATGGATCGATATCGGTATCGTTAAGCT
TCAGCCTTCCGAACCGATAAAAATTGCCGTTGTACTAATGCTTGCAAGGTATTTCCATTCACTAACAATTGATGATCTAA
GAAAATTCCATAAAGTTATCATACCAATTATAGGAGTTTTAATACCGGCTTTTTTAATAATTAGAGAACCTGATTTAGGT
ACGGGAATGATTGTTTTAATTGTTGCGGCCGTTATATTTTTTGCTGCAGGTTTTAGAATAAAATATTTTATAATAATAGC
TCTCGCTGCTCTTATTAGCCTGCCTATTGCTTGGAATATGATGTATGATTATCAAAAAAAACGAGTGATGGTTTTCTTAG
ATCCAGAACATGATCCGCGCGGTGCTAGTTATAATATTATTCAGTCTAAAATCGCTATAGGTTCAGGTGGCCTATTTGGA
CGCGGTTTAAATCATGGCAGTCAAAGTCATTTAAATTTTCTTCCCGAACATCAAACAGACTTTATCTTTGCTACCTTTGC
CGAAGAGTTCGGATTTATAGGAGGAATATTTTTATTAGTATTATATTTTGCACTTATAACTATTTCTTTATTAATTGCCG
CAAATTGCCGAGAGATTTTTAGTAAATTAATGGTAATAGGTATTAATTCGATTTTATTTAGTCACGTATTTATTAATATA
GCTATGGTTATGGGCTTGCTTCCTGTAGTAGGTGTACCCTTACCGTTTATTTCTTACGGCGGCACAATGATCGCATCCAT
ACTAATAGGCTTTGGACTTGTGATGAATGCTCAGGTACACGGACATACCACTTTAAACTAG

Upstream 100 bases:

>100_bases
TTATTGTAATCCCGCGACTTGATCGCGGGATCCAAAAAAACATAAACAAGACTTGATACCGTTGACAAGCCACAGTATGA
CAGAATAAATATAAAAAACA

Downstream 100 bases:

>100_bases
TTCAATTATATTGATAACATAAACTAAACAACTCTCAGCTATAAGCTGAGATGTTATAAATAGAAGTGTAATCGATTAGA
AATAGGTCATCATTAATAGT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNKNYLEQLQKLPLTLILLIILICCISFIVLYSAANSHLQPWAYKQIINFCIFLPLAIIIALLDLRIIFRLSYIFYFCVL
ALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLMLARYFHSLTIDDLRKFHKVIIPIIGVLIPAFLIIREPDLG
TGMIVLIVAAVIFFAAGFRIKYFIIIALAALISLPIAWNMMYDYQKKRVMVFLDPEHDPRGASYNIIQSKIAIGSGGLFG
RGLNHGSQSHLNFLPEHQTDFIFATFAEEFGFIGGIFLLVLYFALITISLLIAANCREIFSKLMVIGINSILFSHVFINI
AMVMGLLPVVGVPLPFISYGGTMIASILIGFGLVMNAQVHGHTTLN

Sequences:

>Translated_366_residues
MNKNYLEQLQKLPLTLILLIILICCISFIVLYSAANSHLQPWAYKQIINFCIFLPLAIIIALLDLRIIFRLSYIFYFCVL
ALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLMLARYFHSLTIDDLRKFHKVIIPIIGVLIPAFLIIREPDLG
TGMIVLIVAAVIFFAAGFRIKYFIIIALAALISLPIAWNMMYDYQKKRVMVFLDPEHDPRGASYNIIQSKIAIGSGGLFG
RGLNHGSQSHLNFLPEHQTDFIFATFAEEFGFIGGIFLLVLYFALITISLLIAANCREIFSKLMVIGINSILFSHVFINI
AMVMGLLPVVGVPLPFISYGGTMIASILIGFGLVMNAQVHGHTTLN
>Mature_366_residues
MNKNYLEQLQKLPLTLILLIILICCISFIVLYSAANSHLQPWAYKQIINFCIFLPLAIIIALLDLRIIFRLSYIFYFCVL
ALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLMLARYFHSLTIDDLRKFHKVIIPIIGVLIPAFLIIREPDLG
TGMIVLIVAAVIFFAAGFRIKYFIIIALAALISLPIAWNMMYDYQKKRVMVFLDPEHDPRGASYNIIQSKIAIGSGGLFG
RGLNHGSQSHLNFLPEHQTDFIFATFAEEFGFIGGIFLLVLYFALITISLLIAANCREIFSKLMVIGINSILFSHVFINI
AMVMGLLPVVGVPLPFISYGGTMIASILIGFGLVMNAQVHGHTTLN

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=362, Percent_Identity=41.7127071823204, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1786277, Length=347, Percent_Identity=32.8530259365994, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40780; Mature: 40780

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNYLEQLQKLPLTLILLIILICCISFIVLYSAANSHLQPWAYKQIINFCIFLPLAIII
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALLDLRIIFRLSYIFYFCVLALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHH
LARYFHSLTIDDLRKFHKVIIPIIGVLIPAFLIIREPDLGTGMIVLIVAAVIFFAAGFRI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHH
KYFIIIALAALISLPIAWNMMYDYQKKRVMVFLDPEHDPRGASYNIIQSKIAIGSGGLFG
HHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
RGLNHGSQSHLNFLPEHQTDFIFATFAEEFGFIGGIFLLVLYFALITISLLIAANCREIF
CCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLMVIGINSILFSHVFINIAMVMGLLPVVGVPLPFISYGGTMIASILIGFGLVMNAQVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCEEC
GHTTLN
CCCCCC
>Mature Secondary Structure
MNKNYLEQLQKLPLTLILLIILICCISFIVLYSAANSHLQPWAYKQIINFCIFLPLAIII
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALLDLRIIFRLSYIFYFCVLALLVAVELFGSTAMGGKRWIDIGIVKLQPSEPIKIAVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHH
LARYFHSLTIDDLRKFHKVIIPIIGVLIPAFLIIREPDLGTGMIVLIVAAVIFFAAGFRI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHH
KYFIIIALAALISLPIAWNMMYDYQKKRVMVFLDPEHDPRGASYNIIQSKIAIGSGGLFG
HHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
RGLNHGSQSHLNFLPEHQTDFIFATFAEEFGFIGGIFLLVLYFALITISLLIAANCREIF
CCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLMVIGINSILFSHVFINIAMVMGLLPVVGVPLPFISYGGTMIASILIGFGLVMNAQVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCEEC
GHTTLN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]