Click here to switch to the map view.

The map label for this gene is rppH [H]

Identifier: 157825447

GI number: 157825447

Start: 326651

End: 327136

Strand: Reverse

Name: rppH [H]

Synonym: A1C_01740

Alternate gene names: 157825447

Gene position: 327136-326651 (Counterclockwise)

Preceding gene: 157825448

Following gene: 157825432

Centisome position: 26.57

GC content: 34.16

Gene sequence:

>486_bases
ATGAGAAATTCTTCCAAAAAACATCTTGATTTACCATATAGACTAGGAGTCGGCATGATGATATTAAATGCCGATAACCA
TATATTCGTCGGTAAAAGAATAGATACAAAATTATCTGCATGGCAAATGCCTCAAGGTGGGATAGTTCCTGGTGAAACTC
CAAGTATTGCAGCAATGCGTGAGATGTTAGAAGAAATAGGAAGTGATAAAGGATATATTATTGCAGAAAGCAAATGCTGG
TATAGTTATGATGTACCAAGCTTGTTAATACCTAAATTGTGGAACGGTAATTTTCGTGGCCAAAAACAACGCTGGTTTTT
AATTAGGTTTACCGGAAATAACGAAGATATTAATATAAATACCTCTAATCCGGAATTTGACCAATGGCGTTGGGCATCAC
TTGACGAACTATTATCTATTATAATTCCTTTCAAACGGAAACTTTATCAAGCCGTTGTAAAAGAATTTAAATCATTAATT
CAGTAA

Upstream 100 bases:

>100_bases
AATCTTTCATTGAACGTGCTGACAAAGCTATGTATGAAGCTAAAACAACGGGTAGAAATAAAGTAGTAAAATTATAATTG
ATTTTTTAAAGTAAAAAATA

Downstream 100 bases:

>100_bases
AAATTTTATATATCCCTCTCATAAATGAAGAGTTGGTAGACGAATTTTAATTTGGAAAAGAGAGAAGCATCTTGAAACTG
ATGAACGCAGCGTACATATT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRNSSKKHLDLPYRLGVGMMILNADNHIFVGKRIDTKLSAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKCW
YSYDVPSLLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFKSLI
Q

Sequences:

>Translated_161_residues
MRNSSKKHLDLPYRLGVGMMILNADNHIFVGKRIDTKLSAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKCW
YSYDVPSLLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFKSLI
Q
>Mature_161_residues
MRNSSKKHLDLPYRLGVGMMILNADNHIFVGKRIDTKLSAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKCW
YSYDVPSLLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFKSLI
Q

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=154, Percent_Identity=37.6623376623377, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 18665; Mature: 18665

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNSSKKHLDLPYRLGVGMMILNADNHIFVGKRIDTKLSAWQMPQGGIVPGETPSIAAMR
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCHHEECCCCCCCCCCCCCHHHHH
EMLEEIGSDKGYIIAESKCWYSYDVPSLLIPKLWNGNFRGQKQRWFLIRFTGNNEDININ
HHHHHHCCCCCEEEECCCCEEEECCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEE
TSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFKSLIQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNSSKKHLDLPYRLGVGMMILNADNHIFVGKRIDTKLSAWQMPQGGIVPGETPSIAAMR
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCHHEECCCCCCCCCCCCCHHHHH
EMLEEIGSDKGYIIAESKCWYSYDVPSLLIPKLWNGNFRGQKQRWFLIRFTGNNEDININ
HHHHHHCCCCCEEEECCCCEEEECCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEE
TSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFKSLIQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA