BacMap

Definition	Rickettsia akari str. Hartford, complete genome.
Accession	NC_009881
Length	1,231,060

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The map label for this gene is dnaJ [H]

Identifier: 157825371

GI number: 157825371

Start: 249502

End: 250617

Strand: Reverse

Name: dnaJ [H]

Synonym: A1C_01325

Alternate gene names: 157825371

Gene position: 250617-249502 (Counterclockwise)

Preceding gene: 157825372

Following gene: 157825370

Centisome position: 20.36

GC content: 36.92

Gene sequence:

>1116_bases
ATGTCACAAGATTATTACAAAATACTAGGCGTTAGTAAGACAGCTAGCCAAGCGGATCTTAAAAAAGCCTATCTCAAATT
AGCCAAGCAATATCATCCTGATACTACTGACGATAAAGATGCTGAAAAGAAATTTAAAGAAATAAATCGTGCTTATGATG
TTCTAAAAGACGAACAAAAAAGAGCAGCTTACGACCGCTTTGGGCATGATACTTTTCAAAATCAACAGTCACGAGGTGGC
GGAGGAAGTCACGCTGGTTTTCATCATGATATTAACGATATTTTCGGCGACTTCTTTAGTGATTTTATGGGGGGTGGTAG
AAGAAAGCCTACATCAAGTAAGGCTAGAGGTTCGGATTTAAAATATGATCTGACAATTAACCTAGAGGAAGCGTTTCACG
GTATAGAAAAAAATATTAGTTTTTCTAGCGAAGTAAAATGCGATACTTGCCATGGTAGCGGTTCTGAAAAAGGTGAAACA
GTCACTACTTGCGATGCTTGCGGCGGTGTTGGAGCGACTAGAATTCAGCAAGGATTCTTTACAATCGAACAAGCTTGTCA
TAAATGCAAAGGTAACGGACAAATTATAAAAAATCCTTGTAAAAAATGTCATGGCATGGGACGTTGCCATAAACAACGAA
ATTTATCGGTAAATATTCCTGCCGGTGTTGAAAACGGTACTAGAATAAGACATACCGGAGAAGGAGAAGCAGGTATTAGA
GGAGGAAATAGTGGTGATTTATATGTTGATATAGCAATAACACCACATGATATTTATAAGGTAGACGGAGCAAATCTACA
TTGTAAACTACCTATTAGTTTTGTGAATGCCGCTCTTGGAGGGGAGATAGAAGTACCGGTAATTGAAGGAAGGAAAGTCA
ACTTAACAATTCCAGCAGGAACACAAAACGGTGATCAATTAAGGTTACGCAGCAAAGGTATGCCTAAAATGAGATCAACT
ATTAGGGGTGATATGATTACACATATTCATATTGAGGTACCTAAAAATTTATCTAAAAGACAATGTGAGTTACTAGAAGA
ATTCAAAAAAGAATCCATAAGTGAAAAAGAAAATGACGGCAGCTTTTTTAATAAAATGAAAAGTCTATGGTCATGA

Upstream 100 bases:

>100_bases
ATTAGCATTTTTTAACTGGATTGCTTAGTCCATTCCTTCGTAATTTCCTTGCAATGACAAGAAGGCTGCTCCGATGACAA
CCAATTTTATAAATTAAATT

Downstream 100 bases:

>100_bases
ATTTTATTTAACTTTCATATAGAAATAAACCTCCGATGTTATAAAATATTATTATGCTTCTTGTAGAACCTATCTTGTAA
AGAGCGATTTGAAGGAAACA

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSQDYYKILGVSKTASQADLKKAYLKLAKQYHPDTTDDKDAEKKFKEINRAYDVLKDEQKRAAYDRFGHDTFQNQQSRGG
GGSHAGFHHDINDIFGDFFSDFMGGGRRKPTSSKARGSDLKYDLTINLEEAFHGIEKNISFSSEVKCDTCHGSGSEKGET
VTTCDACGGVGATRIQQGFFTIEQACHKCKGNGQIIKNPCKKCHGMGRCHKQRNLSVNIPAGVENGTRIRHTGEGEAGIR
GGNSGDLYVDIAITPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGRKVNLTIPAGTQNGDQLRLRSKGMPKMRST
IRGDMITHIHIEVPKNLSKRQCELLEEFKKESISEKENDGSFFNKMKSLWS

Sequences:

>Translated_371_residues
MSQDYYKILGVSKTASQADLKKAYLKLAKQYHPDTTDDKDAEKKFKEINRAYDVLKDEQKRAAYDRFGHDTFQNQQSRGG
GGSHAGFHHDINDIFGDFFSDFMGGGRRKPTSSKARGSDLKYDLTINLEEAFHGIEKNISFSSEVKCDTCHGSGSEKGET
VTTCDACGGVGATRIQQGFFTIEQACHKCKGNGQIIKNPCKKCHGMGRCHKQRNLSVNIPAGVENGTRIRHTGEGEAGIR
GGNSGDLYVDIAITPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGRKVNLTIPAGTQNGDQLRLRSKGMPKMRST
IRGDMITHIHIEVPKNLSKRQCELLEEFKKESISEKENDGSFFNKMKSLWS
>Mature_370_residues
SQDYYKILGVSKTASQADLKKAYLKLAKQYHPDTTDDKDAEKKFKEINRAYDVLKDEQKRAAYDRFGHDTFQNQQSRGGG
GSHAGFHHDINDIFGDFFSDFMGGGRRKPTSSKARGSDLKYDLTINLEEAFHGIEKNISFSSEVKCDTCHGSGSEKGETV
TTCDACGGVGATRIQQGFFTIEQACHKCKGNGQIIKNPCKKCHGMGRCHKQRNLSVNIPAGVENGTRIRHTGEGEAGIRG
GNSGDLYVDIAITPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGRKVNLTIPAGTQNGDQLRLRSKGMPKMRSTI
RGDMITHIHIEVPKNLSKRQCELLEEFKKESISEKENDGSFFNKMKSLWS

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=355, Percent_Identity=34.6478873239437, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI205360840, Length=355, Percent_Identity=34.6478873239437, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4504511, Length=367, Percent_Identity=32.6975476839237, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI5031741, Length=344, Percent_Identity=31.1046511627907, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI194328758, Length=342, Percent_Identity=31.5789473684211, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI194328760, Length=342, Percent_Identity=31.5789473684211, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI7706495, Length=361, Percent_Identity=30.4709141274238, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI194328762, Length=306, Percent_Identity=28.7581699346405, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI5453690, Length=369, Percent_Identity=26.2872628726287, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI6631085, Length=368, Percent_Identity=26.9021739130435, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI9558755, Length=115, Percent_Identity=45.2173913043478, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI201862518, Length=102, Percent_Identity=46.078431372549, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI201862587, Length=102, Percent_Identity=46.078431372549, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI56549115, Length=102, Percent_Identity=46.078431372549, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI194306642, Length=105, Percent_Identity=47.6190476190476, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI194306640, Length=105, Percent_Identity=47.6190476190476, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI23503241, Length=109, Percent_Identity=43.1192660550459, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI56687498, Length=65, Percent_Identity=56.9230769230769, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI39204547, Length=196, Percent_Identity=30.6122448979592, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21553335, Length=105, Percent_Identity=40.9523809523809, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27151736, Length=104, Percent_Identity=42.3076923076923, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI88501736, Length=104, Percent_Identity=42.3076923076923, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI72534740, Length=105, Percent_Identity=42.8571428571429, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI24308127, Length=88, Percent_Identity=42.0454545454545, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI17388799, Length=66, Percent_Identity=50, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=50, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI47777312, Length=125, Percent_Identity=36, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI45504382, Length=64, Percent_Identity=50, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI22749377, Length=105, Percent_Identity=40, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI29126218, Length=64, Percent_Identity=51.5625, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786197, Length=375, Percent_Identity=47.2, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1787235, Length=355, Percent_Identity=30.9859154929577, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17553098, Length=367, Percent_Identity=35.149863760218, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17553096, Length=367, Percent_Identity=35.149863760218, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17563890, Length=365, Percent_Identity=30.958904109589, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI212645553, Length=362, Percent_Identity=30.3867403314917, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17507263, Length=368, Percent_Identity=28.804347826087, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534355, Length=388, Percent_Identity=26.5463917525773, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554900, Length=166, Percent_Identity=34.3373493975904, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532378, Length=98, Percent_Identity=39.7959183673469, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86563276, Length=102, Percent_Identity=44.1176470588235, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538236, Length=113, Percent_Identity=38.9380530973451, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532476, Length=66, Percent_Identity=46.969696969697, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554644, Length=99, Percent_Identity=42.4242424242424, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=354, Percent_Identity=31.9209039548023, Blast_Score=162, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323870, Length=361, Percent_Identity=33.7950138504155, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321094, Length=399, Percent_Identity=31.077694235589, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323119, Length=390, Percent_Identity=27.6923076923077, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324252, Length=410, Percent_Identity=26.5853658536585, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323813, Length=117, Percent_Identity=39.3162393162393, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322194, Length=103, Percent_Identity=40.7766990291262, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320888, Length=107, Percent_Identity=38.3177570093458, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322388, Length=69, Percent_Identity=46.3768115942029, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324321, Length=64, Percent_Identity=50, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324103, Length=63, Percent_Identity=53.968253968254, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI45552813, Length=381, Percent_Identity=31.758530183727, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI45552811, Length=381, Percent_Identity=31.758530183727, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI45549272, Length=381, Percent_Identity=31.758530183727, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24646562, Length=348, Percent_Identity=31.6091954022989, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24646560, Length=348, Percent_Identity=31.6091954022989, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24646558, Length=348, Percent_Identity=31.6091954022989, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24646556, Length=348, Percent_Identity=31.6091954022989, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357547, Length=348, Percent_Identity=31.6091954022989, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20129487, Length=356, Percent_Identity=29.7752808988764, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24584014, Length=356, Percent_Identity=29.7752808988764, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI85726398, Length=365, Percent_Identity=29.041095890411, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI19920464, Length=353, Percent_Identity=28.328611898017, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28574949, Length=353, Percent_Identity=26.3456090651558, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18858081, Length=353, Percent_Identity=26.628895184136, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24658562, Length=362, Percent_Identity=26.5193370165746, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658555, Length=362, Percent_Identity=26.5193370165746, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654066, Length=104, Percent_Identity=47.1153846153846, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654070, Length=104, Percent_Identity=47.1153846153846, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654068, Length=104, Percent_Identity=47.1153846153846, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654072, Length=104, Percent_Identity=47.1153846153846, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24668492, Length=70, Percent_Identity=47.1428571428571, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668523, Length=64, Percent_Identity=54.6875, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737735, Length=64, Percent_Identity=54.6875, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574723, Length=64, Percent_Identity=54.6875, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=51.5625, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17648033, Length=111, Percent_Identity=41.4414414414414, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584630, Length=111, Percent_Identity=41.4414414414414, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358273, Length=113, Percent_Identity=37.1681415929204, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355911, Length=82, Percent_Identity=43.9024390243902, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 41037; Mature: 40906

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2 ; PS00637 DNAJ_CXXCXGXG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDYYKILGVSKTASQADLKKAYLKLAKQYHPDTTDDKDAEKKFKEINRAYDVLKDEQK
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAAYDRFGHDTFQNQQSRGGGGSHAGFHHDINDIFGDFFSDFMGGGRRKPTSSKARGSDL
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
KYDLTINLEEAFHGIEKNISFSSEVKCDTCHGSGSEKGETVTTCDACGGVGATRIQQGFF
EEEEEEEHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCEEEEHHHCCCCCHHHHHHHHH
TIEQACHKCKGNGQIIKNPCKKCHGMGRCHKQRNLSVNIPAGVENGTRIRHTGEGEAGIR
HHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHCCCEEECCCCCCCCCEEEECCCCCCCCC
GGNSGDLYVDIAITPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGRKVNLTIPAG
CCCCCCEEEEEEECCCCEEEECCCCEEEECCHHHHHHHCCCCEEEEEECCEEEEEEECCC
TQNGDQLRLRSKGMPKMRSTIRGDMITHIHIEVPKNLSKRQCELLEEFKKESISEKENDG
CCCCCEEEECCCCCHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCH
SFFNKMKSLWS
HHHHHHHHHCC
>Mature Secondary Structure 
SQDYYKILGVSKTASQADLKKAYLKLAKQYHPDTTDDKDAEKKFKEINRAYDVLKDEQK
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAAYDRFGHDTFQNQQSRGGGGSHAGFHHDINDIFGDFFSDFMGGGRRKPTSSKARGSDL
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
KYDLTINLEEAFHGIEKNISFSSEVKCDTCHGSGSEKGETVTTCDACGGVGATRIQQGFF
EEEEEEEHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCEEEEHHHCCCCCHHHHHHHHH
TIEQACHKCKGNGQIIKNPCKKCHGMGRCHKQRNLSVNIPAGVENGTRIRHTGEGEAGIR
HHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHCCCEEECCCCCCCCCEEEECCCCCCCCC
GGNSGDLYVDIAITPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGRKVNLTIPAG
CCCCCCEEEEEEECCCCEEEECCCCEEEECCHHHHHHHCCCCEEEEEECCEEEEEEECCC
TQNGDQLRLRSKGMPKMRSTIRGDMITHIHIEVPKNLSKRQCELLEEFKKESISEKENDG
CCCCCEEEECCCCCHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCH
SFFNKMKSLWS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]